Asthma (Pediatric) Clinical Trials

A listing of Asthma (Pediatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 27 clinical trials
The Effect of Dupilumab on Lung Function and Related Changes in Airway Volumes Detectable by Functional Respiratory Imaging in Patients With Moderate-severe Asthma

Primary Objective: To assess the effect of dupilumab on lung function and related changes in airway volumes detectable by functional respiratory imaging Secondary Objective: To evaluate the effect of dupilumab at Week 24 on bronchodynamics, hyperinflation, airway resistance, airway wall thickness, ventilation defects and mucus plugging derived from high-resolution computed …

pulmonary function test
fractional exhaled nitric oxide
leukotriene receptor antagonist
bronchodilator
spirometry
  • 12 views
  • 13 Jun, 2021
  • 54 locations
Study to Assess PT010 in Adult and Adolescent Participants With Inadequately Controlled Asthma (KALOS)

This is a variable length study to evaluate the efficacy and safety of budesonide/glycopyrronium/formoterol inhaler in adults and adolescents with severe asthma inadequately controlled with standard of care.

  • 0 views
  • 16 Jun, 2021
  • 180 locations
Dupilumab Asthma Sleep Study

Primary Objective: To assess the effect of dupilumab on sleep Secondary Objectives: To evaluate the effect of dupilumab on additional patient reported sleep outcomes To evaluate the effect of dupilumab on objective sleep assessment To evaluate the effect of dupilumab on asthma symptoms To evaluate the effect of dupilumab on …

pulmonary function test
fractional exhaled nitric oxide
forced expiratory volume
corticosteroids
bronchodilator
  • 40 views
  • 14 Jun, 2021
  • 40 locations
Study to Assess the Efficacy and Safety of MEDI3506 in Adults With Uncontrolled Moderate-to-severe Asthma

Study D9181C00001 is a Phase II, randomised, double-blind, placebo-controlled, parallel group, proof of concept study to evaluate the efficacy, safety, pharmacokinetics (PK) and immunogenicity of MEDI3506 in adult participants with uncontrolled moderate to severe asthma on standard of care (SOC). Up to approximately 80 sites globally will participate in this …

  • 218 views
  • 04 Jun, 2021
  • 72 locations
A Study to Test if TEV-48574 is Effective in Relieving Asthma

The primary objective of the study is to evaluate the effect of TEV-48574 compared with placebo on loss of asthma control (LoAC) in adult patients with T2-low and non-T2 severe asthma uncontrolled on inhaled corticosteroids plus long-acting beta-agonists (ICS+LABA). The secondary efficacy objective is to evaluate the effect of TEV-48574 …

  • 52 views
  • 16 Jun, 2021
  • 70 locations
Study of Efficacy and Safety of CSJ117 in Patients With Severe Uncontrolled Asthma

The purpose of this study is to determine the efficacy and safety of multiple CSJ117 doses (0.5; 1; 2; 4 and 8 mg) inhaled once daily compared with placebo, when added to standard-of-care (SoC) asthma therapy in adult patients with uncontrolled asthma with respect to change from baseline in FEV1 …

corticosteroids
  • 47 views
  • 16 Jun, 2021
  • 115 locations
Efficacy and Safety Study of Benralizumab in Patients With Uncontrolled Asthma on Medium to High Dose Inhaled Corticosteroid Plus LABA (MIRACLE)

This is a randomised, double-blind, parallel group, placebo-controlled study designed to evaluate the efficacy and safety of a fixed 30 mg dose of benralizumab administered subcutaneously for patients with a history of asthma exacerbations and uncontrolled asthma receiving medium to high-dose inhaled corticosteroid plus long-acting 2-agonist (ICS-LABA) with or without …

theophylline
corticosteroids
benralizumab
leukotriene receptor antagonist
bronchodilator
  • 696 views
  • 04 Jun, 2021
  • 63 locations
Benralizumab Airway Remodeling Study in Severe Eosinophilic Asthmatics

The purpose of the study is to evaluate effect of benralizumab on structural and lung function changes in severe eosinophilic asthmatics. Changes will be assessed over 48 week treatment period in patients with persistent symptoms despite standard therapy of inhaled corticosteroids (ICS) plus long acting B2-agonist (LABA) with or without …

pulmonary function test
benralizumab
corticosteroids
airway remodelling
fluticasone
  • 119 views
  • 18 Jun, 2021
  • 48 locations
A Study to Assess the Reduction of Daily Maintenance ICS/LABA Treatment Towards Anti-Inflammatory Reliever Treatment in Patients With Severe Eosinophilic Asthma Treated With Benralizumab

This is a multicentre, randomised, open-label, parallel-group, active-controlled, phase IV study to assess the reduction of daily Symbicort maintenance to anti-inflammatory reliever treatment only in participants with severe eosinophilic asthma on Fasenra treatment, while maintaining asthma control.

benralizumab
ventolin
maintenance treatment
symbicort
  • 7 views
  • 16 Jun, 2021
  • 23 locations
An Exploratory Study to Characterise Changes in Airway Inflammation Symptoms Lung Function and Reliever Use in Adult Asthma Patients

This is a randomised, active-comparator, open-label, parallel-group, multicentre phase IV exploratory study to characterise changes in airway inflammation, symptoms, lung function, and reliever use in asthma patients using SABA (salbutamol) or anti inflammatory reliever (SYMBICORT) as reliever medication in addition to SYMBICORT as daily asthma controller. Eligible patients diagnosed with …

pulmonary function test
fractional exhaled nitric oxide
symbicort
corticosteroids
albuterol
  • 38 views
  • 16 Jun, 2021
  • 6 locations