Islet Ce417ll Cancer Clinical Trials

A listing of Islet Ce417ll Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 53 clinical trials
Comparing Two Methods to Follow Patients With Pancreatic Cysts

The purpose of this study is to compare the two approaches for monitoring pancreatic cysts. The study doctors want to compare more frequent monitoring vs less frequent monitoring in order to learn which monitoring method leads to better outcome for patients with pancreatic cysts.

endoscopic ultrasound
adenocarcinoma
pancreatitis
pancreatic adenocarcinoma
pancreatic resection
  • 67 views
  • 04 Oct, 2022
  • 193 locations
A Phase 2, Open-Label, Randomized Study to Assess the Efficacy and Safety of Zolbetuximab (IMAB362) in Combination With Nab-Paclitaxel and Gemcitabine (Nab-P + GEM) as First Line Treatment in Subjects With Claudin 18.2 (CLDN18.2) Positive, Metastatic Pancreatic Adenocarcinoma

The purpose of this study is to confirm the recommended phase 2 dose (RP2D) of zolbetuximab in combination with Nab-P + GEM, determine overall survival and assess the safety and tolerability of the combination treatment. This study will also evaluate tumor markers and pharmacokinetics (PK) of zolbetuximab, Nab-P and GEM, …

tumor cells
gemcitabine
liver metastasis
measurable disease
international normalized ratio
  • 251 views
  • 21 Oct, 2022
  • 89 locations
A First-in-human Phase Ia/b, Open Label, Multicentre, Dose Escalation Study of BI 905711 in Patients With Advanced Gastrointestinal Cancers

Phase Ia - Explore safety and establish the maximum tolerated dose (MTD)/recommended dose levels for phase Ib expansion phase of BI 905711 based on the frequency of patients experiencing dose limiting toxicities (DLTs) during the MTD evaluation period. The MTD evaluation period is defined as the first two treatment cycles …

cancer
adenocarcinoma
esophageal adenocarcinoma
liver metastasis
gastrointestinal cancer
  • 76 views
  • 20 Oct, 2022
  • 14 locations
The Cancer of the Pancreas Screening-5 CAPS5)Study (CAPS5)

Johns Hopkins clinical research office quality assurance group will monitor and audit this study at Johns Hopkins. The Sub Investigator at each site will be responsible for internal monitoring at their site.

cancer
synthetic secretin
pancreatitis
fammm
BRCA1
  • 185 views
  • 04 Oct, 2022
  • 8 locations
A Phase I, Open-label, Dose Escalation Study of Oral LGK974 in Patients With Malignancies Dependent on Wnt Ligands

The primary purpose of this study is to find the recommended dose of LGK974 as a single agent and in combination with PDR001 that can be safely given to adult patients with selected solid malignancies that have progressed despite standard therapy or for which no effective standard therapy exists

cancer
adenocarcinoma
melanoma skin
metastasis
immunomodulators
  • 1231 views
  • 29 Oct, 2022
  • 15 locations
A Phase 1/2, Open-label, Multi-center Study of the Safety and Efficacy of KY1044 as Single Agent and in Combination With Anti-PD-L1 (Atezolizumab) in Adult Patients With Selected Advanced Malignancies

A Phase 1/2, open label, multi-center study to evaluate the safety, efficacy and tolerability of KY1044 as single agent and in combination with anti-PD-L1 (atezolizumab) in adult patients with selected advanced malignancies, who are ineligible for or there are no available therapies known to confer a clinical benefit for their …

lung carcinoma
cancer
measurable disease
triple negative breast cancer
squamous cell carcinoma
  • 101 views
  • 18 Oct, 2022
  • 10 locations
An Adaptive Approach to Neoadjuvant Therapy to Maximize Resection Rates for Pancreatic Adenocarcinoma: A Phase II Trial

The purpose of this study is to determine if neoadjuvant therapy to increases resection rate for pancreatic adenocarcinoma.

  • 0 views
  • 15 Oct, 2022
  • 2 locations
Electron Beam Intraoperative Radiation Therapy Following Chemoradiation in Patients With Pancreatic Cancer With Vascular Involvement (PACER)

This research study is studying an intervention as a possible treatment for pancreatic cancer.

folfirinox
gemcitabine
stereotactic body radiation therapy
leucovorin
fluorouracil
  • 2 views
  • 07 Oct, 2022
  • 5 locations
Phase II Study to Evaluate Modified Folfirinox and Stereotactic Body Radiation Therapy in Non-metastatic Unresectable Pancreatic Adenocarcinoma

The purpose of this study is to evaluate the efficacy of modified FOLFIRINOX followed by stereotactic body radiotherapy (SBRT) in patients with borderline resectable pancreatic cancer (BRPC) and locally advanced pancreatic cancer (LAPC). The primary hypothesis will be to determine if modified FOLFIRINOX followed by SBRT improves progression free survival …

folfirinox
adenocarcinoma
stereotactic body radiation therapy
resectable pancreatic cancer
gemcitabine
  • 3 views
  • 16 Oct, 2022
  • 1 location
Identification of Personalized Treatment Utilizing Master Regulator Gene Targets in Pancreatic Cancer (HIPPOCRATES)

The overall objective of this project is to determinate the feasibility of administering personalized therapy to subjects with advanced pancreatic cancer utilizing the novel OncoTreat platform. The primary objective of this study is to assess the feasibility of implementing the OncoTreat framework in patients with newly diagnosed, untreated metastatic pancreatic …

pancreatic ductal adenocarcinoma
adenocarcinoma
pancreatic adenocarcinoma
breast ductal carcinoma
cancer chemotherapy
  • 0 views
  • 24 Oct, 2022
  • 1 location