Colorectal Cancer Clinical Trials

A listing of Colorectal Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 1505 clinical trials
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HPV Vaccine PRGN-2009 Alone or in Combination With Anti-PDL1/TGF-Beta Trap (M7824) in Subjects With HPV Associated Cancers

Background For some cancers associated with human papillomavirus (HPV), standard treatments are not helpful. Researchers want to see if a vaccine for HPV combined with a drug called M7824 has a better effect on these cancers than when they work alone. Objective To find a safe dose of HPV vaccine …

squamous cell carcinoma
antiretrovirals
solid tumors
liver metastases
atezolizumab
  • 0 views
  • 27 Sep, 2021
  • 1 location
None
RTX-321 Monotherapy in Patients With HPV 16+ Tumors

This is an open-label, multicenter, multiple-ascending dose, FIH, Phase 1 study of RTX-321 for the treatment of patients that are HLA-A*02:01 positive with persistent, recurrent, or metastatic, unresectable, HPV 16+ cancers.

growth factor
mitomycin
bevacizumab
mitomycin c
platelet count
  • 0 views
  • 01 Oct, 2021
  • 9 locations
None
Efficacy of Immunotherapy Plus a Drug in Patients With Progressive Advanced Mucosal Cancer of Different Locations

Interventional study evaluating the efficacy of an immunotherapy (pembrolizumab) in combination with a targeted therapy (vorinostat) in patient with recurrent and/or metastatic squamous cell carcinoma (localisations : head and neck, lung, cervix, anus, vulva, and penis)

measurable disease
squamous cell carcinoma
aptt
anticoagulant
carcinoma
  • 0 views
  • 27 Jun, 2021
  • 14 locations
None
Detecting HPV DNA in Anal and Cervical Cancers

This is a research study for individuals who have cancer associated with human papillomavirus (HPV) and are being treated with radiation as part of standard care for their cancer. Doctors leading this study will use blood tests to find out if they can detect the HPV virus in the blood …

diagnostic procedures
human papilloma virus vaccine
human papillomavirus dna
human papillomavirus
x-rays
  • 0 views
  • 23 Jun, 2021
  • 1 location
None
Assessment of Patients' Quality of Sexual Life After Anal Cancer Treatment

The purpose of this this study, to evaluate the quality of sexual life of patients treated for anal cancer treated by radiotherapy, during their treatment, then 3 months after treatment and, finally, 2 years after treatment. cancer diagnosis.

  • 0 views
  • 13 Nov, 2021
  • 1 location
None
Survivin Peptide Vaccination for Patients With Advanced Melanoma Pancreatic Colon and Cervical Cancer

This study evaluates the safety, the immunological response and the clinical outcome of a vaccination with survivin peptides for patients with advanced melanoma, pancreatic, colon and cervical carcinoma.

peptide vaccine
cervical carcinoma
vaccination
carcinoma
advanced melanoma
  • 37 views
  • 07 Nov, 2020
  • 1 location
None
Pharmacokinetic and Pharmacodynamic Study of S-1 in Patients With Digestive Organ Cancer

S-1 is a novel oral fluorouracil antitumor drug that consists of tegafur which is a prodrug of 5-fluorouracil (5-FU); 5-chloro-2,4-dihydropyridine (CDHP), which inhibits dihydropyrimidine dehydrogenase (DPD) activity; and potassium oxonate (Oxo), which reduces gastrointestinal toxicity. 5-FU is metabolized by CYP2A6 and DPD. In this study, the researchers investigate the influences …

gimeracil
potassium
tegafur
fluorouracil
cancer
  • 7 views
  • 07 Nov, 2020
  • 1 location
None
Vaccine Therapy in Treating Patients With Metastatic Solid Tumors

This phase I trial studies the side effects and best dose of vaccine therapy in treating patients with metastatic solid tumors. Vaccines made from antibodies and peptides combined with tumor cells may help the body build an effective immune response to kill tumor cells.

cancer chemotherapy
monoclonal antibodies
epidermal growth factor
platelet count
mammogram
  • 30 views
  • 03 Nov, 2021
  • 1 location
None
Measuring the Impact of Low Radiotherapy Doses on Bone Marrow

Bone marrow is one of the organs at risk of complications during irradiation due to its radiosensitivity. Hematopoietic toxicity remains one of the main toxicities during irradiation of pelvic lymph node areas, especially when concomitant chemotherapy is used, volume of bone marrow irradiated is large and dose to the bone …

  • 0 views
  • 26 Jan, 2021
  • 1 location
None
Multimodal Monitoring of Radiotherapy Response in Squamous Cell Cancer

The study's aim is to define imaging and molecular bio-markers for prediction of radiotherapy response of squamous cell carcinomas, in an early treatment phase.

squamous cell carcinoma
cavities
carcinoma
dental caries
medical therapy
  • 29 views
  • 09 Oct, 2021
  • 3 locations