Acute Respiratory Distress Syndrome (ARDS) Clinical Trials

A listing of Acute Respiratory Distress Syndrome (ARDS) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 150 clinical trials
Safety and Effectiveness of Placental Derived Exosomes and Umbilical Cord Mesenchymal Stem Cells in Moderate to Severe Acute Respiratory Distress Syndrome (ARDS) Associated With the Novel Corona Virus Infection (COVID-19)

Recent advances have been made in prevention of the viral infection via vaccines but there is still need for effective treatment options for patients. Novel therapies need to be developed to further improve clinical outcomes. The biggest medical challenge in the response to COVID-19 is ARDS requiring hospitalization in an …

  • 0 views
  • 28 Oct, 2022
  • 1 location
Regenerative Medicine for COVID-19 and Flu-Elicited ARDS Using Lomecel-B (RECOVER)

A Phase I, double- blinded, randomized, placebo- controlled study to test the safety of Lomecel-B in Adults suffering from mild to severe acute respiratory distress syndrome (ARDS) due to COVID

assisted breathing
edema
bilateral pulmonary infiltrates
acute respiratory distress
positive end expiratory pressure
  • 0 views
  • 07 Oct, 2021
  • 3 locations
Safety and Tolerability of Adaptive Escalating Multiple Doses (Three Times Daily) of a Soluble Guanylate Cyclase (sGC) Activator Inhale, BAY 1211163, as Inhalation in Intubated and Mechanically Ventilated Adult Patients With Moderate and Severe Acute Respiratory Distress Syndrome (ARDS). A Pilot (Phase Ib), First in Patient, Open Label Study

With this study researchers want to find the highest safe dose of the soluble Guanylate Cyclase (sGC) Activator, BAY 1211163 and how safe and well the study drug works. Furthermore researchers want to gather information on the way the body absorbs, distributes and gets rid of the study drug given …

assisted breathing
assisted ventilation
positive end expiratory pressure
mechanical ventilation
pao2
  • 0 views
  • 24 Oct, 2022
  • 2 locations
Infants With Severe Acute Respiratory Distress Syndrome: The Prone Trial

The main objective is to determine the short-term effect of prone positioning in infants with infection-associated severe acute respiratory distress syndrome. The investigators compare oxygenation parameters and measurements from electrical impedance tomography (EIT) and lung ultrasonography (LUS) in mechanically ventilated infants in prone position versus supine position after surfactant administration.

  • 0 views
  • 04 Oct, 2022
  • 1 location
MultiStem Administration for COVID-19 Induced ARDS (MACoVIA) (MACoVIA)

subjects with moderate to severe Acute Respiratory Distress Syndrome (ARDS) due to pathogens including COVID-19.

pneumonia
covid-19
acute respiratory distress
  • 73 views
  • 05 Mar, 2022
  • 4 locations
Early Use of Prone Position in ECMO for Severe ARDS

Extracorporeal membrane oxygenation (ECMO) is widely used in the salvage treatment of critical acute respiratory distress syndrome (ARDS). However, reduce lung injury, accelerate lung recovery

assisted breathing
positive end expiratory pressure
acute respiratory distress
pneumonia
pao2
  • 2 views
  • 25 Feb, 2022
  • 1 location
Paediatric Ards Neuromuscular Blockade Study (PAN)

Paediatric acute respiratory distress syndrome (ARDS) is a manifestation of severe, life-threatening lung injury. Care for paediatric patient is mainly supportive and based on what works in

assisted breathing
neuromuscular blocking agents
positive end expiratory pressure
acute respiratory distress
mechanical ventilation
  • 4 views
  • 21 Feb, 2022
  • 1 location
Mesenchymal Stromal Cells For Acute Respiratory Distress Syndrome (STAT)

Stromal Cells (hMSCs) infusion in patients with Acute Respiratory Distress Syndrome (ARDS). This study is the extension of the Phase 1 pilot study (NCT01775774) and Phase 2a study (NCT02097641).

assisted breathing
edema
bilateral pulmonary infiltrates
intermittent positive pressure ventilation
pao2/fio2 ratio
  • 5 views
  • 07 Oct, 2022
  • 7 locations
Safety and Preliminary Efficacy of Sequential Multiple Ascending Doses of Solnatide to Treat Pulmonary Permeability Oedema in Patients With Moderate-to-severe ARDS

This phase IIb, randomized, placebo-controlled, double-blind, dose escalation study will assess the local and systemic safety of 7 days orally inhaled sequential multiple ascending doses of solnatide in patients with pulmonary permeability oedema and moderate-to-severe ARDS and review potential efficacy endpoints for a future phase III pivotal trial.

assisted breathing
edema
effusions
positive end expiratory pressure
fluid overload
  • 19 views
  • 04 Oct, 2022
  • 8 locations
Effect of Two Different Doses of Dexamethasone in Patients With ARDS and COVID-19 (REMED)

REMED is a prospective, phase II, open-label, randomised controlled trial testing superiority of dexamethasone 20 mg vs 6 mg. The trial aims to be pragmatic, i.e. designed to evaluate the effectiveness of the intervention in conditions that are close to real-life routine clinical practice. The study is multi-centre and will …

extubation
covid-19
dexamethasone
  • 0 views
  • 10 Mar, 2022
  • 1 location