Diabetes (Pediatric) Clinical Trials

A listing of Diabetes (Pediatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 69 clinical trials
A Study to Evaluate THR-149 Treatment for Diabetic Macular Oedema

This study is conducted to select the THR-149 dose level (Part A of the study) and to assess the efficacy and safety of the selected dose level compared to aflibercept (Part B of the study).

vegf
macular edema
bevacizumab
sd-oct
aflibercept
  • 20 views
  • 18 Sep, 2021
  • 39 locations
Aspirin Twice a Day in Patients With Diabetes and Acute Coronary Syndrome

To compare treatment with Aspirin Protect twice a day (100 mg in the morning and 100 mg in the evening) versus Aspirin Protect 100 mg once per day on a composite end-point of ischemic events in diabetic patients, or in patients with a known risk factor for non-optimal aspirin response …

cardiac troponin
acute coronary syndrome
aspirin
stenosis
electrocardiogram
  • 0 views
  • 19 Sep, 2021
  • 1 location
Prevalence of Carbohydrate Intolerance in Lean and Overweight/Obese Children

The purpose of this study is to determine the prevalence of impaired glucose (carbohydrate) tolerance in lean children with a family history of diabetes and in overweight/obese children with or without a family history of diabetes mellitus.

oral glucose tolerance test
glucose tolerance test
type 2 diabetes mellitus
diabetes
  • 0 views
  • 12 Sep, 2021
  • 1 location
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

cardiovascular disease
body mass index
hemoglobin a1c
  • 597 views
  • 12 Sep, 2021
  • 896 locations
Ertugliflozin Type 2 Diabetes Mellitus (T2DM) Pediatric Study (MK-8835/PF-04971729) (MK-8835-059)

This study will evaluate the safety and efficacy of ertugliflozin (MK-8835) in pediatric participants with T2DM on metformin with/without insulin. The primary hypothesis of the study is that the addition of ertugliflozin reduces hemoglobin A1C (HbA1C) more than the addition of placebo after 24 weeks of treatment.

metformin
c-peptide
hemoglobin a1c
type 2 diabetes mellitus
insulin
  • 277 views
  • 19 Sep, 2021
  • 106 locations
A Study of Tirzepatide (LY3298176) Versus Insulin Lispro (U100) in Participants With Type 2 Diabetes Inadequately Controlled on Insulin Glargine (U100) With or Without Metformin

The purpose of this study is to compare the safety and efficacy of the study drug tirzepatide to insulin lispro (U100) three times a day in participants with type 2 diabetes that are already on insulin glargine (U100), with or without metformin.

insulin
metformin
type 2 diabetes mellitus
hemoglobin a1c
  • 0 views
  • 12 Sep, 2021
  • 169 locations
Evaluation of the Efficacy and Safety of Duodenal Mucosal Resurfacing Using the Revita System in Subjects With Type 2 Diabetes on Insulin Therapy

The Revita system is being investigated to assess the efficacy of DMR versus Sham on improvement in Glycemic, Hepatic and Cardiovascular endpoints for patients with Type 2 Diabetes who are inadequately controlled with insulin therapy. The purpose of this study is to demonstrate the efficacy and safety of the Fractyl …

glycosylated hemoglobin
metformin
hemoglobin a1c
insulin
body mass index
  • 0 views
  • 12 Sep, 2021
  • 37 locations
Medical Optimization of Management of Type 2 Diabetes Complicating Pregnancy (MOMPOD)

Purpose: The objective of this proposal is to study the safety and efficacy of metformin added to insulin for treatment of type 2 diabetes mellitus (T2DM) among pregnant women. Participants: 950 pregnant women with type 2 diabetes complicating pregnancy from 10 U.S. clinical centers Procedures (methods): Pregnant women with T2DM …

insulin
hypoglycemic agents
prenatal
metformin
diabetes
  • 71 views
  • 19 Sep, 2021
  • 10 locations
Multi-center Trial in Adult and Pediatric Patients With Type 1 Diabetes Using Hybrid Closed Loop System and Control at Home

The purpose of this study is to evaluate the safety and effectiveness of the Hybrid Closed Loop system (HCL) in adult and pediatric patients with type 1 diabetes in the home setting. A diverse population of patients with type 1 diabetes will be studied. The study population will have a …

celiac disease
novolog
hemoglobin a1c
insulin
diabetic ketoacidosis
  • 0 views
  • 17 Sep, 2021
  • 48 locations
TRIgyceride And Glucose Control With Epeleuton in Metabolic Syndrome Patients

To assess the efficacy and safety of orally administered Epeleuton capsules versus placebo, in the treatment of adult patients with hypertriglyceridemia and type 2 diabetes

diabetes
hemoglobin a1c
type 2 diabetes mellitus
fasting
metabolic syndrome
  • 0 views
  • 17 Sep, 2021
  • 27 locations