Knee Surgery Clinical Trials

A listing of Knee Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 61 clinical trials
Multi-Center Clinical Evaluation of the ATTUNE Revision System in Complex Primary Total Knee Arthroplasty

Five-year, Prospective, multi-center, non-randomized, non-controlled study of the ATTUNE® Revision total knee prostheses, utilizing the fixed bearing (FB) and rotating platform (RP) tibial component with the posterior stabilizing (PS) femoral component in complex primary total knee arthroplasty.

  • 27 Oct, 2022
  • 29 locations
Fixed Versus Adjustable Loop in ACL Reconstruction

Study Aims and Objectives: To investigate the following null hypothesis: that there is no difference in clinical and functional outcome when comparing outcomes of Anterior Cruciate Ligament (ACL) reconstruction when comparing femoral side graft fixation with either a fixed versus an adjustable suspensory loop system. The research team will achieve …

meniscal tear
knee joint laxity
anterior cruciate ligament injury
  • 29 Jan, 2022
  • 1 location
Traditional Versus Alternative Alignment in TKR

As many as 20% of patients are unhappy with the results of total knee replacement (TKR). Various changes to surgical technique have tried to address this but have not led to a significant improvement in the numbers of patients satisfied with their operation. Recently, attention has focussed on alignment of …

Accepts healthy volunteers
  • 30 May, 2022
  • 1 location
RCT Measuring the Effect of the ERVIN Software

The randomised clinical trial investigates the effect of using a clinical decision support system (CDSS) aiming to provide the patients and surgeons with greater transparency concerning the obtainable changes in function and health related quality of life (HRQoL) when patients are to decide if they should undergo hip- or knee …

  • 11 Mar, 2021
  • 1 location
Combined Cryotherapy With Compression Versus Cryotherapy Alone After Orthopaedic Surgery

Cryotherapy has been used to enhance recovery after orthopaedic surgery. Many devices are available but few can guarantee a temperature regulation during a prolonged time and therefore have been criticized. The arrival of new advanced cryotherapy devices made it possible to test the effect of prolonged cooling on rehabilitation after …

  • 26 Apr, 2022
  • 1 location
Implementation of Indication Criteria for Total Knee Replacement in Osteoarthritis (Value-based TKR)

The aim of this trial is to investigate the effect of a medical decision aid (EKIT-Tool) on decision quality for knee arthroplasty.

total knee replacement
joint reconstruction
  • 29 Aug, 2021
Duloxetine RCT on Postop TKA Outcomes

The aim of this study is to determine if duloxetine is associated with differences in post-operative pain, patient-reported outcome measures, and opioid consumption in patients undergoing primary total knee arthroplasty compared to patients who do not receive the medication. If so, duloxetine has the potential to become widely incorporated into …

Accepts healthy volunteers
  • 26 Nov, 2021
  • 1 location
Effect of Ultrasound-guided H-FICB in Patients Undergoing Arthroscopic Knee Surgery

Arthroscopic knee surgery is a minimally invasive operation. Postoperative pain usually occurs, especially within 24 hours after surgery, the incidence of pain can be more than 76%. Pain will

  • 05 May, 2022
  • 1 location
Using Peripheral Nerve Stimulation (PNS) to Treat Chronic Post-surgical Pain (CPSP) After Knee Surgery

SPRINT PNS System will be offered to patients with postoperative knee pain following primary unilateral total knee arthroplasty (TKA) who meet eligibility criteria and consistent with established coverage policy. SPRINT PNS System will be implanted for 60 days. At the discretion of the physician, the first lead may be placed …

total knee replacement
knee surgery
knee pain
chronic pain
  • 24 Mar, 2022
  • 1 location
Ultrasound-guided H-FICB for Arthroscopic Knee Surgery: What is the Optimal Dose of Dexmedetomidine?

choose the better way. A double-blind, randomized controlled trial was conducted with 44 patients, aged 18-65 years, ASA I-III, who were scheduled to undergo arthroscopic knee surgery in our hospital

  • 07 Oct, 2022
  • 1 location