Chemotherapy Clinical Trials

A listing of Chemotherapy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 1674 clinical trials
A Randomized Phase III Trial Comparing Conventional-Dose Chemotherapy Using Paclitaxel, Ifosfamide, and Cisplatin (TIP) With High-Dose Chemotherapy Using Mobilizing Paclitaxel Plus Ifosfamide Followed by High-Dose Carboplatin and Etoposide (TI-CE) as First Salvage Treatment in Relapsed or Refractory Germ Cell Tumors

This randomized phase III trial studies how well standard-dose combination chemotherapy works compared to high-dose combination chemotherapy and stem cell transplant in treating patients with

g-csf
cancer chemotherapy
tumor markers
cancer
testicular
  • 907 views
  • 16 Oct, 2022
  • 91 locations
  • 0 views
  • 22 Oct, 2022
  • 1 location
Multicentric Phase II-III Study Evaluating the Tailored Management of Locally-advanced Rectal Carcinoma After a Favorable Response to Induction Chemotherapy (GRECCAR14)

according to the early tumoral response after short and intensive induction chemotherapy. MRI volumetric tumor response will be used to distinguish between good responders and bad responders. "Very

oxaliplatin
proctectomy
irinotecan
total mesorectal excision
capecitabine
  • 0 views
  • 23 Oct, 2022
  • 14 locations
Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

This phase III trial studies whether inotuzumab ozogamicin added to post-induction chemotherapy for patients with High-Risk B-cell Acute Lymphoblastic Leukemia (B-ALL) improves outcomes. This

mercaptopurine
cancer chemotherapy
b-cell acute lymphoblastic leukemia
dexamethasone
pegaspargase
  • 56 views
  • 04 Oct, 2022
  • 120 locations
A Phase 1b Study of ZN-c3 in Combination With Chemotherapy in Patients With Platinum-Resistant Ovarian, Peritoneal or Fallopian Tube Cancer

This is a Phase 1b open-label, multicenter study, evaluating the safety, tolerability, preliminary clinical activity, pharmacokinetics (PK), and pharmacodynamics of ZN-c3 in combination with other drugs.

doxorubicin
carboplatin
gemcitabine
ovarian cancer
cancer of the ovary
  • 4 views
  • 17 Oct, 2022
  • 15 locations
Minimally Invasive Surgery After Neoadjuvant Chemotherapy for the Treatment of Stage IIIC-IV Ovarian, Primary Peritoneal, or Fallopian Tube Cancer, LANCE Trial

chemotherapy before and after surgery (neoadjuvant chemotherapy). MIS is a surgical procedure that uses small incision(s) and is intended to produce minimal blood loss and pain for the patient. Laparotomy is a

  • 0 views
  • 04 Oct, 2022
  • 1 location
A Phase 3 Trial Investigating Blinatumomab (NSC# 765986) in Combination With Chemotherapy in Patients With Newly Diagnosed Standard Risk or Down Syndrome B-Lymphoblastic Leukemia (B-ALL) and the Treatment of Patients With Localized B-Lymphoblastic Lymphoma (B-LLy)

This phase III trial studies how well blinatumomab works in combination with chemotherapy in treating patients with newly diagnosed, standard risk B-lymphoblastic leukemia or B-lymphoblastic

mercaptopurine
b-cell acute lymphoblastic leukemia
dexamethasone
pegaspargase
combination chemotherapy
  • 92 views
  • 27 Oct, 2022
  • 120 locations
A Phase II Study of Adjuvant PALbociclib as an Alternative to CHemotherapy in Elderly patientS With High-risk ER+/HER2- Early Breast Cancer (Appalaches)

Phase II study to assess the efficacy of the combination of at least 5 year endocrine therapy and 2 year-palbociclib as adjuvant systemic treatment instead of adjuvant chemotherapy followed by

adjuvant chemotherapy
bilateral breast cancer
estrogen receptor
anthracyclines
endocrine therapy
  • 4 views
  • 16 Oct, 2022
  • 77 locations
Phase II/III Study of Circulating Tumor DNA as a Predictive Biomarker in Adjuvant Chemotherapy in Patients With Stage IIA Colon Cancer (COBRA)

, and those who do not benefit, from receiving chemotherapy.

fluorouracil
cancer
international normalized ratio
tumor cells
absolute neutrophil count
  • 0 views
  • 23 Oct, 2022
  • 627 locations
International Phase 3 Trial in Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph+ALL) Testing Imatinib in Combination With Two Different Cytotoxic Chemotherapy Backbones

This randomized phase III trial studies how well imatinib mesylate works in combination with two different chemotherapy regimens in treating patients with newly diagnosed Philadelphia chromosome

b-cell acute lymphoblastic leukemia
dexamethasone
pegaspargase
anthracycline
methotrexate
  • 310 views
  • 12 Oct, 2022
  • 168 locations