Diabetes (Pediatric) Clinical Trials

A listing of Diabetes (Pediatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 56 clinical trials
Study of Safety and Efficacy of CFZ533 in Type 1 Diabetes Pediatric and Young Adult Subjects

The study is a Phase 2, multicounty, multicenter, non-confirmatory, investigator- and subject masked, randomized, placebo-controlled study to evaluate the safety, tolerability, pharmacokinetics, and efficacy of CFZ533 on preservation of residual pancreatic -cell function in new onset T1DM in pediatric and young adult subjects.

tolerance test
glutamic acid
diabetes
immune tolerance
c-peptide
  • 10 views
  • 23 Jun, 2021
  • 11 locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

cardiovascular disease
hemoglobin a1c
body mass index
  • 593 views
  • 24 Jun, 2021
  • 881 locations
A Study of Tirzepatide (LY3298176) Versus Insulin Lispro (U100) in Participants With Type 2 Diabetes Inadequately Controlled on Insulin Glargine (U100) With or Without Metformin

The purpose of this study is to compare the safety and efficacy of the study drug tirzepatide to insulin lispro (U100) three times a day in participants with type 2 diabetes that are already on insulin glargine (U100), with or without metformin.

hemoglobin a1c
type 2 diabetes mellitus
metformin
insulin
  • 0 views
  • 23 Jun, 2021
  • 161 locations
Ertugliflozin Type 2 Diabetes Mellitus (T2DM) Pediatric Study (MK-8835/PF-04971729) (MK-8835-059)

This study will evaluate the safety and efficacy of ertugliflozin (MK-8835) in pediatric participants with T2DM on metformin with/without insulin. The primary hypothesis of the study is that the addition of ertugliflozin reduces hemoglobin A1C (HbA1C) more than the addition of placebo after 24 weeks of treatment.

fasting
metformin
hemoglobin a1c
c-peptide
type 2 diabetes mellitus
  • 271 views
  • 23 Jun, 2021
  • 106 locations
A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes Who Have Obesity or Are Overweight

This is a study of tirzepatide in participants with type 2 diabetes who have obesity or are overweight. The main purpose is to learn more about how tirzepatide affects body weight. The study will last 79 weeks (22 visits).

glucagon-like peptide-1
hemoglobin a1c
glucagon
diabetes
  • 0 views
  • 23 Jun, 2021
  • 90 locations
New Heart Imaging Techniques to Evaluate Possible Heart Disease

Background Imaging tests, such as magnetic resonance imaging (MRI), can provide information about heart and blood vessels. The tests let doctors can see the amount of blood vessel narrowing and vessel wall thickness. This information may help diagnose and treat heart disease and other conditions that lead to heart attacks. …

hypertension
MRI
hyperlipidemia
metabolic syndrome
diabetes mellitus
  • 105 views
  • 22 Jun, 2021
  • 1 location
A Study of Two Doses of Dulaglutide (LY2189265) in Japanese Patients With Type 2 Diabetes

The purpose of this study is to evaluate the efficacy and safety of 2 doses of dulaglutide in Japanese participants with type 2 diabetes. The study duration is approximately 58 weeks.

alpha-glucosidase inhibitor
sulfonylurea
hemoglobin a1c
body mass index
  • 0 views
  • 16 Jun, 2021
  • 40 locations
Visualizing Beta Cells in Patients With a History of Gestational Diabetes

In order to evaluate the difference in beta cell mass in women with and without a history of gestational diabetes mellitus (GDM), investigators aim to compare quantitative PET imaging of the pancreas between these groups. Investigators propose to measure uptake of 68Ga-NODAGA-exendin-4 in the pancreatic beta cells of these women …

tolerance test
exenatide
diabetes
oral glucose tolerance test
glucose tolerance test
  • 1 views
  • 24 Jun, 2021
  • 1 location
Identifying Therapeutic Targets of Accelerated Sarcopenia

The proposed research is designed to identify the mechanisms that can accelerate loss of muscle size, strength and physical function in type 2 diabetes and with hospitalization in older persons. About of older Americans have type 2 diabetes, and about of the hospitalizations in the USA involve persons older than …

sarcopenia
diabetes
diabetes mellitus
mini-mental state examination
mental state examination
  • 152 views
  • 23 Jun, 2021
  • 1 location
An Open-Label Pilot Intervention Trial to Prevent Diabetes in Prediabetic Adult Survivors of Childhood Cancer

This is a first-in survivor, single-arm pilot study with the goal of establishing evidence of feasibility and safety of a combined pharmacologic (metformin) and lifestyle intervention (using an existing digital platform) to prevent diabetes in prediabetic adult survivors of childhood cancer. Primary Objective The primary aim of this proposal is …

insulin resistance
fasting
metformin
hemoglobin a1c
plasma glucose
  • 0 views
  • 19 Jun, 2021
  • 1 location