Colorectal Cancer Clinical Trials

A listing of Colorectal Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 519 clinical trials
Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors

The investigational drug to be studied in this protocol, BCA101, is a first-in-class compound that targets both EGFR with TGFβ. Based on preclinical data, this bifunctional antibody may exert synergistic activity in patients with EGFR-driven tumors.

measurable disease
KRAS
ki-ras
carcinoma
experimental drug
  • 11 views
  • 25 Jul, 2022
  • 8 locations
Infusion System for Hepatic Cancer

biopsy-proven diagnosis of colorectal cancer metastatic to the liver or intrahepatic cholangiocarcinoma. After successful implantation, the combined pump and catheter system will be evaluated

cancer
  • 0 views
  • 24 Jul, 2022
  • 1 location
Well-being and Stress Control After Colorectal Surgery (C-Bien)

colorectal cancer by offering stress management sessions in order to promote postoperative rehabilitation. The secondary objectives are to demonstrate the impact of stress management sessions on the

cancer surgery
cancer
postoperative complication
  • 0 views
  • 20 Jul, 2022
  • 1 location
Adoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid Cancers

This is a Phase 2 study to evaluate the efficacy of a non-myeloablative lymphodepleting preparative regimen followed by infusion of autologous TIL and high-dose aldesleukin in patients with locally advanced, recurrent, or metastatic cancer associated with one of the following cancer types: 1.) gastric/esophagogastric, 2.) colorectal, 3.) pancreatic, 4.) sarcoma, …

fludarabine
sarcoma
immunosuppressive
cancer
alt/ast
  • 12 views
  • 08 Jun, 2022
  • 1 location
Liposomal Irinotecan, Fluorouracil, Leucovorin Calcium, and Rucaparib in Treating Patients With Metastatic Pancreatic, Colorectal, Gastroesophageal, or Biliary Cancer

This phase I/II trial studies the side effects and best dose of liposomal irinotecan and rucaparib when given together with fluorouracil and leucovorin calcium and to see how well they work in treating patients with pancreatic, colorectal, gastroesophageal, or biliary cancer that has spread to other places in the body …

measurable disease
parp inhibitor
oophorectomy
tumor cells
cancer
  • 8 views
  • 16 Jun, 2022
  • 3 locations
IBD Neoplasia Surveillance Pilot RCT (IBDDysplasia)

To determine if random biopsies can be safely eliminated from screening of average risk persons with IBD, the investigators propose to carry out a pilot randomized control trial in which targeted biopsies in combination with random biopsies will be compared to targeted biopsies alone in terms of pre-cancerous lesion capture …

remission
colitis
enteropathy
primary sclerosing cholangitis
crohn's disease
  • 1 views
  • 11 May, 2022
  • 11 locations
Pre-Habilitation Exercise Intervention

The purpose of this study is to see whether exercise can improve the health and well-being of patients scheduled to undergo surgery for a bowel related condition.

enteropathy
cancer
rectal carcinoma
  • 3 views
  • 02 Jun, 2022
  • 1 location
M6620 and Irinotecan Hydrochloride in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

This phase I trial studies the side effects and best dose of M6620 and irinotecan hydrochloride in treating patients with solid tumors that have spread to other places in the body (metastatic) or cannot be removed by surgery (unresectable). M6620 and irinotecan hydrochloride may stop the growth of tumor cells …

ct scan
measurable disease
m6620
line of therapy
tumor cells
  • 31 views
  • 12 Jul, 2022
  • 7 locations
Safety and Effectiveness of Eye90 Microspheres™ in the Treatment of Unresectable HCC and mCRC

The purpose of this study is to evaluate the safety of treatment with Eye90 microspheres in patients with unresectable Hepatocellular Carcinoma (HCC) and metastatic Colorectal Cancer (mCRC

  • 0 views
  • 04 Jun, 2022
  • 1 location
Combining Epigenetic And Immune Therapy to Beat Cancer. (CAIRE)

Umbrella study structure to independently and simultaneously assess the effects of the association of durvalumab and tazemetostat in multiple solid tumors.

  • 0 views
  • 17 Jun, 2022
  • 2 locations