Bladder Disorders Clinical Trials

A listing of Bladder Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 344 clinical trials
Multiparametric Magnetic Resonance Imaging (MRI) to Improve Bladder Cancer Staging and Treatment Decision-making (SBCT)

The therapeutic approach to bladder cancer is strongly dependent on tumor stage and grade. Patients with non-muscle-invasive tumors (NMIBC) are usually treated with surgical resection of the tumor alone, whereas patients with muscle-invasive tumors (MIBC) ideally undergo neoadjuvant chemotherapy (NCT) and subsequent cystectomy. Magnetic Resonance Imaging (MRI) is emerging as …

bladder tumor
cystoscopy
  • 0 views
  • 27 May, 2022
  • 1 location
QUILT-3.032: A Multicenter Clinical Trial of Intravesical Bacillus Calmette-Guerin (BCG) in Combination With ALT-803 (N-803) in Patients With BCG Unresponsive High Grade Non-Muscle Invasive Bladder Cancer

This is a Phase II/III, open-label, single-arm, multicenter study of intravesical BCG plus N-803 or N-803 only in patients with BCG unresponsive high grade non-muscle invasive bladder cancer (NMIBC). All patients treated in the study will receive via a urinary catheter in the bladder, BCG plus N-803 or N-803 only …

bcg vaccine
bladder tumor
carcinoma
bladder cancer
cancer
  • 290 views
  • 04 Oct, 2022
  • 15 locations
Adjuvant Nivolumab Following Chemo-Radiation in Localized Muscle-Invasive Bladder Cancer (NEXT)

This is a phase 2, single arm, open label trial to evaluate the rate of failure free survival at 2 years after start of chemoradiation with adjuvant nivolumab in adult subjects who undergo chemoradiation for localized bladder cancer.

transurethral resection
radical cystectomy
bladder tumor
carcinoma
invasive bladder cancer
  • 70 views
  • 04 Oct, 2022
  • 1 location
The Effectiveness and Safety of Neoadjuvant Intravesical Mitomycin-C Instillation

The aim of this study is to evaluate the effectiveness and safety of neoadjuvant intravesical mitomycin-C instillation in non-muscle invasive bladder cancer patients

mitomycin
bladder tumor
cancer
bladder cancer
transurethral resection
  • 12 views
  • 23 Apr, 2022
  • 1 location
Electromotive Mitomycin-C (EMDA-MMC) in Preventing Recurrences in High-risk Non-muscle-invasive Bladder Cancer (FB10)

Disease recurrence and progression is a major issue in high risk non-muscle-invasive bladder cancer (NMIBC). The current study compares two adjuvant instillation therapies in the treatment of high risk NMIBC. After resection of the tumour(s), patients will receive either traditional regimen of Bacillus Calmette-Gurin (BCG) instillations or combination treatment consisting …

bladder carcinoma
bladder tumor
carcinoma
mitomycin
bladder cancer
  • 18 views
  • 04 Feb, 2022
  • 7 locations
(CLONEVO): Cell cycLe inhbitiON to Target the EVolution of UrOthelial Cancer (CLONEVO)

Single-arm, open-label window-of-opportunity trial of neoadjuvant Abemaciclib in 20 patients, with tumor tissue obtained as standard of care at tumor resection (pre-Abemaciclib) and cystectomy (post-Abemaciclib)

carcinoma
white blood cell count
radical cystectomy
cancer
transurethral resection
  • 17 views
  • 04 Oct, 2022
  • 2 locations
Multi-parameter Magnetic Resonance Imaging Guides Precise Treatment of Urothelial Carcinoma

PurposeTo evaluate whether immediate multiparametric MRI evaluate the sensitivity of modified neoadjuvant chemotherapy early in patient with muscle invasive bladder cancerMIBC. RationaleMultiparametric MRI may help detect the early changes of bladder cancer receiving neoadjuvant chemotherapy.

recurrent bladder cancer
radical cystectomy
gemcitabine
transurethral bladder excision
carcinoma
  • 0 views
  • 26 Jan, 2021
  • 1 location
Red Clover Isoflavones in Postmenopausal Women With Urge Urinary Incontinence and Overactive Bladder

The purpose of this study is to investigate the effect of red clover isoflavones in postmenopausal women with and without urge urinary incontinence and overactive bladder

overactive bladder
incontinence
  • 0 views
  • 29 Aug, 2021
  • 1 location
A Sham-Controlled Study to Evaluate the Safety and Efficacy of a Smart, Self-Adjusting, Surgery-Free, Wearable Bladder Neuromodulation System for Overactive Bladder (REDUCEOAB)

This is a prospective, multi-center, sham-controlled study comparing the safety and effectiveness of the self-adjusting, surgery-free, wearable Active System to a Sham System on adult Subjects diagnosed with OAB.

overactive bladder
neuromodulation
micturition chart
bladder diary
  • 0 views
  • 07 Jun, 2022
  • 1 location
A Study of Mitomycin-c/ Capecitabine ChemoRadiotherapy Combined With Nivolumab Monotherapy or Ipilumimab and Nivolumab, as Bladder Sparing Curative Treatment for Muscle Invasive Bladder Cancer: the CRIMI Study

A multicenter Phase 1b/2, two stage, open label study of MMC/Capecitabine ChRT combined with nivolumab monotherapy or nivolumab and ipilimumab combination therapy in adult (>18 years) subjects with non-metastatic muscle invasive bladder cancer that qualify for ChRT with curative intent.

serum pregnancy test
carcinoma of the bladder
ipilimumab
bladder carcinoma
combination therapy
  • 6 views
  • 04 Oct, 2022
  • 3 locations