Bladder Disorders Clinical Trials

A listing of Bladder Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 345 clinical trials
A Modular Phase I/IIa, Open-label, Multicentre Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of Ascending Doses of AZD5305 as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Malignancies (PETRA)

This research is designed to determine if experimental treatment with PARP inhibitor, AZD5305, alone, or in combination with anti-cancer agents is safe, tolerable, and has anti-cancer activity in patients with advanced solid tumors.

carboplatin
antineoplastic
paclitaxel
cancer
chemotherapeutic agent
  • 18 views
  • 21 Sep, 2022
  • 30 locations
Study of SO-C101 and SO-C101 in Combination With Pembro in Adult Patients With Advanced/Metastatic Solid Tumors

A multicenter open-label phase 1/1b study to evaluate the safety and preliminary efficacy of SO-C101 as monotherapy and in combination with pembrolizumab in patients with selected advanced/metastatic solid tumors

alopecia
solid tumors
solid tumour
biologic agents
neuropathy
  • 43 views
  • 30 Apr, 2022
  • 7 locations
Sham Controlled Trial of Rapid Induction Percutaneous Tibial Nerve Stimulation

The aim of this study is to determine the efficacy of an accelerated course for percutaneous tibial nerve stimulation (PTNS) induction to treat overactive bladder symptoms. The standard 12 weekly induction treatments may be a patient burden and a more rapid induction may speed up symptomatic improvement.

percutaneous tibial nerve stimulation
bladder symptoms
antimuscarinic
  • 26 views
  • 04 Mar, 2022
  • 1 location
The Use of cineMRI to Evaluate Botox in Patients With Medication Refractory Overactive Bladder

With the goal of providing improved treatment to patients with overactive bladder symptoms (OAB), the investigators seek to apply the new technology of time-resolved (cine) MRI combined with urodynamics (UDS) to understand the exact effect of intravesical botulinum toxin on bladder physiology. The investigators will specifically aim to assess the …

botox
bladder symptoms
medical therapy
incontinence
botulinum toxin
  • 35 views
  • 05 Mar, 2022
  • 1 location
TENS Used for Pain Management During Office Cystoscopy Botox Injections

The purpose of this study is to determine how Transcutaneous Electric Nerve Stimulation (TENS) units affects pain management during office cystoscopic Botox injections and patient satisfaction with the procedure .

transcutaneous electrical nerve stimulation
botox
TENS
  • 7 views
  • 23 Jul, 2022
  • 1 location
A Randomized Clinical Trial of 100 Units of Intradetrusor Onabotulinum Toxin A for Refractory Overactive Bladder - Is 10 Injections Less Painful Than 20 Injections?

The purpose of this research study is to help determine if 10 injections of Botox ® 100 units is less painful than 20 injections of Botox ® 100 units based on effectiveness in reducing urge incontinence episodes. Study will also be assessed for the pain of procedure and adverse outcomes …

botox
onabotulinumtoxina
micturition chart
incontinence
intermittent catheterization
  • 22 views
  • 18 Sep, 2022
  • 2 locations
Intravesical Lactobacillus for Urinary Symptoms Among People With NLUTD Who Use Indwelling Catheters

The objectives of the proposed research among this population are: 1) to define clinically meaningful change (i.e. differentiating states of health and illness) with respect to urinary symptoms, urine inflammation, cultivable bacteria, and the urine ecosystem; and 2) to determine the optimal intravesical Lactobacillus RhamnosusGG (LGG®) dose to be used …

urinary symptoms
  • 0 views
  • 03 Jul, 2022
  • 1 location
Oxybutynin for Post-surgical Bladder Pain and Urgency

Bladder pain and urgency are common after bladder surgery. The objective is to determine if transdermal administration is superior to oral administration in alleviating pain and urgency.

bladder surgery
oxybutynin
  • 3 views
  • 25 Mar, 2022
  • 1 location
Safety and Efficacy Evaluation of Oxybutynin Topical Gel In Children With Neurogenic Bladder

This study will evaluate the safety and efficacy of Oxybutynin Chloride 10% Topical Gel in children 3 to less than 17 years old, who have overactive bladder due to a neurogenic condition. Children will be treated with 0.75 g of gel/day for two weeks. Patients will then return to the …

neurogenic bladder
oxybutynin
overactive bladder
  • 96 views
  • 14 Jul, 2022
  • 5 locations
Behavioral or Solifenacin Therapy for Urinary Symptoms in Parkinson Disease (BOSS PD)

The impact of urinary symptoms in Parkinson disease (PD) extends beyond worsened well-being. Urinary symptoms common in PD, especially incontinence and nocturia, are major risk factors for falls likely due to the combination of urinary urgency and impaired mobility (and falls are a leading cause of mortality in PD), for …

behavior modification
solifenacin
antimuscarinic
constipation
muscarinics
  • 31 views
  • 26 Mar, 2022
  • 2 locations