Cervical Dysplasia Clinical Trials

A listing of Cervical Dysplasia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 98 clinical trials
Concomitant HPV Vaccination and HPV Screening HPV Infection and Cervical Cancer in Sweden

The study aims to evaluate whether organised, concomitant HPV vaccination and HPV screening offered to all resident women aged 22-27 will result in a more rapid elimination of HPV infection in Sweden. This objective will be examined at the population level.

gardasil
human papilloma virus vaccine
  • 0 views
  • 25 Sep, 2021
  • 1 location
Phase 1/2a/3 Evaluation of Adding AL3818 to Standard Platinum-Based Chemotherapy in Subjects With Recurrent or Metastatic Endometrial, Ovarian, Fallopian, Primary Peritoneal or Cervical Carcinoma (AL3818-US-002) (AL3818)

This trial is a Phase 1b/2a/3 trial designed to evaluate the safety and efficacy of adding oral AL3818 (Anlotinib, INN: Catequentinib), a Dual Receptor Tyrosine Kinase Inhibitor, to standard platinum-based chemotherapy concurrently in Subjects with Recurrent or Metastatic Endometrial, Ovarian, Fallopian, Primary Peritoneal or Cervical Carcinoma.

serum pregnancy test
renal function tests
carboplatin/paclitaxel
doxorubicin
topotecan
  • 9 views
  • 21 Jul, 2022
  • 14 locations
Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-158/KEYNOTE-158)

In this study, participants with multiple types of advanced (unresectable and/or metastatic) solid tumors who have progressed on standard of care therapy will be treated with pembrolizumab (MK-3475).

small cell carcinoma
vulvar carcinoma
line of therapy
solid tumors
pembrolizumab
  • 15 views
  • 23 Jul, 2022
  • 24 locations
Molecular Analysis for Therapy Choice (MATCH)

This phase II MATCH trial studies how well treatment that is directed by genetic testing works in patients with solid tumors or lymphomas that have progressed following at least one line of standard treatment or for which no agreed upon treatment approach exists. Genetic tests look at the unique genetic …

osimertinib
ipatasertib
sunitinib
antiretroviral therapy
other malignancy
  • 6585 views
  • 14 Sep, 2022
  • 911 locations
Bright Ideas - CIN Feasibility Study

In this study investigators will determine the feasibility of a future trial comparing chemotherapy-induced nausea control in children with ALL receiving oral 6-mercaptopurine who do and do not receive problem-solving skill training. This is a novel approach to controlling an important and common treatment-related symptom.

  • 0 views
  • 12 Aug, 2022
  • 2 locations
A Two-Cohort Randomized Phase 2 Trial of the IRX-2 Regimen in Women With Squamous Cervical Intraepithelial Neoplasia 3 (CIN 3) or Vulvar Intraepithelial Neoplasia 3 (VIN 3)

This randomized phase II trial studies how well an IRX-2 Regimen works in treating women with cervical squamous intraepithelial neoplasia 3 or squamous vulvar intraepithelial neoplasia 3. The IRX-2 Regimen consists of a single dose of cyclophosphamide, followed by 21 days of indomethacin, zinc-containing multivitamins, and omeprazole. IRX-2, a human …

  • 34 views
  • 19 Sep, 2022
  • 2 locations
Pembrolizumab for the Treatment of Cervical Intraepithelial Neoplasia

This phase II trial studies the effect of pembrolizumab on cervical intraepithelial neoplasia. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system

carcinoma
cancer
loop electrosurgical excision procedure
  • 21 views
  • 23 Mar, 2022
  • 1 location
Large Loop Excision of the Transformation Zone (LLETZ) With Versus Without Intraoperative Application of Lugol's Iodine in Women With Cervical Dysplasia: a Prospective Randomized Trial (LLETZ-IOLI)

worldwide standard surgical procedure for conization. There is risk of local persistence of the precancerous lesion if the cervical dysplasia is not completely removed. To minimize this, the iodine test can

cone biopsy
loop electrosurgical excision procedure
cin 3
cin 1
large loop excision of transformation zone
  • 0 views
  • 22 Sep, 2022
  • 1 location
Comparison of Two Surgical Approaches in the Treatment of Cervical Dysplasia: Complete Removal of the Transformation Zone (LLETZ) Versus Isolated Resection of the Colposcopically Visible Lesion (LEEP)

Cervical dysplasia is the precursor of cervical cancer. LEEP and LLETZ are standard surgical procedures to treat cervical dysplasia. There is no direct head-to-head comparison between LEEP and

loop electrosurgical excision procedure
large loop excision of transformation zone
squamous intraepithelial lesion
loop electrosurgical excision
dysplasia
  • 0 views
  • 21 Sep, 2022
  • 1 location
Open-Label Extension Study of Patients Previously Enrolled in Study CIN-107-124

This is a Phase 2, multicenter, open-label extension (OLE) study to evaluate the long-term safety, tolerability, and effectiveness of CIN-107 for up to 52 weeks in patients with HTN who have

antihypertensive drugs
  • 0 views
  • 29 Jul, 2022
  • 15 locations