Seizure Disorders (Pediatric) Clinical Trials

A listing of Seizure Disorders (Pediatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 17 clinical trials
Medtronic Deep Brain Stimulation (DBS) Therapy for Epilepsy Post-Approval Study (EPAS)

The purpose of this post-approval study is to further evaluate the long-term safety and effectiveness of Medtronic DBS therapy for epilepsy on seizure reduction in newly implanted participants through 3 years of follow-up in different geographic populations.

seizure
tonic
video eeg
electroencephalogram
antiepileptics
  • 0 views
  • 01 Aug, 2021
  • 17 locations
A Study to Test the Safety and Tolerability of Brivaracetam in Pediatric Study Participants With Seizures

The purpose of the study is to evaluate the long-term safety and tolerability of brivaracetam.

seizure
electroencephalogram
antiepileptics
brivaracetam
  • 0 views
  • 01 Aug, 2021
  • 22 locations
Study to Assess Intracerebroventricular (ICV) Delivery of CT-010 in Subjects With Focal Seizures With Temporal Lobe Onset With or Without Secondary Generalization

This is a Phase 2 double-blind, randomized, placebo-controlled study to assess the safety and efficacy of ICV delivery of CT-010 via an implantable pump and a cranial port and dual lumen catheter (CIC) in subjects with focal seizures, with temporal lobe onset with or without secondary generalization. Up to 70 …

epilepsy monitoring
anticoagulants
epilepsy
benzodiazepines
central nervous system infection
  • 0 views
  • 26 Jul, 2021
  • 8 locations
Pharmacokinetic Study With an Oral Suspension of Perampanel as Adjunctive Therapy in Pediatric Subjects With Epilepsy

The purpose of this study is to evaluate the pharmacokinetics (PK) of perampanel during the Maintenance Period of the Core Study following oral suspension administration given as an adjunctive therapy in pediatric participants from 1 month to less than 4 years of age with epilepsy.

perampanel
carbamazepine
phenytoin
electroencephalogram
antiepileptics
  • 360 views
  • 31 Jul, 2021
  • 27 locations
Pulvinar Stimulation in Epilepsy: a Pilot Study

Deep brain stimulation (DBS) is one of the neuromodulation techniques that can be indicated in patients suffering from refractory epilepsies, especially when an open resection has failed or is not indicated, and vagal nerve stimulation (VNS) demonstrated no efficacy. Benefits such as reduction of seizure frequency have been shown for …

seizure
epilepsy surgery
  • 0 views
  • 26 Jul, 2021
  • 2 locations
Symptoms of Post-traumatic Stress in Adult Drug-resistant Epilepsies

Epilepsy is a neurological disease that can cause many comorbid psychiatric disorders, among them: generalized anxiety disorder and depression. Many studies suggest a temporal relationship between exposure to a traumatic event and the development of epilepsy. The objective of this research is to study the symptoms of post-traumatic stress disorder …

diabetes
seizure
  • 0 views
  • 31 Jul, 2021
  • 1 location
A Study to Assess the Pharmacokinetics (PK) and Safety of Staccato Alprazolam in Adolescent Study Participants With Epilepsy

The purpose of the study is to assess the pharmacokinetics (PK), tolerability, and safety of Staccato alprazolam in adolescent study participants with epilepsy following single-dose administration.

antiepileptics
generalized epilepsy
  • 0 views
  • 20 Jul, 2021
  • 5 locations
A Study to Evaluate the Efficacy Safety and Pharmacokinetics of Lacosamide in Neonates With Repeated Electroencephalographic Neonatal Seizures

The purpose of the study is to evaluate the efficacy of lacosamide (LCM) versus an Active Comparator chosen based on standard of care (StOC) in severe and nonsevere seizure burden (defined as total minutes of electroencephalographic neonatal seizures (ENS) per hour) in neonates with seizures that are not adequately controlled …

seizure
lacosamide
midazolam
anti-epileptic drug
electroencephalogram
  • 0 views
  • 01 Aug, 2021
  • 18 locations
Surgery as a Treatment for Medically Intractable Epilepsy

Background Medically intractable epilepsy is the term used to describe epilepsy that cannot be controlled by medication. Many people whose seizures do not respond to medication will respond to surgical treatment, relieving seizures completely or almost completely in one-half to two-thirds of patients who qualify for surgery. The tests and …

epilepsy surgery
vagus nerve stimulation
electroencephalogram
partial seizure
complex partial seizures
  • 62 views
  • 01 Aug, 2021
  • 1 location
Epilepsy Prevalence and Intervention Study in Zhejiang Province China

To carry out the epidemiological investigation on epilepsy in Zhejiang Province, China, and then establish early comprehensive intervention to help patients with epilepsy to improve seizure control and the quality of life.

seizure
antiepileptics
  • 0 views
  • 26 Jul, 2021
  • 2 locations