Seizure Disorders (Pediatric) Clinical Trials

A listing of Seizure Disorders (Pediatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 149 clinical trials
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Stereotactic Laser Ablation for Temporal Lobe Epilepsy -SLATE-

The SLATE study is a prospective, single-arm, multicenter study. The study is being conducted to evaluate the safety and efficacy of the Visualase® MRI Guided Laser Ablation System.  

seizure
  • 97 views
  • 11 Jun, 2020
  • 1 location
featured
Stereotactic Laser Ablation for Temporal Lobe Epilepsy (SLATE)

The purpose of this study is to evaluate the safety and efficacy of the Visualase MRI Guided Laser Ablation System for narcotization or coagulation of epileptogenic foci in patients with intractable mesial temporal lobe epilepsy (MTLE)  

temporal lobe epilepsy
seizure
  • 32 views
  • 23 Nov, 2020
  • 1 location
A Study to Evaluate XEN1101 as Adjunctive Therapy in Focal Epilepsy

The XEN1101 Phase 2 clinical trial is a randomized, double-blind, placebo-controlled study that will evaluate the clinical efficacy, safety and tolerability of increasing doses of XEN1101 administered as adjunctive treatment in adult patients diagnosed with focal epilepsy, followed by an optional open-label extension (OLE).

adjunctive treatment
adjunctive therapy
seizure
  • 104 views
  • 25 Jan, 2021
  • 82 locations
Incorporating Multidimensional Psychosocial Interventions Improves the Well-being of Individuals With Epilepsy

The purpose of this study is to incorporate multidimensional self-management programs into the routine care of epilepsy patients. Consenting patients will enroll in one of four interventions that help improve medication adherence, increase seizure awareness and documentation, improve memory and deal with stress and depression.

seizure
  • 72 views
  • 01 Apr, 2021
  • 1 location
Epilepsy Adherence in Children and Technology (eACT)

Fifty-eight percent of children with new-onset epilepsy do not take their antiepileptic drugs (AEDs) as prescribed, which is associated with continued seizures, mortality, poor quality of life, and high healthcare costs. Evidence-based adherence interventions are lacking and critically needed, especially for children with epilepsy, who represent an underserved population in …

antiepileptics
seizure
  • 15 views
  • 24 Jan, 2021
  • 4 locations
A Study to Test the Safety and Tolerability of Brivaracetam in Pediatric Study Participants With Seizures

The purpose of the study is to evaluate the long-term safety and tolerability of brivaracetam.

electroencephalogram
brivaracetam
antiepileptics
seizure
  • 0 views
  • 01 Aug, 2021
  • 21 locations
Prevention of Epilepsy by Reducing Neonatal Encephalopathy

The aim of the study is to examine if a pragmatic, evidenced based and generalisable intrapartum care bundle involving birth companions and empowering mothers will reduce birth injury-related epilepsy at 18 months of age in India. The care bundle will have four key elements (interventions): (1) birth companion providing constant …

electroencephalogram
  • 0 views
  • 25 Jan, 2021
  • 3 locations
Bridging the Childhood Epilepsy Treatment Gap in Africa

About half of the world's children with epilepsy do not receive treatment - known as the epilepsy treatment gap - with significantly higher rates (67%-90%) in low- and middle-income countries (LMICs). We will conduct the first cluster-randomized clinical trial (cRCT) to determine the efficacy, implementation, and cost-effectiveness of a novel …

seizure
  • 0 views
  • 29 Mar, 2021
  • 3 locations
Medtronic Deep Brain Stimulation (DBS) Therapy for Epilepsy Post-Approval Study (EPAS)

The purpose of this post-approval study is to further evaluate the long-term safety and effectiveness of Medtronic DBS therapy for epilepsy on seizure reduction in newly implanted participants through 3 years of follow-up in different geographic populations.

tonic
electroencephalogram
video eeg
antiepileptics
seizure
  • 0 views
  • 01 Aug, 2021
  • 16 locations
A Study to Evaluate the Efficacy and Safety of Brivaracetam in Study Participants (>=16 to 80 Years of Age) With Epilepsy

The purpose of the study is to evaluate the efficacy of brivaracetam (BRV) compared to placebo (PBO) as adjunctive treatment in subjects (>=16 to 80 years of age) with partial seizures with or without secondary generalization despite current treatment with 1 or 2 concomitant antiepileptic drugs (AEDs) and to assess …

brivaracetam
adjunctive treatment
vagus nerve stimulation
antiepileptics
partial seizure
  • 840 views
  • 16 Jul, 2021
  • 111 locations