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COPD (Chronic Obstructive Pulmonary Disease) Clinical Trials

A listing of COPD (Chronic Obstructive Pulmonary Disease) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (288) clinical trials

An Educational Intervention to Improve Disease Management Knowledge of Hospitalized Patients With COPD

A prospective cohort study utilizing a pre-test/post-test design will be used to test a COPD education intervention on a convenience sample of 30 patients with a diagnosis of COPD. Study participants will complete the Chronic Obstructive Pulmonary Disease questionnaire (COPD-Q) to assess their COPD knowledge. Next, a respiratory therapist will ...

Phase N/A

High Flow Nasal Cannula and Aerobic Capacity Training

Design: randomized, single blind, controlled trial. The main goal of this study is to compare the exercise tolerance in COPD patients after an 8 week pulmonary rehabilitation program using High Flow Nasal Cannula or The Venturi Mask. The exercise tolerance will be measured in seconds in a Constant Load Treadmill ...

Phase N/A

Effect of Extracorporeal CO2 Removal in Stable Hypercapnic COPD Patients

Chronic hypercapnic respiratory failure is common in stable COPD patients in a terminal phase of their disease In an attempt to correct or slow down the rate of rise of PaCO2, long-term noninvasive mechanical ventilation (NIV) has been proposed. Only very few studies demonstrated the clinical efficacy of NIV. Indeed ...

Phase N/A

Predictive Value of Spirometric PIF to Produce PIF Rate Needed for the Use of Current DPI's.

The correct use of dry powder inhalers (DPI) crucially depends on the peak inspiratory flow (PIF) that the patient can generate when overcoming internal resistance of the inhaler device. It has been shown that some patients cannot achieve sufficient peak inspiratory flows with some DPI's, especially in the elderly population. ...

Phase N/A

Development of a MID for the 1-minute Sit-to-stand Test

In this study we develop the minimal important difference for the 1-minute sit-to-stand-test (STST) with an anchor-based method. First step of this study is to find out the differences in the number of repetitions during 1-minute STST, 6-minute walk distance and health-related quality of life from pre to post inpatient ...

Phase N/A

Association Study Between CYP1A2 Gene Polymorphisms and Metabolism of Theophylline

The aim of this study is to determine whether common CYP1A2 gene polymorphisms effect metabolism of theophylline in Han and Uygur Patients with chronic obstructive pulmonary disease patients.

Phase N/A

Rehabilitation of Patients With Lung Chronic Obstructive Pulmonary Disease

Chronic obstructive pulmonary disease (COPD) is characterized by the obstruction is not fully reversible airway, where the severity of the disease and the prognosis is not determined solely by changes in lung function. Pulmonary rehabilitation is a multidisciplinary program of care for patients with chronic respiratory diseases, individually designed to ...

Phase N/A

Withdrawal of Inhaled Corticosteroids in Primary Care Patients With COPD

Rationale: Because long-term use of ICS is associated with an increased likelihood of side-effects such as increased risk of pneumonia and loss of bone density, it is important to limit prescription of ICS to patients who have a clear indication for this treatment. In addition, avoiding unnecessary treatment with ICS ...

Phase N/A

Effect of Magnesium Supplementation in COPD

Magnesium (Mg) is involved in several pathways that could be affected in chronic obstructive pulmonary diseases (COPDs), namely in the contractility and excitability of neuro-muscolar endothelial cells and low-grade inflammation, a typical state of COPD. In this sense, several randomized controlled trials (RCTs) confirmed a positive role of Mg in ...

Phase N/A

Adjuvant Therapy for Severe COPD Patients in the Stable Phase by an Oxyhydrogen Generator With Nebulizer

In this study, severe COPD patients in stable phase who were included in both treatment and control groups, administered randomly oxyhydrogen generator with nebulizer (treatment group) or oxygen Nebulizer Machine control group for adjuvant therapy. The therapeutic outcomes in both treatment and control groups are analyzed and evaluated to verify ...

Phase N/A