Human Papilloma Virus (HPV) Clinical Trials

A listing of Human Papilloma Virus (HPV) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 13 clinical trials
Cemiplimab and ISA101b Vaccine in Adult Participants With Recurrent/Metastatic Human Papillomavirus (HPV)16 Cervical Cancer Who Have Experienced Disease Progression After First Line Chemotherapy

The primary objective of the study is to estimate the clinical benefit of cemiplimab + ISA101b after progression on first line chemotherapy, as assessed by objective response rate (ORR). The secondary objectives of the study are: To characterize the safety profile of cemiplimab + ISA101b To assess preliminary efficacy of …

human papillomavirus
measurable disease
human papilloma virus vaccine
  • 18 Jul, 2021
  • 25 locations
Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer

overall survival (time being alive) and progression-free survival (time being alive without cancer) for patients with intermediate risk human papillomavirus (HPV) positive oropharynx cancer (throat cancer

  • 30 Jul, 2021
  • 540 locations
De-intensified Radiation Therapy With Chemotherapy (Cisplatin) or Immunotherapy (Nivolumab) in Treating Patients With Early-Stage HPV-Positive Non-Smoking Associated Oropharyngeal Cancer

This phase II/III trial studies how well a reduced dose of radiation therapy works with nivolumab compared to cisplatin in treating patients with human papillomavirus (HPV)-positive

chemotherapy regimen
tumor cells
head and neck cancer
pet-ct scan
  • 30 Jul, 2021
  • 228 locations
Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug Atezolizumab to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer

This phase II/III trial studies how well radiation therapy works when given together with cisplatin, docetaxel, cetuximab, and/or atezolizumab after surgery in treating patients with high-risk stage III-IV head and neck cancer the begins in the thin, flat cells (squamous cell). Specialized radiation therapy that delivers a high dose of …

absolute neutrophil count
gilbert's syndrome
  • 31 Jul, 2021
  • 139 locations
Self-sampling for Human Papillomavirus (HPV) Among Patients Receiving Colposcopy

This study seeks to compare the accuracy and acceptability of HPV testing self-sampling kit and standard clinician-sampling for HPV testing. The primary outcome of this study is the concordance between screening results on self-sampling kits compared to clinician-collected HPV test, Pap smear results, and colposcopy. Secondary endpoints will include acceptability …

  • 17 Jul, 2021
  • 1 location
Safety and Efficacy of KITE-439 in HLA-A*02:01+ Adults With Relapsed/Refractory HPV16+ Cancers

Phase 1B is to estimate the efficacy of KITE-439 in human leukocyte antigen (HLA)-A*02:01+ adults with relapsed/refractory human papillomavirus (HPV)16+ cancers.

  • 27 Jul, 2021
  • 8 locations
Radiation Therapy and Cisplatin With or Without Cetuximab in Treating Patients With HPV Positive KRAS-Variant Stage III-IV Oropharyngeal Squamous Cell Carcinoma

This phase II trial studies how well radiation therapy and cisplatin with or without cetuximab works in treating patients with human papillomavirus (HPV) positive, KRAS-variant stage III-IV

  • 24 Jul, 2021
  • 1 location
E7 TCR T Cells for Human Papillomavirus-Associated Cancers

Background Human papillomavirus (HPV) can cause cervical, throat, anal, and genital cancers. Cancers caused by HPV have a HPV protein called E7 inside of their

white blood cells
absolute neutrophil count
chemotherapy regimen
hpv vaccine
  • 29 Jul, 2021
  • 1 location
Combination of UCPVax Vaccine and Atezolizumab for the Treatment of Human Papillomavirus Positive Cancers (VolATIL)

70% all cases of cervical cancer, 95% of anal cancers and about 70% of oropharyngeal cancers are linked to Human Papillomavirus (HPV) infection. HPV oncogenic proteins are trans-activators of

head and neck carcinoma
cytotoxic chemotherapy
cancer vaccine
  • 31 Jul, 2021
  • 4 locations
Optimising Radiation Therapy in Head and Neck Cancers Using Functional Image-Guided Radiotherapy and Novel Biomarkers

This is a non-randomised study to develop personalised treatment approaches in participants with Locally Advanced Head and Neck Cancer (HNC) of the oropharynx and base of skull by integrating the use of MR-guided Adaptive Radiotherapy (MRgRT) and functional image-guided radiotherapy (FIgRT). The study is made up of two parts: Feasibility …

head and neck carcinoma
advanced head and neck carcinoma
  • 28 Jul, 2021
  • 1 location