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HIV Clinical Trials

A listing of HIV medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (12) clinical trials

Effects of Glucocorticoids on Cognition in HIV-infected Women

The overall aim of this study is to contribute important foundational knowledge of the utility of targeting neuroinflammation and the hypothalamic-pituitary-adrenal (HPA) axis to improve cognition in HIV and will provide key clinical insights into the mechanisms underlying any cognitive benefit. The investigators are conducting a single-dose study of low ...

Phase N/A

FANMI: Community Cohort Care for HIV-Infected Adolescent Girls in Haiti

The investigators will conduct a randomized controlled trial of Group Care in the GHESKIO Community Center versus Individual Care in the GHESKIO Adolescent Clinic for 160 HIV-infected adolescent girls age 16-19 years in Haiti (80 per arm). Adolescents randomized to Group Care will receive HIV services including integrated clinical and ...

Phase N/A

Point-of-care Viral Load Testing Among HIV-infected Adolescents in Haiti

This study is designed as an individual randomized trial among 150 HIV-infected adolescents aged 10-24 years who have been on ART for >6 months and will be randomized in a 1:1 fashion to one of two arms: 1) the intervention arm (POC) - receiving a POC VL test with adherence ...

Phase N/A

Abnormal Glucose Metabolism in HIV-infected Patients

HIV is a major health problem worldwide especially in low-to middle-income countries including Thailand. Fortunately, a significant reduction in morbidity and mortality has been observed due to the use of combination antiretroviral therapy. As the natural history of the disease is modified, non-communicable diseases are becoming recognized complications of HIV ...

Phase N/A

PrEP Implementation for Mothers in Antenatal Care

Women living in regions with high HIV prevalence are at high risk of HIV acquisition in pregnancy and postpartum because they infrequently use condoms, do not know their partner's HIV status, and have biologic changes or changes in their partner's sexual partnerships that increase susceptibility. Oral pre-exposure antiretroviral prophylaxis (PrEP) ...

Phase

Switch to Genvoya Followed by HCV Therapy With Epclusa in Patients With HIV/HCV Co-Infection on Methadone

This clinical study is a phase IV, prospective, open-label, single arm multi-center study designed to assess the feasibility of the switch from a participant's current antiretroviral therapy regimen to Genvoya, followed shortly thereafter by initiation of Epclusa for treatment of HCV co-infection. A total of 25 participants over the age ...

Phase

Feasibility of SBIRT-PN

The current project will pilot SBIRT with a peer navigator (SBIRT-PN) versus treatment at usual (TAU) to increase substance use treatment engagement among HIV-positive adults aged 50 years and older. The investigators will recruit patients from the Southern HIV and Alcohol Research Consortium (SHARC) HIV primary care clinic network. In ...

Phase N/A

PHAT Life: Peer Versus Adult-Led HIV Prevention for Juvenile Offenders

The main objectives of the proposed study are to compare the effectiveness, cost-effectiveness, and sustainability of Youth Representative-led vs. probation staff-led PHAT Life in a real-world juvenile probation setting. The Specific Aims of this study are: To conduct a methodologically-rigorous 2-arm trial comparing the impact of PHAT Life on 350 ...

Phase N/A

First-in-human Study of 10-1074-LS Alone and in Combination With 3BNC117-LS

The proposed study is a Phase 1, dose escalation cohort study of 10-1074-LS alone or in combination with 3BNC117-LS, administered intravenously and subcutaneously in HIV uninfected and HIV-1 infected individuals. Study participants will be administered a single intravenous infusion of 10-1074-LS at escalating doses of 3, 10 or 30 mg/kg, ...

Phase

Impact of HIV Drug Resistance Testing and Subsequent Change to an Individualized Therapy in Tanzania

HIV/AIDS is one of the main health challenges of our time, with a global burden of disease higher than any other infectious disease. The widespread use of antiretroviral drugs has changed its face from a fatal fate to a chronic disease. However, there are still many differences in the standard ...

Phase N/A