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Asthma (Pediatric) Clinical Trials

A listing of Asthma (Pediatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (26) clinical trials

CLCZ696B2319E1 OL Extension Study to Evaluate Long-term Safety of Sacubitril/Valsartan in Pediatric Patients With HF

The purpose of this study is to evaluate long-term safety and tolerability data in eligible CLCZ696B2319 (PANORAMA-HF) patients receiving open-label sacubitril/valsartan.

Phase

The Development of a Screening Assay by LC-MS/MS to Monitor Adherence to Asthma Treatment

Phase I: laboratory based study to develop LC-MS/MS assay of urine / blood to detect presence or lack asthma medication in 50 volunteers with asthma. Phase II: once the test is validated it will be tested in a 100 patients attending the asthma clinics to test its clinical utility. Urine ...

Phase N/A

AdheRence to Inhaled Corticosteroids in Asthma

The investigators will evaluate ARICA in Duke primary care clinics to study its feasibility and acceptability using a quasi-experimental pre-post study design. The study will enroll between 32 and 48 adult African Americans with persistent asthma and suboptimal ICS adherence, and their health care providers, to study the use of ...

Phase N/A

Corticosteroids/ 2-agonists in Hair in Asthmatic Patients (CorticHair)

Asthma affects 3-10% of the European population and is a heterogeneous disease in its clinical manifestations and also in its response to treatment. Since therapy is often started at young age and given over many years, with adjustments made on disease control, long-term adherence and efficacy are particular concerns. Adherence ...

Phase N/A

Airway Remodeling During Mepolizumab Treatment

Scientific Rationale & Hypothesis: Chronic airway changes, such as smooth muscle hypertrophy/hyperplasia, reticular basement membrane thickening, goblet cells hyperplasia characterize severe asthma. Chronic inflammation, and especially eosinophilia and T2 cytokines are involved in these structural changes. Increased ASM layer has been associated with eosinophilia for example, but not RBM thickening, ...

Phase N/A

Study of Efficacy of Fevipiprant in Patients With Nasal Polyposis and Asthma

A Phase 3b Proof-of-Concept study to evaluate the ability of fevipiprant dose 1 and dose 2, compared with placebo, as add-on to nasal spray standard-of-care (SoC), in reducing endoscopic nasal polyp score in adult ( 18 years) patients with nasal polyposis and concomitant asthma.

Phase

Assessment of the Safety and Efficacy of Dupilumab in Children With Asthma (Liberty Asthma Excursion)

Study duration per participant is approximatively 64 weeks including a 52 weeks treatment period and 12 weeks post treatment follow-up.

Phase

Trial of Roflumilast in Asthma Management (TRIM)

TRIM is a 24 week, randomized, double-masked, placebo controlled trial that will enroll 38 participants. This study will be take place in five centers of the American Lung Association- Airways Clinical Research Centers (ALA-ACRC). The centers include: Northwestern University Feinberg School of Medicine, Mount Sinai Icahn School of Medicine, Duke ...

Phase

6-Minute Pegboard and Ring Test Unsupported Arm Function Exercise Test in Asthma Patients

Objective: The aim of the study was to evaluate the validity and reliability of the six-minute pegboard and ring test in patients with controlled and partially controlled asthma. Demographic information: Name, age, diagnosis, occupation, body weight, height, The symptoms of the dominant and affected side, CV, family history, obstructive pulmonary ...

Phase N/A

Environmental Polymorphisms Registry

We are establishing a registry-based cohort and repository of biological (e.g. blood, urine,saliva, etc.) and environmental (e.g. household dust) specimens (approximately 20,000 participants) in which the donated specimens are linked to the donor s identities, contact information, and some basic demographics through a personal identification number (PIN). Specimens are available ...

Phase N/A