Colorectal Cancer Clinical Trials

A listing of Colorectal Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 540 clinical trials
Colorectal Health Research Champions

The purpose of the Colorectal Health Research Champions program is to provide accurate and reliable colorectal health cancer information that they can share within their communities to encourage cancer prevention, screening, and early detection, as well as the importance of participating in research.

Accepts healthy volunteers
  • 0 views
  • 11 May, 2022
  • 1 location
Living Donor Liver Transplantation With Two Stage Hepatectomy for Patients With Isolated, Irresectable Colorectal Liver Metastases (LIVERT(W)OHEAL)

Nearly one third of patients with colorectal cancer develop liver metastases. It is well known that the achievement of a R0-situation is one of the most important factors for a positive long

metastasis
hepatectomy
carcinoma
tumor burden
liver metastasis
  • 31 views
  • 24 Apr, 2022
  • 2 locations
Tucatinib Plus Trastuzumab and Oxaliplatin-based Chemotherapy or Pembrolizumab-containing Combinations for HER2+ Gastrointestinal Cancers

This trial studies tucatinib to find out if it is safe when given with trastuzumab and other anti-cancer drugs (pembrolizumab, FOLFOX, and CAPOX). It will look at what side effects happen when participants take this combination of drugs. A side effect is anything the drug does other than treating cancer. …

measurable disease
gastric adenocarcinoma
erbb2
fluorouracil
adenocarcinoma
  • 36 views
  • 10 Aug, 2022
  • 15 locations
Surufatinib in Combination With Tislelizumab in Subjects With Advanced Solid Tumors

This open-label, phase Ib/II study of surufatinib in combination with tislelizumab will evaluate the safety, tolerability, PK and efficacy in patients with advanced solid tumors. The study consists of 2 parts - dose finding (Part 1) and dose expansion (Part 2).

systemic therapy
cancer
cancer chemotherapy
adenocarcinoma
BRAF
  • 2 views
  • 26 Apr, 2022
  • 16 locations
A Study of ELI-002 in Subjects With KRAS Mutated Pancreatic Ductal Adenocarcinoma (PDAC) and Other Solid Tumors (AMPLIFY-201)

This is a Phase 1 study to assess the safety and efficacy of ELI-002 immunotherapy (a lipid-conjugated immune-stimulatory oligonucleotide [Amph-CpG-7909] plus a mixture of lipid-conjugated peptide-based antigens [Amph-Peptides]) as adjuvant treatment of minimal residual disease (MRD) in subjects with KRAS/neuroblastoma ras viral oncogene homolog (NRAS) mutated PDAC or other solid …

KRAS
NRAS
cancer chemotherapy
  • 12 views
  • 27 Jul, 2022
  • 8 locations
JAB-21822 in Combination With Cetuximab in Patients With Advanced CRC and Other Solid Tumors With KRAS G12C Mutation

This study is to evaluate the safety, tolerability, pharmacokinetics and antitumor activity of JAB-21822 in combination with cetuximab in patients with advanced colorectal cancer,advanced small

  • 0 views
  • 23 Apr, 2022
EMB-01 in Patients With Advanced/Metastatic Gastrointestinal Cancers

colorectal cancer.

measurable disease
biological factors
hormone therapy
tyrosine
bone metastases
  • 0 views
  • 06 May, 2022
  • 4 locations
R vs L Lateral Decubitus Positioning in Colonoscopy

Colonoscopy continues to be the gold standard in detecting precancerous lesions in the colon. It relies on adequate visualization of the bowel wall to see and remove such lesions. Visualization is improved with luminal distention, and a multitude of studies have been done to determine ways to increase this luminal …

adenoma
Accepts healthy volunteers
luminal
  • 14 views
  • 27 Apr, 2022
  • 1 location
Assessing How the Viscosity of Submucosal Gel Injections Helps With Endoscopic Mucosal Resections

This is a study to determine how the viscosity (thickness) of an FDA approved gel affects the ease in which endoscopic mucosal resections (EMR) can be performed.

gastrectomy
colectomy
  • 3 views
  • 26 Apr, 2022
  • 1 location
Endoscopic Full Thickness Resection Versus Standard Therapy of the Colorectal Neoplasia

Most of the cancers develop from the adenomatous polyps. The therapeutic methods have been established already - endoscopic polypectomy (EPE) for stalked polyps and endoscopic mucosal resection (EMR) or endoscopic submucosal dissection (ESD) for non-pedunculated polyps. EMR is preferred in European countries over ESD because of its higher feasibility. However, …

  • 0 views
  • 03 May, 2022
  • 1 location