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Cancer/Tumors Clinical Trials

A listing of Cancer/Tumors medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (1982) clinical trials

Pharmacokinetics of Dactinomycin in Young Patients With Cancer

OBJECTIVES: - Determine the pharmacokinetics (PKs) of dactinomycin in pediatric patients with cancer. - Determine the degree of interpatient variation in the PKs of this drug. - Determine the influence of characteristics such as age, tumor type, and concurrent therapy on drug PKs in these patients. - Correlate drug PKs ...

Phase N/A

Effect of Bevacizumab and VEGF on Platelet Clustering in Patients Who Are Receiving Bevacizumab for Cancer

OBJECTIVES: - To determine the influence of bevacizumab on platelet aggregation in patients receiving bevacizumab for cancer. - To determine the influence of VEGF on platelet aggregation. - To determine the influence of VEGF or bevacizumab on cyclooxygenesis. - To determine if the sequence of medication plays a role in ...

Phase N/A

Blood Sample Collection and Health Information Collection From Patients With Invasive Breast Cancer and Their Brothers and Sisters

OBJECTIVES: - Collect blood samples and medical and background information from patients with invasive breast cancer and their affected or unaffected siblings. OUTLINE: Patients and their siblings undergo blood collection. They also complete medical and background questionnaires. Patients and their siblings are followed annually for 5 years. PROJECTED ACCRUAL: A ...

Phase N/A

Biomarkers in Predicting Response to Tamoxifen and Letrozole in Postmenopausal Women With Primary Breast Cancer Treated on Clinical Trial CAN-NCIC-MA17

OBJECTIVES: - Assess the prognostic utility of the MGH 2-gene and the GHI 21-gene expression signatures in postmenopausal women with primary breast cancer treated with tamoxifen followed by either placebo or letrozole on clinical trial CAN-NCIC-MA17. - Assess the ability of the MGH 2-gene and the GHI 21-gene expression signatures ...

Phase N/A

Submission of Stem Cell Transplant Data to CIBMTR and NMDP

Background: - In 2005, the United States Congress legislated that outcome data would be collected on all patients who have been recipients of a stem cell therapeutics product (including bone marrow, cord blood, or other such product) from a donor. The Health Services and Resources Administration (HRSA) awarded the contract ...

Phase N/A

Liverpool Lung Project: Risk Factors and Genetic Markers in Healthy Participants and Patients With Lung Cancer

OBJECTIVES: - To prepare a molecular genetic and epidemiological risk assessment model based on the analysis of environmental exposures and genetic predisposition, which will provide an algorithm to measure an individual's risk for developing lung cancer. - To develop an archive of specimens relating to at-risk individuals and those with ...

Phase N/A

Characterization of Receptors in Non-functioning Pituitary Macroadenomas

The pituitary gland in the brain is the master hormonal gland and is surrounded by important nerves and blood vessels. The pituitary gland can develop various types of tumors, some which do not produce any hormones and are called non-functioning pituitary adenomas. These non-functioning tumors can grow and can cause ...


Studying DNA in Patients With Stage I Stage II Stage III or Stage IV Ovarian Epithelial Cancer

OBJECTIVES: - To determine if DNA methylation patterns and expression of differentially methylated genes taken before chemotherapy can predict patient outcome with regard to progression-free survival. - To evaluate whether DNA methylation can predict response assessed by RECIST criteria and CA 125 response. - To evaluate the specificity and sensitivity ...

Phase N/A

Collaborative Registry of Patients With Thyroid Cancer and/or Thyroid Tumors

OBJECTIVES: Primary - To develop a web-based Thyroid Tumor and Cancer Collaborative Registry as a repository for socio-demographic, environmental, clinical history, family history, and biospecimen data collected at the University of Nebraska Medical Center/Nebraska Medical Center (UNMC/NMC) for study participants with a personal history of thyroid cancer and/or thyroid nodules. ...

Phase N/A