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Common Cold Clinical Trials

A listing of Common Cold medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (24) clinical trials

Population Pharmacokinetics and Pharmacodynamics of Beta-lactams of Interest in Adult Patients From Intensive Care Units

Background, Literature Survey and Justification of The Study 1.1. Introduction -lactams efficacy depends primarily from the time interval during which the plasma concentration remains above the minimal inhibitory concentration (MIC) of the antibiotic against the target organism(s) (Craig, 1998). It is generally accepted that the free concentration of the antibiotic ...

Phase N/A

Exploratory Study of Intrapulmonary Microdosing of Gram-negative Optical Imaging Detection Probe

The primary objective of this study is to deliver a BAC TWO microdose to 3 ventilated controls and 9 patients to assess the imaging parameters of BAC TWO over human autofluorescence and to assess if gram-negative bacteria can be detected in vivo in situ within the distal lung. The primary ...

Phase N/A

A Multifaceted Intervention to Improve Prescribing for Acute Respiratory Infection for Adults and Children in Emergency Department and Urgent Care Settings

In this proposed acute care project, the investigators will compare a package consisting of education for providers using existing materials from CDC's GetSmart campaign adapted for the acute care setting led by a physician champion at each site (the adapted intervention), to a more intensive intervention that incorporates adapted GetSmart ...

Phase N/A

Targeted AntiBiotics for Chronic Obstructive Pulmonary Disease

P. aeruginosa represents a potentially significant cause of acute exacerbation of COPD (AECOPD) and is possibly associated with significant morbidity and mortality. Despite this, the role of P. aeruginosa in the course of COPD is less well characterized, and evidence based guidelines for management and treatment of the bacteria are ...

Phase

Safety Tolerability DDI Short Course Treatment of LTBI Infection With High-dose Rifapentine Isoniazid in HIV+ Patients

Single-arm, single-center, Phase I/II clinical trial, in two Groups. Individuals with HIV infection taking EFV and two nucleoside reverse transcriptase inhibitors (NRTI) who have undetectable HIV viral load and an indication for treatment of LTBI, will be switched to DTG with tenofovir/emtricitabine for at least two months and will receive ...

Phase

Sequential Cadaveric Lung and Bone Marrow Transplant for Immune Deficiency Diseases

This is an original IND for an investigator initiated phase I/II study. The primary purpose of the study is to evaluate the safety and efficacy of performing bilateral orthotopic lung transplantation (BOLT) followed by cadaveric, partially HLA-matched CD3+/CD19+-depleted hematopoietic stem cell transplantation (HSCT) from the same donor for patients with ...

Phase

Efficacy Safety and Immunogenicity of a Plant-Derived Quadrivalent Virus-Like Particles Influenza Vaccine in Adults

This randomized, observer-blind, placebo-controlled multicenter, Phase 3 study will be conducted at multiple sites. The composition of the Quadrivalent VLP Influenza Vaccine to be used in this study includes a mix of recombinant H1, H3, and two B hemagglutinin proteins expressed as VLPs for the 2017-2018 influenza virus strains. Approximately ...

Phase

Effect of OC459 on the Response to Rhinovirus Challenge in Asthma

Asthma is the most common chronic respiratory disease, and in many countries prevalence is rising. The major morbidity, mortality and health care costs related to asthma are a result of periods of acutely increased symptomatology called 'exacerbations'. Most exacerbations are caused by rhinovirus, the virus associated with the common cold. ...

Phase

Fluid Restriction Keeps Children Dry

Rationale: Fluid overload is a common complication in children who are admitted to the pediatric intensive care for mechanical ventilation. Acute lung infection is a frequent cause for admission to the PICU and forms an uniform group with a single organ failure. In these critically ill children, fluid overload is ...

Phase

Using a Cold Atmospheric Plasma Device to Treat Skin Disorders

This study examines the efficacy of a non-thermal, atmospheric plasma device in the treatment of a number of different skin disorders

Phase N/A