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Colorectal Cancer Clinical Trials

A listing of Colorectal Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (163) clinical trials

"Wait-and-see" Policy for Complete Responders After Chemoradiotherapy for Rectal Cancer

Standard treatment for patients with locally advanced rectal cancer consists of a long course of (CRT) followed by surgical resection. Although the aim of neoadjuvant treatment in these patients is not organ preservation, but rather to provide improved local control, in the tumour disappears completely. Studies from Maastricht, the UK …

Phase N/A

Evaluation of the ctDNA LUNAR Test in an Average Patient Screening Episode

The LUNAR-2 test has been developed to detect malignant disease in screen-relevant patients who would otherwise undergo screening for malignant disease using invasive methodologies such as colonoscopy. The intended use of such a test would be to return a result of ctDNA detected/ ctDNA not detected in a patient eligible …

Phase N/A

Collection of Blood From Patients With Cancer

Background Correlative studies performed on biospecimens of human subjects can be used to investigate the biology of solid tumors, inform the development of new strategies for treating those cancers, and evaluate these new therapeutic approaches. Specific areas of interest include, but are not limited to: the underlying mechanisms of tumor-specific …

Phase N/A

BESPOKE Study of ctDNA Guided Therapy in Colorectal Cancer

Primary Objectives: Examine the impact of SIGNATERA on adjuvant treatment decisions Determine the rate of recurrence of patients diagnosed with CRC while asymptomatic using SIGNATERA Secondary objectives: Molecular residual disease clearance as assessed by SIGNATERA Percent of patients undergoing surgery for oligometastatic recurrence Survival in patients treated with adjuvant versus …

Phase N/A

Short-course Radiotherapy (5 6Gy/7Gy/8Gy) Followed by Neo-adjuvant Chemotherapy for Locally Advanced Rectal Cancer

Rectal cancer is one of the most common malignant tumors in western countries and its incidence and mortality rates have been ascending for several decades in our country. Surgical resection is the primary treatment method for resectable tumor. Post-operative chemo-radiotherapy can improve local control but can also lower the tolerance …

Phase N/A

Collection of Information to Better Understand Young Onset Colorectal Cancer

The purpose of this registry study is to create a databasea collection of informationfor better understanding young onset colorectal cancer. Colorectal cancer patients are considered to have young onset colorectal cancer if they are diagnosed with their cancer before the age of 50. Researchers will use the information from this …

Phase N/A

Ontario-wide Cancer TArgeted Nucleic Acid Evaluation

A recent survey of clinical genetic testing laboratories for cancer diagnostics by the Molecular Oncology Advisory Committee for Cancer Care Ontario identified disparities in access and use patterns for next generation sequencing (NGS) across the province of Ontario. All fourteen responding laboratories indicated that NGS instruments were either currently being …

Phase N/A

Evaluation for NCI Surgery Branch Clinical Research Protocols

Background Potential research candidates undergo thorough screening including laboratory tests, scans, x-rays, and review of pathology slides to determine initial eligibility for National Cancer Institute Surgery Branch (NCI-SB) research protocols. Objectives Permit evaluation of patients referred to the NCI-SB in order to identify individuals who will be suitable candidates for …

Phase N/A

CIRSE Registry for LifePearl Microspheres

CIREL will capture a broad spectrum of real clinical data on the delivery of transcatheter arterial chemoembolisation (TACE) using LifePearl Microspheres loaded with Irinotecan (LP-IRI) and the observed clinical outcomes. The aim of doing so is to improve our understanding of how LifePearl microspheres are administered as part of the …

Phase N/A

Intracorporeal Anastomosis in Laparoscopic Left Colectomy. Cohort Comparative Study

HYPOTHESIS Resection of the left colon / sigmoid with intracorporeal colorectal TT anastomosis is safe and not inferior to that performed extracorporeally. With the benefits of reduced intraoperative dissection, traction on the mesenteries, reduced vascular compromise of the anastomosis, a smaller incision size and being able to choose its location. …

Phase N/A