Bladder Disorders Clinical Trials

A listing of Bladder Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 10 clinical trials
Neoadjuvant Toripalimab in Combination With Gemcitabine and Cisplatin Therapy in Local Advanced Bladder Cancer Subjects

This is a pre-surgical study involving subjects with local advanced bladder cancer, who are candidates for neoadjuvant therapy. It is a single-arm phase II portion.

carcinoma
gemcitabine
bladder tumor
radical cystectomy
measurable disease
  • 0 views
  • 20 Jun, 2021
  • 1 location
Antibiotic Usage Prior to OnabotulinumtoxinA Injection

Intradetrusor injection of onabotulinumtoxinA, which is performed through a cystoscopic procedure, has been demonstrated to be efficacious in the treatment of both neurogenic and non-neurogenic overactive bladder (OAB), and is FDA approved as a treatment for overactive bladder. Intradetrusor of onabotulinumtoxinA is currently standard of care of patients with OAB …

sepsis
antibiotics
antimicrobials
nitrite
antibiotic therapy
  • 0 views
  • 21 Jun, 2021
  • 1 location
Trilaciclib a CDK 4/6 Inhibitor in Patients With Advanced/Metastatic Bladder Cancer Receiving Chemotherapy Then Avelumab

This is a Phase 2, multicenter, randomized, open-label study evaluating the safety and efficacy of trilaciclib administered with platinum-based chemotherapy followed by trilaciclib administered with avelumab maintenance therapy compared with platinum-based chemotherapy followed by avelumab maintenance therapy in patients receiving first-line treatment for advanced/metastatic bladder cancer.

gemcitabine
cancer
avelumab
metastatic bladder cancer
bladder tumor
  • 0 views
  • 20 Jun, 2021
  • 1 location
Safety and Efficacy Study of Tislelizumab in Combination With BCG in HR-NMIBC Patients (TACBIN-01)

This study is a single-arm, open-label, single-center study to assess the safety of tislelizumab with BCG, and to obtain the preliminary efficacy results in subjects who have been diagnosed with high-risk NMIBC without prior BCG treatment.

carcinoma in situ
carcinoma
intravesical chemotherapy
neutrophil count
metastasis
  • 0 views
  • 20 Jun, 2021
  • 1 location
CONFIRM: Magnetic Resonance Guided Radiation Therapy

This research is being done to determine the safety and feasibility of using a type of radiation guided by magnetic resonance imaging (MRI) and chemotherapy to treat patients with gastric and breast cancer. The name of the radiation machine involved in this study is the MRIdian Linear Accelerator.

cancer chemotherapy
cancer
  • 0 views
  • 12 Jun, 2021
  • 2 locations
Gallbladder Cryoablation in High-Risk Patients

Benign gallbladder disease, including acute cholecystitis, chronic cholecystitis, biliary dyskinesia, and biliary colic, is very common, with over 300,000 surgical cholecystectomies performed per year in the US. Unfortunately, complication rates in elderly patients or patients with many comorbidities are high. These patients are often managed with percutaneous tube drainage of …

chronic cholecystitis
acute cholecystitis
cholecystectomy
anesthesia
  • 0 views
  • 17 Jun, 2021
  • 1 location
Continence Care Registry (ConCaRe )

This observational research study aims to build a multinational ePRO registry of adult end users in outpatient and community settings using intermittent catheter(s) to void via the urethra to manage urinary retention and incomplete bladder emptying. Research participants will be asked to self-report on various attributes of their currently prescribed …

  • 0 views
  • 20 Jun, 2021
  • 1 location
Qualitative Assessment of the Impact of the Connected Catheter on Quality of Life and Participation

This study through the use of semi-structured interviews or focus groups will explore the lived experience with a Connected Catheter and usual customary care (UCC) of catheter users with Neurogenic Lower Urinary Tract Dysfunction and their caretakers to generate user-defined themes regarding bladder function and catheter-related barriers and the daily …

  • 0 views
  • 19 Jun, 2021
  • 1 location
Motor Cortical Neuromodulation in Women With Interstitial Cystitis/Bladder Pain Syndrome

Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) is a common, chronic, and debilitating condition in women. Preliminary evidence suggests that IC/BPS pain can be reduced applying non-invasive repetitive transcranial magnetic stimulation (rTMS) to areas of the brain that regulate pelvic floor muscle activity. However, prior studies have examined rTMS in a very …

pain disorders
pelvic pain
bladder pain
  • 0 views
  • 18 Jun, 2021
  • 1 location
Efficacy of Spartalizumab Across Multiple Cancer-types in Patients With PD1-high mRNA Expressing Tumors

This is an open-label, single arm, non-randomized, multicenter phase II study to evaluate the efficacy of spartalizumab in monotherapy in metastatic patients with Programmed Death-1 (PD1)-high-expressing tumors.

cancer
alopecia
measurable disease
  • 0 views
  • 18 Jun, 2021
  • 10 locations