Cervical Intraepithelial Neoplasia Clinical Trials

A listing of Cervical Intraepithelial Neoplasia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 98 clinical trials
Pembrolizumab and Olaparib in Cervical Cancer Patients

The study is a non-randomized, open-label phase II clinical trial to test the investigational combination of the drug pembrolizumab with the drug olaparib in patients diagnosed with advanced or recurrent cervical carcinoma after standard chemotherapy.

measurable disease
carcinoma
recurrent cervical cancer
pd-1 inhibitor
pembrolizumab
  • 7 views
  • 02 May, 2022
  • 1 location
Contrast-Enhanced Ultrasound Imaging Scan for the Detection of Sentinel Lymph Nodes in Patients With Cervical, Vaginal, or Vulvar Cancer

This clinical trial compares the use of ultrasound for the detection of sentinel lymph nodes (SLNs) to the standard of care (which varies depending on cancer treatment). The ultrasound contrast agent is called Sonazoid and it consists of tiny gas-filled bubbles about the side of red blood cells. Diagnostic procedures, …

cancer treatment
diagnostic procedures
lab tests
cancer
primary cancer
  • 0 views
  • 28 Jul, 2022
  • 1 location
A Clinical Study of LM103 Injection in the Treatment of Advanced Solid Tumors

This is a single-arm, open-label, exploratory study to evaluate safety and efficacy of LM103 Injection in patients with advanced solid tumors. The purpose of this study is to evaluate the safety and tolerability, antitumor activity and immunoreactivity.

metastasis
liver metastasis
lung cancer
cancer
neutrophil count
  • 0 views
  • 11 Aug, 2022
  • 1 location
Comparison of Acute Toxicities Between Patients Treated With Protons or Intensity Modulated Radiation Therapy After Surgery for the Treatment of Endometrial or Cervical Cancer

This early phase I trial compares the side effects between patients treated with proton radiation therapy versus intensity modulated radiation therapy after surgery for the treatment of endometrial or cervical cancer. Radiation therapy uses high energy protons or x-rays to kill tumor cells and shrink tumors. Using quality of life …

carcinoma
x-rays
hysterectomy
tumor cells
endometriosis
  • 0 views
  • 09 Jul, 2022
  • 3 locations
PD-1 Antibody Plus Chemoradiotherapy for IB2-IIIB Cervical Cancer

This study is a single-center, single-arm, open-phase II clinical study, the main purpose of which is to evaluate the effectiveness and safety of camrelizumab combined with concurrent chemoradiotherapy for early and locally advanced cervical cancer, i.e., FIGO 2018 IB2-IIIB cervical cancer. Eligible subjects will be given cisplatin and radiotherapy, for …

adenosquamous carcinoma
carcinoma
adenocarcinoma
chemoradiotherapy
concurrent chemoradiation
  • 0 views
  • 05 May, 2022
  • 1 location
A Study of XmAb20717 in Patients With Selected Advanced Gynecologic and Genitourinary Malignancies

This is a Phase 2, multicenter, two-stage, open-label, parallel-group study designed to evaluate the efficacy and safety of XmAb20717 in patients with selected advanced gynecologic and genitourinary malignancies.

ovarian epithelial carcinoma
metastasis
carcinosarcoma
measurable disease
serous adenocarcinoma
  • 0 views
  • 09 Aug, 2022
  • 2 locations
Evaluation of cfDNA as a Marker of Response in Rectal Cancer

fragments, % of mutation frequency (CIN, APC, p53, MSI, KRAS, BRAF, EGFR, cKIT) and next-generation sequencing of tumour biopsy and surgical specimens. This study will serve as the feasibility of a

adenocarcinoma of rectum
EGFR
curative surgery
BRAF
KRAS
  • 0 views
  • 02 Mar, 2022
  • 1 location
Safety and Efficacy of Recombinant Oncolytic Adenovirus L-IFN Injection in Relapsed/Refractory Solid Tumors Clinical Study (YSCH-01)

This is an open-label, dose escalation study of the safety and tolerability of Recombinant oncolytic adenovirus L-IFN injection(YSCH-01) when administered via intratumoral injection in patients with advanced solid tumors. The purpose of this study is to assess the safety and tolerability of Recombinant L-IFN adenovirus injectionand to determine the recommended …

metastasis
liver metastasis
measurable disease
platelet count
absolute neutrophil count
  • 0 views
  • 22 Mar, 2022
  • 1 location
Biospecimen Collection and Testing for the Prevalence of Anal Dysplasia and Anal Cancer in Patients With Cervical Vaginal and Vulvar Dysplasia and Cancer

This trial studies the prevalence of anal dysplasia and anal cancer in patients with cervical, vaginal, and vulvar dysplasia and cancer. Studying samples collected from patients in the laboratory may help doctors learn more about the human papillomavirus and how often anal cancer occurs in patients with cervix, vagina, or …

hsil
squamous cell carcinoma
human papillomavirus
cancer
carcinoma
  • 96 views
  • 26 Jan, 2021
  • 1 location
Prospective Exploratory Study of FAPi PET/CT With Histopathology Validation in Patients With Various Cancers (FAPI PET RDRC)

This exploratory study investigates how an imaging technique called 68Ga-FAPi-46 PET/CT can determine where and to which degree the FAPI tracer (68Ga-FAPi-46) accumulates in normal and cancer tissues in patients with cancer. Because some cancers take up 68Ga-FAPi-46 it can be seen with PET. FAP stands for Fibroblast Activation Protein. …

bladder cancer
dotatate
thymus cancer
metastasis
pet/ct scan
  • 0 views
  • 23 Jul, 2022
  • 1 location