Cervical Intraepithelial Neoplasia Clinical Trials

A listing of Cervical Intraepithelial Neoplasia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 98 clinical trials
Concomitant HPV Vaccination and HPV Screening HPV Infection and Cervical Cancer in Sweden

The study aims to evaluate whether organised, concomitant HPV vaccination and HPV screening offered to all resident women aged 22-27 will result in a more rapid elimination of HPV infection in Sweden. This objective will be examined at the population level.

human papilloma virus vaccine
gardasil
  • 0 views
  • 25 Sep, 2021
  • 1 location
Phase 1/2a/3 Evaluation of Adding AL3818 to Standard Platinum-Based Chemotherapy in Subjects With Recurrent or Metastatic Endometrial, Ovarian, Fallopian, Primary Peritoneal or Cervical Carcinoma (AL3818-US-002) (AL3818)

This trial is a Phase 1b/2a/3 trial designed to evaluate the safety and efficacy of adding oral AL3818 (Anlotinib, INN: Catequentinib), a Dual Receptor Tyrosine Kinase Inhibitor, to standard platinum-based chemotherapy concurrently in Subjects with Recurrent or Metastatic Endometrial, Ovarian, Fallopian, Primary Peritoneal or Cervical Carcinoma.

adenocarcinoma
cancer
carcinoma
cancer of the ovary
carboplatin
  • 9 views
  • 21 Jul, 2022
  • 14 locations
Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-158/KEYNOTE-158)

In this study, participants with multiple types of advanced (unresectable and/or metastatic) solid tumors who have progressed on standard of care therapy will be treated with pembrolizumab (MK-3475).

adenocarcinoma
cancer
carcinoma
small intestine
squamous cell carcinoma of cervix
  • 15 views
  • 23 Jul, 2022
  • 24 locations
Molecular Analysis for Therapy Choice (MATCH)

This phase II MATCH trial studies how well treatment that is directed by genetic testing works in patients with solid tumors or lymphomas that have progressed following at least one line of standard treatment or for which no agreed upon treatment approach exists. Genetic tests look at the unique genetic …

binimetinib
sunitinib malate
prednisone
osimertinib
tenofovir
  • 6585 views
  • 14 Sep, 2022
  • 911 locations
Bright Ideas - CIN Feasibility Study

In this study investigators will determine the feasibility of a future trial comparing chemotherapy-induced nausea control in children with ALL receiving oral 6-mercaptopurine who do and do not receive problem-solving skill training. This is a novel approach to controlling an important and common treatment-related symptom.

  • 0 views
  • 12 Aug, 2022
  • 2 locations
Pembrolizumab for the Treatment of Cervical Intraepithelial Neoplasia

This phase II trial studies the effect of pembrolizumab on cervical intraepithelial neoplasia. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system

cancer
carcinoma
loop electrosurgical excision procedure
  • 21 views
  • 23 Mar, 2022
  • 1 location
A Two-Cohort Randomized Phase 2 Trial of the IRX-2 Regimen in Women With Squamous Cervical Intraepithelial Neoplasia 3 (CIN 3) or Vulvar Intraepithelial Neoplasia 3 (VIN 3)

This randomized phase II trial studies how well an IRX-2 Regimen works in treating women with cervical squamous intraepithelial neoplasia 3 or squamous vulvar intraepithelial neoplasia 3. The IRX-2 Regimen consists of a single dose of cyclophosphamide, followed by 21 days of indomethacin, zinc-containing multivitamins, and omeprazole. IRX-2, a human …

  • 34 views
  • 19 Sep, 2022
  • 2 locations
Open-Label Extension Study of Patients Previously Enrolled in Study CIN-107-124

This is a Phase 2, multicenter, open-label extension (OLE) study to evaluate the long-term safety, tolerability, and effectiveness of CIN-107 for up to 52 weeks in patients with HTN who have

antihypertensive drugs
  • 0 views
  • 29 Jul, 2022
  • 15 locations
HPV DNA Vaccine Via Electroporation for HPV16 Positive Cervical Neoplasia

electroporation to both HIV- or HIV+ adult female subjects (≥ 19 years), with biopsy confirmed cervical intraepithelial (CIN) II or III that is human papillomavirus (HPV) 16+.

colposcopy
human papillomavirus
cervical intraepithelial neoplasia grade 2
dna vaccine
human papillomavirus dna
  • 0 views
  • 29 Apr, 2022
  • 2 locations
Large Loop Excision of the Transformation Zone (LLETZ) With Versus Without Intraoperative Application of Lugol's Iodine in Women With Cervical Dysplasia: a Prospective Randomized Trial (LLETZ-IOLI)

worldwide standard surgical procedure for conization. There is risk of local persistence of the precancerous lesion if the cervical dysplasia is not completely removed. To minimize this, the iodine test can

colposcopy
cancer
cin 3
cin 1
smear
  • 0 views
  • 22 Sep, 2022
  • 1 location