Generalized Anxiety Disorder (GAD) Clinical Trials

A listing of Generalized Anxiety Disorder (GAD) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 221 clinical trials
Assessing Visual Processing in High Anxiety (ALPHA)

High trait anxiety, a stable personality trait, is a risk factor for psychiatric disorders. Individuals with high trait anxiety have difficulty differentiating safety from threat, including visual information like emotional faces. This study aims to characterize visual system function in high trait anxiety. A portion of this study involves an …

Accepts healthy volunteers
  • 24 Mar, 2022
  • 1 location
Immersive Virtual Reality (VR) at the Time of Clinical Evaluation to Improve Psychological Distress and Anxiety in Primary Brain Tumor (PBT) Patients

Background Distress, anxiety, and other psychological disorders may be more common in people with primary brain tumors (PBTs). PBTs can affect their symptoms, quality of life, and their tolerance of cancer treatments. Researchers want to learn if virtual reality (VR) technology can help reduce stress and improve mood. VR uses …

  • 08 Aug, 2022
  • 1 location
Predicting Treatment Response in Patients With OCD

This study consists of a naturalistic follow-up of subjects with Obsessive-Compulsive Disorder (OCD) that have participated in a global study investigating brain signatures of OCD funded by the National Institutes of Mental Health (RO1MH113250), with the following participant sites: the US (Columbia University, PI: Helen Blair Simpson), Brazil (University of …

psychotropic drugs
serotonin reuptake inhibitors
  • 03 Jun, 2022
  • 2 locations
Efficacy of Psilocybin in OCD: a Double-Blind, Placebo-Controlled Study.

This study aims to investigate the effects of oral psilocybin on OCD symptomatology and provide the first evidence of the neural mechanism that may mediate psilocybin's purported therapeutic effects on OCD.

  • 01 Feb, 2022
  • 1 location
Neuroinflammation in Patients With OCD

The goal of this study is to examine whether measurements of inflammation from brain scanning and blood tests can predict how much benefit patients with obsessive-compulsive disorder (OCD) will have from treatment with an anti-inflammatory medication, celecoxib, when adding to ongoing medication-based treatment for OCD.

  • 03 May, 2022
  • 1 location
Assessing Patient Anxiety During Mohs Micrographic Surgery

This study will assess the anxiety that patients are experiencing during a Mohs micrographic surgery. The study will compare the feelings of anxiety experienced by patients returning for Mohs surgery after already undergoing the surgery at least one time to feelings experienced by patients who have never had Mohs surgery …

  • 09 Jul, 2022
  • 1 location
The Role of Serotonin in Compulsive Behavior in Humans: Underlying Brain Mechanisms

The aim of this project is to investigate: The status of the central serotonin (5-hydroxytryptamine, 5-HT) system in compulsive behaviour and how it is affected by sub-chronic escitalopram administration The mechanisms underlying how sub-chronic administration of escitalopram affects the central 5-HT system How changes in cognitive performance, including the balance …

compulsive behavior
  • 24 Jan, 2021
  • 1 location
Theta Burst Stimulation Plus Habit Override Training for Compulsive Behaviors

This project seeks to identify causal neural mechanisms underlying unwanted, repetitive behaviors (compulsions). Using non-invasive brain stimulation coupled with practice in a computer task, we will modulate activity in a target brain region and measure effects on compulsive behaviors and related measures. This work could ultimately lead to the ability …

treatment regimen
brain stimulation
transcranial magnetic stimulation
  • 18 Dec, 2021
  • 1 location
Mindfulness-Based Intervention for Adolescents

The Mindfulteen Study is a 3-year long longitudinal cohort study with a nested randomized controlled trial, integrating neuroimaging, biological and clinical outcomes, and designed to evaluate the impact of a mindfulness-based intervention (MBI) on young adolescents. Young adolescents between 13 and 15 years with no history of current mental health …

  • 02 Feb, 2021
  • 1 location
The Efficacy and Mechanism of DBS in VIC and NAcc for Refractory OCD

This study will evaluate the efficacy and explore the mechanism of deep brain stimulation (DBS) in the ventral internal capsule (VIC) and nucleus accumbens (NAc) for refractory obsessive-compulsive disorder (OCD).

behavior therapy
treatment regimen
cognitive therapy
  • 23 Feb, 2022
  • 1 location