COPD (Chronic Obstructive Pulmonary Disease) Clinical Trials

A listing of COPD (Chronic Obstructive Pulmonary Disease) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 850 clinical trials
Optimizing CO2 Injection Technique for EVAR

Automated carbon dioxide (CO2) angiography is considered a safe diagnostic alternative to standard iodinated contrast medium (ICM) for endovascular aortic repair (EVAR) of abdominal aortic aneurysm (AAA), especially in patients with preoperative renal function impairment. Recent literature experiences describe the use of automated CO2 angiography in EVAR. One of the …

  • 26 Apr, 2022
  • 1 location
Does Smoking Effect Spinal Anesthesia?

Background In the last 10 years, the rate of smoking in women of childbearing age has increased gradually. The smoking affects general anesthesia negatively. Can smoking also affect regional anesthesia in pregnant women? Our aim in this study is to investigate the effects of smoking on spinal anesthesia applied for …

Accepts healthy volunteers
  • 16 May, 2022
  • 1 location
Multivariable Artificial Pancreas: Detecting and Mitigating Unannounced Physical Activity and Acute Psychological Stress

The objective of this proposal is to demonstrate a viable, functionally integrated multivariable artificial pancreas (mvAP) that will address meal, physical activity (PA) and acute psychological stress (APS) challenges without any manual inputs to better regulate glucose levels of people with diabetes. Acute psychological stress and many other forms of …

  • 25 Jul, 2022
  • 1 location
Smoking Cessation and Functional CT Assessment

The investigators will study the effect of pulmonary arterial vasodilation to see if it eliminates indices of persistent lung injury in smokers that are susceptible to emphysema.

sildenafil 20 mg
forced expiratory volume
pulmonary disease
  • 02 Mar, 2022
  • 1 location
Zephyr Valve Registry (ZEVR) (ZEVR)

The purpose of this Post-Approval Registry is to gather ongoing safety and effectiveness assessment of the Zephyr Valve treatment in a real-world setting.

  • 22 Mar, 2022
  • 6 locations
A Trial on the Effects of Bronchoscopic Lung Volume Reduction in Severe Emphysema. (SOLVE)

Rationale: The published clinical trials investigating the bronchoscopic lung volume reduction, showing important patient-related improvements in efficacy, led to the acknowledgement of the treatment in the GOLD-COPD2017 guidelines. Interaction with pulmonary rehabilitation, impact on patient-reported outcomes, physical activity, and extrapulmonary consequences are all topics to gain more insight in. This …

lung volume reduction
rehabilitation program
pulmonary disease
  • 24 Apr, 2022
  • 1 location
STRIVE Post-Market Registry Study

This is a single-arm, prospective, multi-center, Registry study to evaluate the long-term safety and effectiveness of the Spiration Valve System (SVS) for the treatment of severe emphysema in a post-market setting.

  • 06 Oct, 2021
  • 2 locations
Effect of EPAP Device on Emphysema and Lung Bullae

The purpose of this study is to evaluate the safety and the effects and of the application of Expiratory Positive Airway Pressure (EPAP) device on Dynamic Hyperinflation and dyspnea in patients with Emphysema and pulmonary bullae.

  • 19 Apr, 2022
  • 1 location
A Hospital-at-Home Pilot in Singapore

Hospital-at-home models seek to address the impending shortage of hospital beds by reimagining the way we deliver acute hospital-level care - substituting the ward for a patient's home. Such programmes have been well established in other countries such as Australia, Europe and USA to be a less costly way to …

  • 16 Apr, 2021
  • 2 locations
Chronic Cannabis Smoking Oxidative Stress and the Pulmonary Innate Immune Response

This study plans to evaluate the effects of chronic cannabis smoking on lung health by evaluating its effects on pulmonary health, lung physiology and alveolar macrophage function.

  • 28 Jun, 2021
  • 1 location