Knee Injuries Clinical Trials

A listing of Knee Injuries medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
I am looking for
added new label for I am looking for
Advanced Filters
Found 130 clinical trials
Study of Efficacy, Safety and Tolerability of DFV890 in Patients With Knee Osteoarthritis

This is a double-blinded, two-arm, phase II study to assess efficacy, safety and tolerability of DFV890 in participants with symptomatic knee osteoarthritis. The study includes a screening period, a treatment period and a follow-up period. At most, the study duration is 21 weeks.

  • 07 Oct, 2022
  • 27 locations
AIR (Artificial Implant to Restore the Medial Meniscus Function)2 Clinical Investigation (AIR2)

The AIR2 Study is a multi-center, prospective, interventional clinical trial with the objective to evaluate the safety and performance of the Trammpolin® medial meniscus prosthesis.

  • 13 Apr, 2022
  • 3 locations
Intramedullary Nailing Versus External Ring Fixation for Surgical Treatment of Tibial Shaft Fractures in Adults and Their One Year Outcome on Recovery: Study Protocol for a Pragmatic Randomized Controlled Trial (The IMVEX Trial) (IMVEX)

This study is a multicenter pragmatic assessor blinded randomized and prospective clinical trial in which standard intramedullary nailing is compared with external ring fixator for patients with tibial shaft fractures.

  • 18 Oct, 2022
  • 3 locations
Comparison of Gait Pattern Between Simultaneous and Staged Knee Arthroplasties

Total knee arthroplasty is a well-known treatment of the end-stage osteoarthritis of the knee. In the case of bilateral end-stage knee osteoarthritis, both of the knees need total knee arthroplasty. Bilateral total knee arthroplasty could be performed simultaneously or staged according to the preference of the patients. Simultaneous total knee …

  • 09 Aug, 2021
  • 1 location
Advanced Cartilage Treatment With Injectable-hydrogel Validation of the Effect (ACTIVE)

Multicentre, pivotal, non-randomized, prospective, open-label clinical investigation involving a new hydrogel, Hy2Care Injectable hydrogel, developed by Hy2Care B.V., Enschede, The Netherlands (hereafter referred to as "Hy2Care") to treat cartilage defects (< 2 cm2) in the human knee. The product aims at functional repair of cartilage defects in the knee and …

  • 10 Mar, 2022
  • 1 location
Comparing Clinical Outcomes of the One-step Cartilage Transplantation in Cartilage Defects of the Knee With Conservative Treatment (IMPACT2)

Articular cartilage defects in the knee have poor intrinsic healing capacity and may lead to functional disability and osteoarthritis. Cartilage cell therapy using autologous chondrocyte implantation has been established as the first advanced treatment therapy medicinal product. Although this technique has achieved good mid-term results, it is a costly and …

  • 24 Feb, 2022
  • 1 location
STaR (Surgical Timing and Rehabilitation) Trial for Multiple Ligament Knee Injuries

personnel and civilians that sustain a multiple ligament knee injury. To achieve this overall objective of this project, we will conduct two parallel randomized clinical trials. For the first study we will

  • 15 Oct, 2022
  • 1 location
Making Football Safer for Women: Implementing an Injury Prevention Program (Prep-to-Play)

The aim of this study is to determine how we can best support coaches to implement an injury prevention (IP) program (Prep-to-Play) in female community Australian Football. We will recruit at least 140 female community football teams from 15 different football leagues in Victoria, Australia. Teams will be competing in …

injury prevention
Accepts healthy volunteers
  • 04 Oct, 2022
  • 1 location
ACL Reconstruction With/Without ALL Reconstruction

This study will compare Anterior Cruciate Reconstruction with or without Anterolateral Ligament Reconstruction in patients with ACL injury. The purpose of this study is evaluate if addition of ALLr to ACLr provides better clinical, radiological and laboratory outcomes.

anterior cruciate ligament reconstruction
acl injuries
Accepts healthy volunteers
  • 04 Oct, 2022
  • 1 location
The Pediatric ALL Evaluation and Trial

The overall aim of this multicenter RCT is to determine whether concomitant ALL reconstruction in children undergoing and ACL reconstruction will longitudinally result in a lower rate of graft failure than ACL reconstruction alone.

  • 07 Aug, 2021
  • 1 location