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Cancer/Tumors Clinical Trials

A listing of Cancer/Tumors medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (408) clinical trials

The purpose of this research study is to compare any good and bad effects of using the study drug, crizotinib (also known as XALKORI®), after completion of surgery and, in some cases, after chemotherapy and/or radiation therapy for ALK-positive non-small cell lung cancer. The addition of crizotinib may help prevent ...

Phase

LifeSeal™ Kit, surgical sealant designed for staple-line reinforcement that is applied over the anastomotic line to prevent bowel content leakage until full physiological function is restored. RATIONALE : Postoperative anastomotic leakage is one of the most devastating and feared complications in colorectal surgery. The risk of postoperative anastomotic leakage varies ...

Phase

This study will enable patients receiving sorafenib (Nexavar) in the completed Bayer/Onyx sponsored clinical trials to continue treatment. During the entire course of the study, numerous patients will be treated with sorafenib. Involvement in this study will be depending on whether the patient benefits from the treatment or not, based ...

Phase

The purpose of this study is to evaluate the efficacy and safety of pemigatinib versus gemcitabine plus cisplatin chemotherapy in first-line treatment of participants with unresectable or metastatic cholangiocarcinoma with FGFR2 rearrangement.  

Phase

The SPOTLIGHT study is a new clinical study for adults with newly diagnosed, advanced or metastatic stomach or gastroesophageal junction (GEJ) cancer who: Have not had any chemotherapy in the past 6 months Have a Claudin 18.2 positive tumor (Claudin 18.2 is a tumor marker often seen in stomach and ...

Phase

Selenium and Vitamin E in Preventing Cancer Progression and Recurrence in Patients With Early-Stage Bladder Cancer

OBJECTIVES: - To investigate whether selenium and/or vitamin E (α-tocopherol) supplementation reduces the risk of recurrence and progression. OUTLINE: This is a multicenter study. Patients are stratified by recurrence risk group (high vs intermediate) and treatment center and randomized to 1 of 4 treatment arms. - Arm I: Patients receive ...

Phase

Quality of Life in Patients With Bladder Cancer

OBJECTIVES: - To study the effects of recurrence and progression on health-related quality of life (HRQL). - To study the effects of repeat cystoscopy on HRQL. - To study the patients' assessments of a hypothetical prognostic model and how this affects their preference for the mode of surveillance. OUTLINE: This ...

Phase

Different Factors Affecting Patients With Newly Diagnosed Bladder Cancer

OBJECTIVES: - To assess the effect of lifestyle factors (e.g., smoking, dietary habits, fluid intake, or environmental exposures) on the recurrence and progression of bladder cancer. - To assess the impact of selenium and/or vitamin E on the progression and recurrence of bladder cancer. - To study health-related quality of ...

Phase

Adjuvant Intraarterial Chemotherapy Following Surgery to Treat Locally Advanced Bladder Cancer

For locally advanced bladder cancer patients, tumor relapse rates after radial cystectomy were even as high as 50%-62%.Five-year disease-specific survival and OS rates in the organ-confined disease (defined as pT3a) were 78.9% and 68%, respectively. For the non-organ-confined disease (defined as pT3b or higher), the rates were about 36.8% and ...

Phase

Effect of Dietary Lifestyle and Environmental Factors on Patients With Early-Stage Bladder Cancer

OBJECTIVES: - To examine if common and potentially modifiable dietary, lifestyle, and environmental exposures affect the risk of recurrence and progression in bladder cancer. OUTLINE: This is a multicenter study. Detailed information will be collected about the patients' lifestyle and their exposure to risk factors associated with bladder cancer using ...

Phase