Anal Dysplasia Clinical Trials

A listing of Anal Dysplasia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 393 clinical trials
Safety and Efficacy of KY1044 and Atezolizumab in Advanced Cancer

A Phase 1/2, open label, multi-center study to evaluate the safety, efficacy and tolerability of KY1044 as single agent and in combination with anti-PD-L1 (atezolizumab) in adult patients with selected advanced malignancies, who are ineligible for or there are no available therapies known to confer a clinical benefit for their …

measurable disease
squamous cell carcinoma
solid neoplasm
monoclonal antibodies
pd-l1
  • 89 views
  • 06 Jul, 2021
  • 11 locations
A Safety Study of SEA-TGT (SGN-TGT) in Advanced Cancer

This trial will look at a drug called SEA-TGT (also known as SGN-TGT) to find out whether it is safe for patients with solid tumors and lymphomas. It will study SEA-TGT to find out what its side effects are. A side effect is anything the drug does besides treating cancer. …

t-cell lymphoma
brentuximab
stem cell transplantation
pembrolizumab
solid tumor
  • 2 views
  • 19 Jul, 2021
  • 13 locations
PDT Plus Vitamin D3 for Anal Dysplasia

This is a phase I dose escalation study of photodynamic therapy (PDT) for the treatment of patients with pre-malignant tumors and superficial microinvasive disease of the anal canal and/or perianal skin. All subjects (a maximum of 12) will be given the photosensitizer ALA orally followed by the administration of red …

squamous cell carcinoma
photosensitizer
photodynamic therapy
anal canal
cancer
  • 60 views
  • 25 Jan, 2021
  • 1 location
Role of Intravenous Lipid Emulsion in Improving Coma of Acute Antipsychotics Poisoning

Intravenous Lipid Emulsion in Improving Coma Of Antipsychotic drugs Acute Poisoning: A Randomized Controlled Trial in Poison Control Center of Ain Shams University Hospitals

  • 0 views
  • 27 Mar, 2021
  • 1 location
Biospecimen Collection and Testing for the Prevalence of Anal Dysplasia and Anal Cancer in Patients With Cervical Vaginal and Vulvar Dysplasia and Cancer

This trial studies the prevalence of anal dysplasia and anal cancer in patients with cervical, vaginal, and vulvar dysplasia and cancer. Studying samples collected from patients in the

squamous cell carcinoma
cancer
hsil
carcinoma
adenocarcinoma
  • 96 views
  • 26 Jan, 2021
  • 1 location
VGX-3100 and Electroporation in Treating Patients With HIV-Positive High-Grade Anal Lesions

This phase II trial studies the use of human papillomavirus (HPV) deoxyribonucleic acid (DNA) plasmids therapeutic vaccine VGX-3100 (VGX-3100) and electroporation in treating patients with human immunodeficiency virus (HIV)-positive high-grade anal lesions. Vaccines made from DNA may help the body build an effective immune response to kill tumor cells. Electroporation …

hysterectomy
therapeutic vaccine
hiv diagnosis
antiretroviral
oophorectomy
  • 5 views
  • 07 Mar, 2021
  • 5 locations
Immunogenicity and Safety of a 9-valent Human Papillomavirus Vaccine in HIV-positive Women

adult women living with HIV will produce antibodies against nine genotypes of HPV, thus preventing the acquisition of new infections by those genotypes. Besides, this will prevent the cervical and anal

hpv vaccine
human papillomavirus
HIV Vaccine
  • 15 views
  • 24 Jan, 2021
  • 1 location
Screening for Anal Cancer in Women With High-grade Vulvar Dysplasia or Vulvar Cancer.

Almost half of all women will develop an HPV infection in their lifetime. While most infections are naturally asymptomatic or cleared by the immune system, some persist and can lead to the development of cervical, vulvar, or anal lesions and eventually cancer. Screening regimens for these lesions are currently only …

smear
PAP test
dysplasia
anal pap smear
cancer
  • 0 views
  • 25 May, 2021
  • 1 location
Imiquimod Fluorouracil or Observation in Treating HIV-Positive Patients With High-Grade Anal Squamous Skin Lesions

This randomized phase III trial studies imiquimod or fluorouracil to see how well they work compared to observation in treating patients with high-grade anal squamous skin lesions who are human immunodeficiency virus (HIV)-positive. Biological therapies, such as imiquimod, may stimulate the immune system in different ways and stop tumor cells …

antibody test
immunodeficiency
enzyme-linked immunosorbent assay
antiretroviral
self-administration
  • 29 views
  • 10 Apr, 2021
  • 13 locations
Tavo and Pembrolizumab With or Without Chemotherapy in Patients With Inoperable Locally Advanced or Metastatic TNBC

This is a Phase 2, Multi-Cohort, Open-Label, Multi-Center Study. Cohort 1 will be a single-arm study of intratumoral tavokinogene telseplasmid (tavo) plus electroporation (EP) in combination with pembrolizumab therapy. Cohort 2 will be a single-arm study of intratumoral tavo-EP plus pembrolizumab with nab-paclitaxel (Abraxane) chemotherapy. Subjects with TNBC and EP …

erbb2
serum pregnancy test
measurable disease
epidermal growth factor
progesterone
  • 27 views
  • 11 May, 2021
  • 7 locations