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Chemotherapy Clinical Trials

A listing of Chemotherapy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (37) clinical trials

Precision Cell Immunotherapy Combined With Chemotherapy in Advanced Gastric Cancer

A total of 40 patients may be enrolled over a period of 1-2 years.

Phase

Precision Cell Immunotherapy Combined With Chemotherapy in Advanced Gastric Cancer

A total of 40 patients may be enrolled over a period of 1-2 years.

Phase

Pilot Study of Anti-CD20-CAR-engineered T Cells in Patients With Chemotherapy Resistant or Refractory CD20+ Lymphoma

Chimeric antigen receptor (CAR) T cells targeting CD20 will be evaluated for safety and efficacy in patients with CD20+ B cell lymphoma. The CAR consists of a CD20 targeting antibody scFv with two intracellular signaling domains derived from CD3 zeta and CD28. Autologous T cells will be gene-engineered with the ...

Phase

Enzalutamide With and Without Ribociclib for Metastatic Castrate-Resistant Chemotherapy-Naive Prostate Cancer That Retains RB Expression

PRIMARY OBJECTIVES: I. To determine the maximum tolerated dose of ribociclib in combination with 160 mg of enzalutamide. (Phase Ib) II. To determine efficacy with respect to the proportion of subjects that achieve a >= 50% reduction in prostate-specific antigen (PSA) at 12 weeks. (Phase II) SECONDARY OBJECTIVES: I. PSA ...

Phase

Intra-arterial Chemotherapy for Children With Retinoblastoma

Retinoblastoma is a cancer of the eye that occurs exclusively in children. The treatment for retinoblastoma may include surgery, chemotherapy, radiation and local treatments to the eye such as freezing (cryotherapy) and local radiation (brachytherapy). In some cases, a child with retinoblastoma will have active cancer in a single remaining ...

Phase

Activity of Regorafenib in Combination With Chemotherapy in Patients With Advanced Biliary Tract Cancer

Regorafenib (BAY 73-4506) was assessed in metastatic colorectal cancer in the phase III randomized CORRECT trial. 760 metastatic colorectal cancer patients were recruited after the failure of all standard therapies. Given the promising efficacy and favorable tolerability profile of mGEMOX and the potential benefits of targeting the VEGF and Ras/Raf ...

Phase

A Safety and Efficacy Study of INC280 Alone and in Combination With Erlotinib Compared to Chemotherapy in Advanced/Metastatic Non-small Cell Lung Cancer Patients With EGFR Mutation and cMET Amplification

The purpose of this study is to determine the maximum tolerated dose (MTD) or recommended phase II dose (RP2D) of INC280 in combination with erlotinib in the Phase Ib of this study, and to assess the anti-tumor activity and safety of INC280 alone, and in combination with erlotinib, versus platinum ...

Phase

D-CIK Combined With Chemotherapy for Non-Small Cell Lung Cancer(NSCLC)

60 patients with stage b NSCLC will be randomly divided into group Areceive D-CIK treatment and chemotherapy) or group Bjust receive chemotherapy),and the randomize ratio will be 1:1. Patients in group A will receive 3 cycles of D-CIK treatment (every 1 months) and 4 cycles of chemotherapy (every 2 weeks).Patients ...

Phase

Precision Cell Immunotherapy Combined With TACE in Advanced Liver Cancer

A total of 40 patients may be enrolled over a period of 1-2 years.

Phase

Precision Cell Immunotherapy Combined With Chemotherapy in Advanced Lung Cancer

A total of 40 patients may be enrolled over a period of 1-2 years.

Phase