Neoplasms Clinical Trials

A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 1629 clinical trials
featured
Phase 2 Trial of MRTX849 in Combination with Pembrolizumab in Patients with Advanced Non-Small Cell Lung Cancer with KRAS G12C Mutation (KRYSTAL-7)

This Phase 2 study evaluates the clinical activity and safety of MRTX849 in combination with pembrolizumab in cohorts of patients with advanced NSCLC with KRAS G12C mutation and any PD-L1 TPS.

pembrolizumab
KRAS
  • 0 views
  • 23 Jun, 2021
  • 35 locations
featured
A Randomized Phase 3 Study of MRTX849 in Combination with Cetuximab Versus Chemotherapy in Patients with Advanced Colorectal Cancer with KRAS G12C Mutation with Disease Progression On or After Standard First-Line Therapy (KRYSTAL-10)

Study 849-010 is an open-label, randomized Phase 3 clinical trial comparing the efficacy of MRTX849 administered in combination with cetuximab versus chemotherapy in the second-line treatment setting in patients with CRC with KRAS G12C mutation.

  • 0 views
  • 16 Jun, 2021
  • 18 locations
featured
Wake Forest WF-1801 A Single Arm, Pilot Study of Ramipril for Preventing Radiation - Induced Cognitive Decline in Glioblastoma (GBM) Patients Receiving Brain Radiotherapy

People who were just diagnosed with glioblastoma and have yet to get treatment may be eligible.  This trial is investigating whether a common blood pressure drug is helpful to prevent or diminish side effects of radiation when it is combined with the standard treatment for glioblastoma.  

brain tumor
cancer
  • 2 views
  • 24 Jun, 2021
  • 1 location
featured
Alliance A071701 Genomically-Guided Treatment Trial in Brain Metastases

People with recurrent or progressive brain metastases may be eligible for this trial.  All tumors will be submitted to the Alliance biorepository for tracking and processing

brain tumors
solid tumor
brain metastases
brain tumor
solid tumors
  • 40 views
  • 24 Jun, 2021
  • 1 location
featured
OT-15-001 (STELLAR) A Phase 3, Randomized, Open-Label Study To Evaluate the Efficacy and Safety of Eflornithine with Lomustine Compared to Lomustine Alone in Patients with Anaplastic Astrocytoma That Progress/Recur After irradiation and Adjuvant Temozolomide Chemotherapy

People who were previously diagnosed with an anaplastic astrocytoma (WHO grade III astrocytoma) and now have evidence that their tumor has returned or has tarted to grow again without concern

brain tumor
brain tumors
astrocytoma
  • 10 views
  • 24 Jun, 2021
  • 1 location
featured
CG01-GBM Standard Chemotherapy versus Chemotherapy Chosen by Cancer Stem Cell Chemosensitivity Testing in the Management of Patients with Recurrent Glioblastoma Multiforme (GBM)

People who were previously diagnosed with glioblastoma (Grade IV) or Grade III glioma, and now have evidence that their tumor has come back or has started to grow again, and who would otherwise

brain tumor
glioblastoma
  • 117 views
  • 24 Jun, 2021
  • 1 location
featured
N0577 (CODEL) Phase III Intergroup Study of Radiotherapy with Concomitant and Adjuvant Temozolomide versus Radiotherapy with Adjuvant PCV Chemotherapy in Patients with 1p/19q co-deleted Anaplastic Glioma or Low Grade Glioma

People who are diagnosed with an oligodendroglioma and who haven't yet undergone treatment may be eligible.  This study is comparing two standard regimens, radiation followed by PCV (Procarbazine, CCNU, and Vincristine) or radiation with temozolomide during and after radiation, to see which is better.  

oligodendroglioma
brain tumors
vincristine
brain tumor
temozolomide
  • 10 views
  • 24 Jun, 2021
  • 1 location
featured
GBM AGILE An International, Seamless Phase II/III Responsive Adaptive Randomization Platform Trial Designed To Evaluate Multiple Regimens in Newly Diagnosed and Recurrent GBM

People with either a new diagnosis of glioblastoma or with evidence that their tumor has returned or started to grow again may be eligible.  This trial is studying multiple

brain tumor
glioblastoma multiforme
  • 0 views
  • 24 Jun, 2021
  • 1 location
AZD4573 in Novel Combinations With Anti-cancer Agents in Patients With Advanced Blood Cancer.

, in novel combinations with anti-cancer agents, to participants with relapsed/refractory haematological malignancies.

  • 0 views
  • 21 Jun, 2021
  • 25 locations
Osimertinib Alone or With Chemotherapy for EGFR-Mutant Lung Cancers

This study will compare the effectiveness of osimertinib alone with the combination of osimertinib and chemotherapy (carboplatin and pemetrexed) in people with metastatic lung cancer that has a

metastasis
EGFR
carboplatin
cancer
liver metastasis
  • 0 views
  • 23 Jun, 2021
  • 11 locations