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Cancer/Tumors Clinical Trials

A listing of Cancer/Tumors medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (7708) clinical trials

HFHS-1801-A Pilot Study of Immunotherapy as Consolidation Therapy for Patients With Recurrent Head and Neck Cancer

Approximately 30-40% of patients treated with a curative intent for locally advanced squamous cell carcinoma of the head and neck cancer will experience an isolated loco-regional recurrence or a second primary tumor in the previously radiated tissues1-5. Patients with recurrent head and neck cancer frequently recur locally and are still ...

Phase N/A

A Study to Test Different Doses of BI 891065 Alone and in Combination With BI 754091 in Asian Patients With Different Types of Advanced Cancer (Solid Tumours)

The primary objective of this trial is: Part A To determine the Maximum tolerated dose (MTD) and/or the recommended dose (RD) of BI 891065 monotherapy for further development in Asian patients with advanced solid tumours Part B To determine the MTD and/or the RD of BI 891065 in combination with ...

Phase

Molecular Genetics Studies of Cancer Patients and Their Relatives

PRIMARY OBJECTIVES: I. To identify rare cancer patients and families in whom the pattern of disease suggests a genetic susceptibility to cancer or other etiology suggestive of a carcinogenic exposure and to characterize the underlying predisposition. II. To determine the contribution of heredity (genotype) and biomarkers to clinical outcome (phenotype, ...

Phase N/A

Therapy for High-Risk HPV 16-Positive Oropharynx Cancer Patients

Objectives Primary Objectives: To determine whether combination immune checkpoint inhibitor, alone or together with a DNA vaccine will result in clearance of HPV biomarkers for patients at risk of disease progression. Secondary Objective(s): To evaluate the time to progression among patients with detectable HPV DNA when treated with the durvalumab/MEDI0457 ...

Phase

RECELL System Combined With Meshed Autograft for Reduction of Donor Skin Harvesting in Soft Tissue Reconstruction

A prospective randomized within-subject controlled study to compare the clinical performance of conventional autografting with and without the RECELL system on acute non-burn full-thickness skin defects.

Phase N/A

A Study of Pemigatinib in Non-muscle Invasive Bladder Cancer Patients With Recurrent Low- or Intermediate-Risk Tumors

It is a single-arm phase 2 window of opportunity study to assess the antineoplastic activity of pemigatinib in non-muscle invasive bladder cancer (NMIBC) patients with recurrent tumors and a prior history of low- or intermediate-risk NMIBC tumors. Enrolled patients will receive pemigatinib for 4-6 weeks prior to standard of care ...

Phase

Treatment of Recurrent Bladder Cancer With Dendritic Cells

Treatment of recurrent bladder cancer with dendritic cells

Phase

A Study of LY3499446 in Participants With Advanced Solid Tumors With KRAS G12C Mutation

The reason for this study is to see if the study drug LY3499446 is safe and effective in participants with solid tumors with KRAS G12C mutation.

Phase

Ovarian Cancer Treatment With a Liposome Formulated mRNA Vaccine in Combination With (Neo-)Adjuvant Chemotherapy

This is a first-in-human, open label phase I intra-patient dose escalation study (vaccination 1 and 2) in OC patients with primary disease eligible for SoC treatment with neo-adjuvant chemotherapy, i.e. 3 cycles carboplatin/paclitaxel, interval surgery and 3 additional cycles carboplatin/paclitaxel. OC patients will be vaccinated prior and during (neo)-adjuvant chemotherapy ...

Phase

A Study of CART-TnMUC1 in Patients With TnMUC1-Positive Advanced Cancers

The study is comprised of two parallel Phase 1 Arms (solid tumors and multiple myeloma) and a Phase 1a expansion in patients with TnMUC1+ platinum-resistant ovarian cancer. The Phase 1 portion of the study is designed to identify the dose and regimen of CART-TnMUC1 cells that can be safely administered ...

Phase