Colorectal Cancer Clinical Trials

A listing of Colorectal Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 1516 clinical trials
Use of a Distal Colonoscope Attachment to Increase Detection of Sessile Serrated Adenomas

This study evaluates whether the use of a disposable colonoscope attachment, Endocuff Vision, can increase the detection of sessile serrated adenomas. Participating patients will be randomized to receive either standard colonoscopy or colonoscopy with the Endocuff Vision.

  • 24 Sep, 2021
Circulating Tumour DNA Based Decision for Adjuvant Treatment in Colon Cancer Stage II Evaluation

The CIRCULATE study evaluates the adjuvant therapy in patients with colon cancer UICC stage II. The primary aim of the study is to compare the disease free survival in patients who are positive for postoperative circulating tumour DNA with vs. without capecitabine.

  • 24 Jan, 2021
A Trial on Prophylactic Clipping to Prevent Post-polypectomy Bleeding After Colonoscopy in Direct Oral Anticoagulant Users (PROCLIP)

The investigators hypothesize that prophylactic clipping after colonoscopic polypectomy can reduce risk of delayed PPB among DOAC users. The investigators also hypothesize that pre-endoscopy drug level can predict the risk of hemorrhagic complications after the procedure.

  • 09 Apr, 2022
  • 1 location
Perioperative Iron for Colorectal Cancer (PICoC Study) (PICoC)

The PICoC study aims to investigate whether oral ferric maltol given postoperatively offers an improvement in patient and clinician reported outcomes compared to standard care.

  • 11 Jul, 2022
  • 1 location
TACE Plus Axitinib and Hydroxychlorquine for Liver-Dominant Metastatic Colorectal Cancer (CRC) (TACE-Ax-HCQ)

Liver metastases are a leading cause of death among patients with metastatic colorectal cancer. Duration of disease control is short following 2nd-line or later systemic therapy. Liver-directed

  • 11 May, 2022
  • 1 location
Dabrafenib + Trametinib + PDR001 In Colorectal Cancer

This research study is studying a combination of drugs as a possible treatment for metastatic colorectal cancer characterized by BRAF V600E mutation. The names of the study drugs involved

neutrophil count
spiral computed tomography
measurable disease
ct scan
  • 09 Jul, 2022
  • 2 locations
Fruquintinib as a Maintenance Therapy Following First-line Treatment for Metastatic Colorectal Cancer

metastatic colorectal cancer. This study will include the patients with confirmed unresectable metastatic left-sided colon cancer with RAS mutation or right-sided colon cancer who achieved stable disease (SD

  • 15 Nov, 2021
  • 1 location
Safety Study of Transumbilical Single Incision Versus Conventional Laparoscopic Surgery for Colorectal Cancer

because of its reduced incision-associated morbidity and scarring. However, the safety and efficacy of single incision laparoscopic surgery for colorectal cancer has not yet been

  • 08 Nov, 2020
  • 1 location
A Dose Escalation Study of APR003 in Patients With Advanced Colorectal Cancer (CRC) With Malignant Liver Lesions

A Phase 1 dose escalation study to evaluate APR003 in patients with advanced colorectal cancer (CRC) with malignant liver lesions

  • 10 May, 2021
  • 4 locations
Immunotherapy for Third Line Metastatic Colorectal Cancer

This is a Phase IIB multi-site, open label study of a next generation immunotherapy for third-line MSI-S metastatic colorectal cancer using an "off-the-shelf", non-genetically manipulated living

  • 22 Sep, 2021
  • 3 locations