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Colorectal Cancer Clinical Trials

A listing of Colorectal Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found (163) clinical trials

Safety Of ColoRectal Assessment and Tumor Evaluation by Colon Capsule Endoscopy

Following European guidelines patients undergoing colonoscopy in one of Odense University Hospitals units will now be offered a colon capsule endoscopy (CCE) in case of incomplete examinations. Patients formerly referred to colonoscopy in general anesthesia or patients who decline colonoscopy after having completed bowel preparation will also be offered a …

Phase N/A

Feasibility of Non-Operative Management of Rectal Cancer in a Rural Population

Standards of care for patients with rectal cancer are evolving over time. Surgery for rectal cancer is associated with significant short- and long-term side effects for patients, including changes in bowel function, self-image, ability to work, and sexual function. Emerging data indicates that some patients experiencing complete clinical response to …

Phase N/A

A Community-Based Educational Intervention to Improve Colorectal Cancer Screening

PRIMARY OBJECTIVE: I. Develop a culturally tailored colorectal cancer education intervention for underserved and under-represented populations with a focus on African American, Latinx, and Asian (Chinese) in the Sidney Kimmel Cancer Center catchment area. OUTLINE KEY CONTACT INTERVIEWS: Participants participate an interviews over 60 minutes focusing on identifying facilitators and …

Phase N/A

Clinical Study of Gastric Cancer Colorectal Cancer and Bladder Cancer Based on Liquid Biopsy

Gastric cancer and colorectal cancer are common gastrointestinal malignancies in the world.Early cancer generally has no obvious symptoms. Endoscopy is the "gold standard"for the diagnosis of gastric cancer and colorectal cancer.gastric cancer and colorectal cancer treatment mainly includes surgery and medication.Compared with traditional diagnosis and treatment methods, the application of …

Phase N/A

A Clinical Study of Pyrotinib in Patients of Advanced Colorectal Cancer With Her2 Variation

Investigators identified HER2 amplification as a potential onco-driver and marker of de novo resistance to anti-EGFR therapy in mCRC patients for which other known genetic alterations conferring resistance to anti EGFR antibodies were excluded. This study is an open-label Phase II, 2-sequential cohorts trial, assessing the response rate (ORR) of …

Phase N/A

Prevalence of Sleep Apnea in Patients Undergoing Surgery for Colorectal Cancer

Group 1. Inclusion: 200 patients with colorectal cancer scheduled for surgery and 200 controls. Due to drop outs we calculate a need of inviting at least 250 patients with colorectal cancer. We will use controls from an ongoing epidemiological study of sleep apnea in the population. Exclusion: Dementia, CPAP treated …

Phase N/A

Familial Investigations of Childhood Cancer Predisposition

During the study, blood samples or other healthy tissue will be obtained from participants, as well as medical and family histories. When possible, leftover tumor samples will also be collected. If participants agree to be re-contacted in the future, they will be asked about once each year to update their …

Phase N/A

Circulating Tumor DNA Analysis to Optimize Treatment for Patients With Colorectal Cancer

INTRODUCTION Colorectal cancer (CRC) is the third most common cancer worldwide. Approximately two-thirds of patients initially present with potentially curable disease but in spite of curatively intended treatment 30-40% experience relapse of disease. When diagnosed, survival of CRC can basically be improved in two ways, 1) by reducing the risk …

Phase N/A

Donation of Post Mortem Tumor Tissues

Despite the recent technological advancement in genomic and proteomic, the molecular understanding of clonal evolution in solid tumor patients is hampered by intra tumor heterogeneity (ITH), while remaining essential to the effective treatment of patients. Recent evidence suggests that branched evolutionary tumor growth may contribute to ITH both within a …

Phase N/A

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

The SYNERGY Registry is an international prospective, observational cohort study of eligible adult and pediatric pts with advanced solid and hematological malignancies, for whom the decision to consider CTE has already been made by their primary providers (PP). Using a proprietary application programming interface (API) linked to existing electronic health …

Phase N/A