Bladder Disorders Clinical Trials

A listing of Bladder Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 345 clinical trials
Physical Rehabilitation Among Patients Undergoing Radical Cystectomy Due to Urinary Bladder Cancer (CanMoRe)

The main objective of the CanMoRe study is to evaluate the impact of a standardized and individually adapted exercise intervention in Primary Health Care aiming at improving physical function (primary outcome) and habitual physical activity, health related quality of life, fatigue and psychological well-being in patients undergoing radical cystectomy due …

bladder tumor
radical cystectomy
  • 0 views
  • 19 Apr, 2022
  • 1 location
Intracorporeal vs Extracorporeal Urinary Diversion After Robot Assisted Radical Cystectomy

Intracorporeal urinary diversion (ICD) provides superior postoperative outcomes compared to extracorporeal urinary diversion (ECD). The investigators' hypothesis that ICD may provide clinical benefit is based on principles of less bowel and ureteral handling, superior operating room workflow, less exposure to the external environment, and optimal visualization with ICD while utilizing …

urinary diversion
ileal conduit
radical cystectomy
carcinoma
cancer
  • 56 views
  • 23 Mar, 2022
  • 1 location
Window of Opportunity Study of Pembrolizumab Alone and in Combinations in Bladder Cancer

This is a randomized, open-label, window of opportunity platform study in patients with muscle-invasive bladder cancer (MIBC) deemed ineligible to receive cisplatin-based neoadjuvant chemotherapy, who are scheduled to undergo definitive surgery (radical cystectomy). The primary objective of this study is to assess changes to immunogenomic markers after treatment with pembrolizumab …

bladder cancer
invasive bladder cancer
radical cystectomy
transurethral resection
combinations
  • 12 views
  • 28 Jul, 2022
  • 2 locations
The Effectiveness and Safety of Neoadjuvant Intravesical Mitomycin-C Instillation

The aim of this study is to evaluate the effectiveness and safety of neoadjuvant intravesical mitomycin-C instillation in non-muscle invasive bladder cancer patients

bladder cancer
bladder tumor
transurethral resection
invasive bladder cancer
cancer
  • 12 views
  • 23 Apr, 2022
  • 1 location
Adjuvant Nivolumab Following Chemo-Radiation in Localized Muscle-Invasive Bladder Cancer (NEXT)

This is a phase 2, single arm, open label trial to evaluate the rate of failure free survival at 2 years after start of chemoradiation with adjuvant nivolumab in adult subjects who undergo chemoradiation for localized bladder cancer.

cancer treatment
bladder cancer
invasive bladder cancer
radical cystectomy
transurethral resection
  • 70 views
  • 29 Jan, 2022
  • 1 location
Efficacy of Atezolizumab Concurrent With Radiotherapy in Patients With Muscle-invasive Bladder cáncer

Open, multicentre, phase II trial of atezolizumab with concurrent normofractionated radiotherapy in patients with localized muscle-invasive bladder cancer treated with a selective multimodality bladder conservative approach.

bladder cancer
invasive bladder cancer
radical cystectomy
anticoagulants
atezolizumab
  • 10 views
  • 20 Feb, 2022
  • 10 locations
Pembrolizumab (MK-3475) and Bacillus Calmette-Guérin (BCG) as First-Line Treatment for High-Risk T1 Non-Muscle-Invasive Bladder Cancer (NMIBC) and High-Grade Non-Muscle-Invasive Upper Tract Urothelial Carcinoma (NMI-UTUC)]

The purpose of this study is to find out the effectiveness of pembrolizumab in combination with BCG as a first line therapy for participants with high grade T1 bladder cancer who are at "high risk" for BCG alone to be ineffective and are seeking an alternative treatment option to radical …

lymphadenectomy
bladder cancer
metastasis
invasive bladder cancer
radical cystectomy
  • 19 views
  • 25 Jul, 2022
  • 7 locations
Electromotive Mitomycin-C (EMDA-MMC) in Preventing Recurrences in High-risk Non-muscle-invasive Bladder Cancer (FB10)

Disease recurrence and progression is a major issue in high risk non-muscle-invasive bladder cancer (NMIBC). The current study compares two adjuvant instillation therapies in the treatment of high risk NMIBC. After resection of the tumour(s), patients will receive either traditional regimen of Bacillus Calmette-Gurin (BCG) instillations or combination treatment consisting …

bladder cancer
invasive bladder cancer
carcinoma
mitomycin
bladder tumor
  • 18 views
  • 04 Feb, 2022
  • 7 locations
Trimodality Therapy With/Out Durvalumab to Treat Patients With Muscle-Invasive Bladder Cancer

The purpose of this study is to find out what effects durvalumab has on bladder cancer, combined with treatment after completion of surgery, chemotherapy and radiotherapy.

bladder cancer
metastasis
fluorouracil
invasive bladder cancer
transurethral resection
  • 48 views
  • 28 Jun, 2022
  • 39 locations
Nivolumab Plus Chemoradiotherapy in Patients With Muscle-invasive Bladder Cancer (MIBC) Not Undergoing Cystectomy

The purpose of this study is to investigate the effect synchronous use of nivolumab in addition to chemoradiotherapy in patients withnon-metastatic MIBC who are not candidates for radical cystectomy

bladder cancer
invasive bladder cancer
radical cystectomy
carcinoma
TURB
  • 9 views
  • 13 Apr, 2022
  • 1 location