Seizure Disorders (Pediatric) Clinical Trials

A listing of Seizure Disorders (Pediatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 102 clinical trials
Epilepsy Adherence in Children and Technology (eACT) (eACT)

Fifty-eight percent of children with new-onset epilepsy do not take their antiepileptic drugs (AEDs) as prescribed, which is associated with continued seizures, mortality, poor quality of life, and high healthcare costs. Evidence-based adherence interventions are lacking and critically needed, especially for children with epilepsy, who represent an underserved population in …

antiepileptics
seizure
  • 71 views
  • 23 Apr, 2022
  • 3 locations
Prevention of Epilepsy by Reducing Neonatal Encephalopathy (PREVENT)

The aim of the study is to examine if a pragmatic, evidenced based and generalisable intrapartum care bundle involving birth companions and empowering mothers will reduce birth injury-related epilepsy at 18 months of age in India. The care bundle will have four key elements (interventions): (1) birth companion providing constant …

electroencephalogram
  • 0 views
  • 07 Jun, 2022
  • 2 locations
Incorporating Multidimensional Psychosocial Interventions Improves the Well-being of Individuals With Epilepsy

The purpose of this study is to incorporate multidimensional self-management programs into the routine care of epilepsy patients. Consenting patients will enroll in one of four interventions that help improve medication adherence, increase seizure awareness and documentation, improve memory and deal with stress and depression.

seizure
  • 111 views
  • 09 Jul, 2022
  • 1 location
Tele-epic (Telemedicine for Epilepsy Care) (Tele-epic)

Epilepsy is a chronic condition that requires consistent follow-up aimed at seizure control, surveillance of comorbidities, monitoring of antiepileptic drugs (AED) levels and side effects. Patients may encounter difficulties to be assessed adequately and the disease burden is increased by the need for travelling across the country for medical consultations. …

antiepileptics
epilepsy
antiepileptic
seizure
  • 0 views
  • 21 Mar, 2022
  • 1 location
A Study to Evaluate Efficacy and Safety of Vatiquinone for Treating Mitochondrial Disease in Participants With Refractory Epilepsy (MIT-E)

This is a parallel-arm, double-blind, placebo-controlled study with a screening phase that includes a 28-day run-in phase to establish baseline seizure frequency, followed by a 24-week, randomized, placebo-controlled phase. After completion of the randomized, placebo-controlled phase, participants may enter a 48-week, long-term, extension phase during which they will receive open-label …

antiepileptics
vatiquinone
alpers
leigh's disease
acidosis
  • 233 views
  • 02 Jun, 2022
  • 25 locations
Outcomes Mandate National Integration With Cannabis as Medicine (OMNI-Can)

This will be a multistate, multicenter clinical study to determine the efficacy and safety of medical cannabis for a wide variety of chronic medical conditions.

brimonidine tartrate ophthalmic solution
medical marijuana
covid-19
disease or disorder
Accepts healthy volunteers
  • 15111 views
  • 13 Jun, 2022
  • 16 locations
Localization of the Reward Positivity to ACC

The exact function of the anterior cingulate cortex (ACC) is one of the largest riddles in cognitive neuroscience and a major challenge in mental health research. ACC dysfunction contributes to a broad spectrum of neurological and psychiatric disorders, such as depression, ADHD, Parkinson's disease, OCD and many others, but nobody …

  • 0 views
  • 14 May, 2021
  • 1 location
Study to Assess Intracerebroventricular (ICV) Delivery of CT-010 in Subjects With Focal Seizures With Temporal Lobe Onset With or Without Secondary Generalization

This is a Phase 2 double-blind, randomized, placebo-controlled study to assess the safety and efficacy of ICV delivery of CT-010 via an implantable pump and a cranial port and dual lumen catheter (CIC) in subjects with focal seizures, with temporal lobe onset with or without secondary generalization. Up to 70 …

cancer
valproate
cranial surgery
status epilepticus
functional assessment
  • 0 views
  • 26 Jul, 2021
  • 8 locations
Diffusion Tensor and Functional Connectivity Imaging in Pediatric Epilepsy: Imaging/Histology Correlation (DTI/SEP)

To determine the utility of diffusion tensor magnetic resonance imaging in the preoperative workup of children with intractable epilepsy referred for surgery.

epilepsy
diffusion tensor imaging
intractable epilepsy
  • 13 views
  • 06 Jun, 2022
  • 1 location
Single Neurons Responses During Visual Recognition in Epileptic Patients (REUNIE)

The purpose is to evaluate specific capacities of face detection of individual neurons by comparison with their capacity of object detection in medial temporal lobe and ventral temporal cortex in epileptic patients. Secondary purpose is to evaluate specific capacities of detection of known faces of individual neurons by comparison with …

partial epilepsy
  • 20 views
  • 23 Feb, 2022
  • 1 location