Generalized Anxiety Disorder (GAD) Clinical Trials

A listing of Generalized Anxiety Disorder (GAD) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
I am looking for
added new label for I am looking for
Advanced Filters
Found 204 clinical trials
European Study of Quality of Life in Resistant OCD Patients Treated by STN DBS (EQOLOC)

Obsessive-Compulsive Disorder (OCD) is among the most disabling psychiatric disorders as more than 40% of patients are resistant to the standard pharmacological and psychotherapy approaches and about 10% show severe disability and require institutionalization. These resistant patients may benefit from new surgical therapeutic approaches such as Deep Brain Stimulation (DBS) …

brain stimulation
exposure therapy
psychiatric disorder
  • 20 Apr, 2022
  • 5 locations
StoryTelling Medicine Application Using a Virtual Reality Intervention (STM)

Preoperative anxiety (PA) affects up to 5 million children in North America each year and is associated with adverse medical, psychological, and behavioral effects. Children who are highly anxious often require more medications during surgical procedures and take longer to recover. While many attempts have been made to reduce PA …

anxiety reduction
elective surgery
  • 27 Feb, 2022
  • 1 location
Parental Guidance for Failure to Launch. (SPACE-FTL)

In the proposed study the outcome of administering parental guidance, based on the Supportive Parenting for Anxious Childhood Emotions (SPACE) program, to parents of highly dependent adult children will be explored. The proposed study's primary purpose is to assess the outcome of parental guidance. In addition, the study will also …

Accepts healthy volunteers
  • 17 Mar, 2022
  • 1 location
Brain Network Changes Accompanying and Predicting Responses to Pharmacotherapy in OCD

The proposed randomized, double-blind research study will use functional magnetic resonance neuroimaging using state-of-the-art HCP acquisition protocols and analytic pipelines, to identify predictors and correlates of response to an accepted first-line pharmacological treatment for obsessive-compulsive disorder.

Accepts healthy volunteers
body dysmorphic disorder
  • 13 Jun, 2022
  • 1 location
Short and Intensive Treatment of Children and Adolescents With Obsessive-Compulsive Disorder

Obsessive-compulsive disorders are very damaging illnesses; they can already appear in childhood and adolescence and become extremely chronic. With an average prevalence from 1-3%, they are among the most common psychiatric disorders in children and adolescents. 40% of diagnosed children and young adults display persistent and increasingly chronic symptoms and …

behavior therapy
  • 23 Apr, 2022
  • 1 location
A Clinical Trial of a Hemp-Derived Cannabidiol Product for Anxiety

This open-label to double-blind study evaluates the impact of cannabidiol (CBD) on anxiety in adults. Participants will use a custom-formulated sublingual (under-the-tongue) solution of whole plant, hemp-derived CBD twice daily for six weeks in addition to their normal treatment regimen. Participants' clinical state will be assessed weekly during the treatment …

  • 15 Apr, 2021
  • 1 location
Assessing Visual Processing in High Anxiety (ALPHA)

High trait anxiety, a stable personality trait, is a risk factor for psychiatric disorders. Individuals with high trait anxiety have difficulty differentiating safety from threat, including visual information like emotional faces. This study aims to characterize visual system function in high trait anxiety. A portion of this study involves an …

Accepts healthy volunteers
  • 24 Mar, 2022
  • 1 location
Predicting Treatment Response in Patients With OCD

This study consists of a naturalistic follow-up of subjects with Obsessive-Compulsive Disorder (OCD) that have participated in a global study investigating brain signatures of OCD funded by the National Institutes of Mental Health (RO1MH113250), with the following participant sites: the US (Columbia University, PI: Helen Blair Simpson), Brazil (University of …

serotonin reuptake inhibitors
psychotropic drugs
  • 03 Jun, 2022
  • 2 locations
Efficacy of Psilocybin in OCD: a Double-Blind, Placebo-Controlled Study.

This study aims to investigate the effects of oral psilocybin on OCD symptomatology and provide the first evidence of the neural mechanism that may mediate psilocybin's purported therapeutic effects on OCD.

  • 01 Feb, 2022
  • 1 location
Pharmacogenetically-guided Escitalopram Treatment for Pediatric Anxiety: Aiming to Improve Safety and Efficacy (PrEcISE) (PrEcISE)

This double-blind, 12-week study will consist include132 anxious youth who are randomized (1:1) to standard or pharmacogenetically-guided escitalopram dosing. Block randomization (1:1) will be stratified by sex and metabolizer status.

Accepts healthy volunteers
  • 22 Mar, 2022
  • 1 location