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Colorectal Cancer Clinical Trials

A listing of Colorectal Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (177) clinical trials

Non-curative ESDs: Assessing the Rates and Risk Factors for Residual Neoplasia

Short and long outcomes of ESD are well described, particularly in Eastern series. However, the outcome of non-curative ESDs is scarcely reported in the west (particularly among non-gastric or submucosal lesions). Therefore, the aim of this project is to describe the European experience with non-curative ESDs, analysing all the consecutive …

Phase N/A

Young-Onset Microsatellite-Stable Colorectal Cancer

Questionnaires If you agree to take part in this study, you will fill out some questionnaires about your work, family history, medical history, and health habits. If you have already answered these questionnaires when you were registered as a patient at MD Anderson, the study staff will give you a …

Phase N/A

Circulating Tumor Cells in Patients With Rectal Cancer

Healthy Participants: If you have not been diagnosed with colorectal cancer, blood (about 2 tablespoons) will be drawn 1 time. This blood will be used as a control (normal) to look for differences in cells in the blood of patients with colorectal cancer. Once your blood is collected, your participation …

Phase N/A

Genomic Services Research Program

The implementation of genome and exome sequencing creates challenges and opportunities, particularly with respect to the return of medically-actionable secondary findings (SF). This study seeks to investigate the utility and effectiveness of returning SF generated via research or clinical sequencing by studying individuals who have received such findings. Our objectives …

Phase N/A

Hereditary Gastric Cancer Syndromes: An Integrated Genomic and Clinicopathologic Study of the Predisposition to Gastric Cancer

Background An estimated 1-3% of gastric cancer cases occur within a familial background as part of an inherited cancer syndrome Hereditary Diffuse Gastric Cancer (HDGC) is the most frequent form of familial gastric cancer and has been linked to a germline mutation in the CDH1 gene Gastric Adenocarcinoma and Proximal …

Phase N/A

Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer

This is a prospective cohort study that examines the impact of myopenia on chemotherapy toxicity in overall survival (OS) in older adults with newly diagnosed metastatic colorectal cancer (CRC) receiving 5-Fluouracil (5FU)systemic chemotherapy. The study also explores the mediating influence of genetic variation in the association between myopenia and chemotherapy …

Phase N/A

BESPOKE Study of ctDNA Guided Therapy in Colorectal Cancer

Primary Objectives: Examine the impact of SIGNATERA on adjuvant treatment decisions Determine the rate of recurrence of patients diagnosed with CRC while asymptomatic using SIGNATERA Secondary objectives: Molecular residual disease clearance as assessed by SIGNATERA Percent of patients undergoing surgery for oligometastatic recurrence Survival in patients treated with adjuvant versus …

Phase N/A

Evaluation of the ctDNA LUNAR Test in an Average Patient Screening Episode

The LUNAR-2 test has been developed to detect malignant disease in screen-relevant patients who would otherwise undergo screening for malignant disease using invasive methodologies such as colonoscopy. The intended use of such a test would be to return a result of ctDNA detected/ ctDNA not detected in a patient eligible …

Phase N/A

Collection of Blood From Patients With Cancer

Background Correlative studies performed on biospecimens of human subjects can be used to investigate the biology of solid tumors, inform the development of new strategies for treating those cancers, and evaluate these new therapeutic approaches. Specific areas of interest include, but are not limited to: the underlying mechanisms of tumor-specific …

Phase N/A

T Helper Cytokines in End Stage Colorectal Cancers

Colorectal cancers are the third most common type of cancer in the world. Peritoneal carcinomatosis and intraabdominal ascites development occur in advanced stages of colorectal cancers. It is known that the immune system plays an important role in tumor development or tumor eradication. Differentiation of T cells towards Th2 and …

Phase N/A