Anal Dysplasia Clinical Trials

A listing of Anal Dysplasia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 393 clinical trials
Study Assessing the Efficacy and Safety of Alpelisib + Nab-paclitaxel in Subjects With Advanced TNBC Who Carry Either a PIK3CA Mutation or Have PTEN Loss

The purpose of this study is to determine whether treatment with alpelisib in combination with nab-paclitaxel is safe and effective in subjects with advanced triple negative breast cancer (aTNBC) who carry either a PIK3CA mutation (Study Part A) or have PTEN loss (Study Part B1) or PTEN loss without PIK3CA …

breast cancer
measurable disease
paclitaxel
metastasis
PTEN
  • 5 views
  • 14 Jul, 2021
  • 152 locations
A Study of AL101 Monotherapy in Patients With Notch Activated Triple Negative Breast Cancer

The current study is designed to evaluate the efficacy and safety of AL101 monotherapy in subjects with Notch-activated recurrent or metastatic TNBC; Notch activation will be determined by a Next Generation Sequencing (NGS) test.

breast cancer
progesterone
measurable disease
formalin-fixed paraffin-embedded
parp inhibitor
  • 0 views
  • 03 Jun, 2021
  • 27 locations
Clinical Trial of Neoadjuvant Chemotherapy With Atezolizumab or Placebo in Patients With Triple-Negative Breast Cancer Followed After Surgery by Atezolizumab or Placebo

The main purpose of this study is to learn if the usual chemotherapy given before surgery (neoadjuvant therapy) for breast cancer plus the experimental drug, atezolizumab, is better than the usual chemotherapy plus a placebo. (A placebo is a drug that looks like the study drug but contains no medication.) …

adenocarcinoma
carboplatin
her2/neu-negative breast cancer
programmed cell death 1 ligand 1
mammogram
  • 1000 views
  • 21 Apr, 2021
  • 235 locations
Combined Breast MRI and Biomarker Strategies in Identifying High-risk Breast Cancer Patients

This clinical trial studies normal breast tissue changes combined with breast magnetic resonance imaging (MRI) that may suggest the beginnings of cancer development. Using breast tissue markers in combination with breast imaging such as MRI may help to more accurately assess a woman's risk of developing breast cancer.

cancer
  • 325 views
  • 18 Jul, 2021
  • 5 locations
A Study to Evaluate the Efficacy and Safety of Nanosomal Docetaxel Lipid Suspension in Triple Negative Breast Cancer Patients

The Nanosomal Docetaxel Lipid Suspension (NDLS) consists of uniformly sized micro particles of docetaxel suspended in a lipid based formulation. The advantage of such a Lipid Based formulation of Docetaxel is an improvement of the safety profile by eliminating excipients, polysorbate 80 and ethanol which are present in conventional Docetaxel …

chemotherapy regimen
breast cancer
serum pregnancy test
measurable disease
docetaxel
  • 56 views
  • 24 Jan, 2021
  • 4 locations
Safety of a Quadrivalent Meningococcal Conjugate Vaccine Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers

The primary objective of this study is to describe the safety profile of MenACYW conjugate vaccine and MENVEO when administered concomitantly with routine pediatric vaccines in healthy infants and toddlers

  • 937 views
  • 26 Jan, 2021
  • 76 locations
Sociocultural & Biobehavioral Influences on Pain Expression and Assessment

Background People can feel different levels of pain. This may depend on social, cultural, and biological factors. These factors can also influence how people respond to each other, and how they judge other people s experiences. Researchers want to learn more about these relationships. Objective To study if social and …

pain assessment
heat
  • 61 views
  • 02 Aug, 2021
  • 1 location
Study of Safety and Efficacy of Novel Immunotherapy Combinations in Patients With Triple Negative Breast Cancer (TNBC).

This is a Phase Ib, open label, dose escalation study of spartalizumab + LAG525 in combination with NIR178, capmatinib, MCS110, or canakinumab, followed by a dose expansion in adult patients with advanced or metastatic TNBC. During the dose-escalation part of each treatment arm, patients will be treated with fixed doses …

measurable disease
estrogen receptor
progesterone
triple negative breast cancer
erbb2
  • 44 views
  • 02 Aug, 2021
  • 13 locations
A Study of Novel Anti-cancer Agents in Patients With Metastatic Triple Negative Breast Cancer

This study is designed to determine the efficacy and safety of durvalumab in combination with novel oncology therapies with or without paclitaxel and durvalumab + paclitaxel for first-line metastatic triple negative breast cancer

breast cancer
triple negative breast cancer
erbb2
trastuzumab
paclitaxel
  • 400 views
  • 02 Aug, 2021
  • 65 locations
Safety and Immunogenicity of a Quadrivalent Meningococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers in the Russian Federation and Mexico

Primary Objective: To describe the antibody titers to the antigens (meningococcal serogroups A, C, Y, and present in MenACYW conjugate vaccine or Menveo measured by serum bactericidal assay using human complement (hSBA), for Groups 1 and 2 when administered concomitantly with routine pediatric vaccines in healthy infants and toddlers in …

  • 7 views
  • 11 Apr, 2021
  • 11 locations