Restless Leg Syndrome Clinical Trials

The study will compare the safety, effectiveness and tolerability of gabapentin (Neurontin) versus gabapentin enacarbil (Horizant) as treatment restless leg syndrome.

If you're experiencing symptoms of Restless Legs Syndrome (RLS), learn more about this medical research study of an investigational RLS drug. Local doctors are currently conducting the CONCORD medical research study of a Restless Legs Syndrome (RLS) study drug. They want to evaluate an approved dose strength with two investigational ...

Patient Inclusion Criteria: Ages 18+ RLS diagnosis 15 nights or more in past month with RLS symptoms Must stop all RLS medications 2 weeks prior No Horizant usage in past Men or women 18 years of age or older History of RLS symptoms for at least 15 nights/month Documented RLS ...

Patient Inclusion Criteria: Ages 18-60 SPMS diagnosis Must be able to walk Diagnosed with MS as defined by the modified McDonald criteria SPMS defined as relapsing-remitting disease with recent progression in MS-related neurological deficits EDSS score 3.0 - 6.0, inclusively Presence of myelin reactive T-cells Patient Exclusion Criteria: Diagnosed with ...

Do you have Restless Legs Syndrome with iron-deficiency anemia?  

Restless leg syndrome (RLS) is a common neurological disorder whose diagnosis is only clinical. The efficacy of dopaminergic agents in improvement of sensorimotor symptoms advance the hypothesis that altered dopaminergic transmission is at the origin of this condition. RLS usually leads to a sleep fragmentation, which induces sometimes severe insomnia ...

Restless leg syndrome (RLS) is sleep disorder characterized by an unpleasant feeling in the lower limbs, which can be accompanied by paresthesias, and need for urgent movement of the legs. Its diagnosis is clinical, based on an International Committee of the Study of RLS (International Restless Legs Syndrome Study) questionnaire. ...

The primary objective is to assess the pharmacokinetics (PK) of gabapentin following the single-dose administration of HORIZANT (Gabapentin Enacarbil) in adolescents (13 to 17 years of age) diagnosed with moderate-to-severe Primary Restless Legs Syndrome (RLS).

Restless legs syndrome (RLS) is a medical condition in which there is an almost irresistible urge to move the legs in response to uncomfortable, difficult-to-describe leg sensations that are usually worse in the evening and especially noticeable when inactive such as sitting in a chair watching TV or when resting ...

This will be a Phase II, randomized, placebo-controlled study. All subjects who meet the inclusion criteria, with no exclusion criteria, will qualify to enter the Screening Phase. The study will enroll 70 eligible subjects to receive blinded study drug in Treatment Phase I. All eligible subjects will be randomized in ...