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Neoplasms Clinical Trials

A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (101) clinical trials

Norwegian Pancreatic Cancer Trial (NorPACT) - 1

Pancreatic cancer is the fourth leading cause of cancer-related deaths in Europe and the United States. Surgical resection remains the only potentially curative treatment. However, the median survival of patients undergoing pancreatic resection alone is 16-23 months. The administration of adjuvant chemotherapy leads to an improvement in overall survival. Thus, ...

Phase

Perioperative Systemic Therapy and Surgery Versus Surgery Alone for Resectable Colorectal Peritoneal Metastases.

Rationale: Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS + HIPEC) and systemic therapy are increasingly used for the treatment of peritoneal metastases of colorectal cancer (PMCRC). Subsequently, combined treatment strategies have been introduced, with the use of perioperative systemic therapy, either neoadjuvant or adjuvant, as adjunct to CRS + HIPEC. ...

Phase

Netupitant and Palonosetron (AKYNZEO) for Chronic Nausea and Vomiting in Cancer Patients

Study Drug Administration: If you are still eligible to take part in this study, you will be randomly assigned (as in the roll of dice) to 1 of 2 groups. This is done because no one knows if one study group is better, the same, or worse than the other ...

Phase

Trial of Preoperative Therapy for Gastric and Esophagogastric Junction Adenocarcinoma

Gastric cancer remains a significant global public health problem. Although in developed countries its incidence has dramatically decreased, on a worldwide scale it is still a leading cause of cancer-related deaths. Surgery is the only potentially curative treatment for gastric cancer. Although the survival rates for patients with early stage ...

Phase

The Efficacy and Safety of Preoperative Misoprostol in Blood-loss Reduction During Myomectomy.

Uterine fibroids are the commonest benign gynecological tumors in pre-menopausal women affecting over 80% of African women by age of 50. Myomas are clinically apparent in approximately 12 to 25% of reproductive age women and noted coincidentally on pathological examination in approximately 80% of surgically excised uteri. Fibroids; clinically apparent ...

Phase

Letrozole Plus Low-Dose Metronomic Capecitabine Versus EC-T (Epirubicin/Cyclophosphamide Followed by Docetaxel) as Neoadjuvant Therapy for ER+/HER2-negative Breast Cancer

Patients with ER+/HER2 breast cancer (presumably the luminal A subtype) could potentially avoid the standard chemotherapy use. Letrozole Plus Low-Dose Metronomic Capecitabine may offer similar efficacy and less toxicity to standard chemotherapy in ER+/HER2 breast cancer patients.

Phase

Standard PET/CT vs. Digital PET/CT

There will be a single injection of the PET radiopharmaceutical followed by a standard PET/CT scan and immediately after by the digital PET/CT scan, or vice versa. The investigators wish to determine if image quality is equivalent with the digital PET/CT scanner.

Phase

Value of LNG-IUS as Fertility-preserving Treatment of EAH and EC

Primary end points: This clinical trial is aimed to analyze the effectiveness of Levonorgestrel-Releasing Intrauterine System (LNG-IUS, Mirena) in the fertility-sparing treatment of atypical endometrial hyperplasia and early endometrial carcinoma, including pathology response and pregnancy outcome. Second end points: To analyze the appearances of side-effects.

Phase

Magnetic Resonance Tumour Regression Grade as Biomarker for Stratified Management of Rectal Cancer Patients

Approximately half of patients diagnosed with rectal cancer are offered chemotherapy and radiotherapy treatment (CRT) before surgery. There is great variability in how each tumour responds to CRT. Approximately 30% of tumours completely respond and no cancer cells can be found in the cancer specimen removed at surgery. Other tumours ...

Phase

Maekmoondong-tang on Post-operative Cough in Patients With Lung Cancer

The aim of the present study is to evaluate the efficacy and safety of Maekmoondong-tang on post-operative cough in patients with lung cancer. A randomized, double-blind, placebo-controlled trial will be conducted.

Phase