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Colorectal Cancer Clinical Trials

A listing of Colorectal Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (163) clinical trials

Evaluation of the ctDNA LUNAR Test in an Average Patient Screening Episode

The LUNAR-2 test has been developed to detect malignant disease in screen-relevant patients who would otherwise undergo screening for malignant disease using invasive methodologies such as colonoscopy. The intended use of such a test would be to return a result of ctDNA detected/ ctDNA not detected in a patient eligible …

Phase N/A

Genomic Services Research Program

The implementation of genome and exome sequencing creates challenges and opportunities, particularly with respect to the return of medically-actionable secondary findings (SF). This study seeks to investigate the utility and effectiveness of returning SF generated via research or clinical sequencing by studying individuals who have received such findings. Our objectives …

Phase N/A

Prevention of Colorectal Cancer Through Multiomics Blood Testing

Freenome is using a type of artificial intelligence, called machine learning, to identify patterns of cell-free biomarkers in blood to detect cancer early. The purpose of this prospective multi-center observational study is to validate a blood-based test for the detection of colorectal cancer by collecting blood samples from average-risk participants …

Phase N/A

BESPOKE Study of ctDNA Guided Therapy in Colorectal Cancer

Primary Objectives: Examine the impact of SIGNATERA on adjuvant treatment decisions Determine the rate of recurrence of patients diagnosed with CRC while asymptomatic using SIGNATERA Secondary objectives: Molecular residual disease clearance as assessed by SIGNATERA Percent of patients undergoing surgery for oligometastatic recurrence Survival in patients treated with adjuvant versus …

Phase N/A

Collection of Information to Better Understand Young Onset Colorectal Cancer

The purpose of this registry study is to create a databasea collection of informationfor better understanding young onset colorectal cancer. Colorectal cancer patients are considered to have young onset colorectal cancer if they are diagnosed with their cancer before the age of 50. Researchers will use the information from this …

Phase N/A

Hereditary Gastric Cancer Syndromes: An Integrated Genomic and Clinicopathologic Study of the Predisposition to Gastric Cancer

Background An estimated 1-3% of gastric cancer cases occur within a familial background as part of an inherited cancer syndrome Hereditary Diffuse Gastric Cancer (HDGC) is the most frequent form of familial gastric cancer and has been linked to a germline mutation in the CDH1 gene Gastric Adenocarcinoma and Proximal …

Phase N/A

Rectal Surgery Evaluation Trial (RESET)

The Rectal Surgery Evaluation Trial will be a prospective, observational, case-matched, four-cohort, multicenter trial designed to study TME with LAR using open laparotomy, laparoscopy, robot-assisted surgery, or transanal surgery in high-surgical-risk patients with mid-to-low, non-metastatic rectal cancer. All surgeries will be performed by surgeons experienced in a technique. Oncologic, morbidity …

Phase N/A

Collection of Blood From Patients With Cancer

Background Correlative studies performed on biospecimens of human subjects can be used to investigate the biology of solid tumors, inform the development of new strategies for treating those cancers, and evaluate these new therapeutic approaches. Specific areas of interest include, but are not limited to: the underlying mechanisms of tumor-specific …

Phase N/A

"Wait-and-see" Policy for Complete Responders After Chemoradiotherapy for Rectal Cancer

Standard treatment for patients with locally advanced rectal cancer consists of a long course of (CRT) followed by surgical resection. Although the aim of neoadjuvant treatment in these patients is not organ preservation, but rather to provide improved local control, in the tumour disappears completely. Studies from Maastricht, the UK …

Phase N/A

Short-course Radiotherapy (5 6Gy/7Gy/8Gy) Followed by Neo-adjuvant Chemotherapy for Locally Advanced Rectal Cancer

Rectal cancer is one of the most common malignant tumors in western countries and its incidence and mortality rates have been ascending for several decades in our country. Surgical resection is the primary treatment method for resectable tumor. Post-operative chemo-radiotherapy can improve local control but can also lower the tolerance …

Phase N/A