Gliomas Clinical Trials

A listing of Gliomas medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 113 clinical trials
Chimeric Antigen Receptor (CAR) T Cells With a Chlorotoxin Tumor-Targeting Domain for the Treatment of MPP2+ Recurrent or Progressive Glioblastoma

This phase I trial studies the side effects and best dose of chimeric antigen receptor (CAR) T cells with a chlorotoxin tumor-targeting domain in treating patients with MPP2+ glioblastoma that has come back (recurrent) or that is growing, spreading, or getting worse (progressive). Vaccines made from a gene-modified virus may …

neutrophil count
tumor cells
mpp2
karnofsky performance status
serum pregnancy test
  • 1 views
  • 26 Jun, 2021
  • 1 location
Non-Invasive Focused Ultrasound (FUS) With Oral Panobinostat in Children With Progressive Diffuse Midline Glioma (DMG)

effects in the patient. The primary purpose of this study is to evaluate the feasibility of safely opening the BBB in children with progressive diffuse midline gliomas (DMG) treated with oral

  • 0 views
  • 28 Jul, 2021
  • 1 location
Selinexor in Treating Younger Patients With Recurrent or Refractory Solid Tumors or High-Grade Gliomas

This phase I trial studies the side effects and best dose of selinexor in treating younger patients with solid tumors or central nervous system (CNS) tumors that have come back (recurrent) or do not respond to treatment (refractory). Drugs used in chemotherapy, such as selinexor, work in different ways to …

platelet count
stem cell infusion
cns tumors
myelosuppressive chemotherapy
nervous
  • 47 views
  • 28 Jul, 2021
  • 14 locations
A Study of GNC-039 a Tetra-specific Antibody in Participants With Relapsed/Refractory or Metastatic Solid Tumors

In this study, the safety, tolerability and preliminary effectiveness of GNC-039 in patients with relapsed/refractory or metastatic glioma or other solid tumors will be investigated to assess

platelet count
renal function
neutrophil count
MRI
measurable disease
  • 0 views
  • 25 Jun, 2021
  • 1 location
Dose Escalation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma

Background A glioblastoma is a tumor in the brain. It is treated with surgery, chemotherapy and radiation therapy. However, most people s tumors come back after therapy. When the tumor grows back, surgery or chemotherapy may not be possible or may no longer work. Repeat radiation therapy or re-irradiation, is …

cytotoxic chemotherapy
recurrent glioblastoma
temozolomide
combined modality therapy
MRI
  • 41 views
  • 31 Jul, 2021
  • 1 location
Selinexor (KPT-330) in Combination With Temozolomide and Radiation Therapy in Patients With Newly Diagnosed Glioblastoma

Background Glioblastoma is a type of brain cancer. Treatments include radiation, chemotherapy, and surgery. But survival rates are poor. Researchers think that the drug selinexor, when combined with chemotherapy and radiation, might help. Objective To learn the highest dose of selinexor that people with brain cancer can tolerate when given …

platelet count
temozolomide
neutrophil count
brain tumor
cancer
  • 43 views
  • 31 May, 2021
  • 1 location
Phase I Study of APX005M in Pediatric CNS Tumors

(progressive), or newly diagnosed diffuse intrinsic pontine glioma. APX005M can trigger activation of B cells, monocytes, and dendritic cells and stimulat cytokine release from lymphocytes and monocytes

dipg
myelosuppressive chemotherapy
neutrophil count
mri of spine
malignant central nervous system tumor
  • 165 views
  • 26 Jan, 2021
  • 11 locations
Serial MR Imaging and MR Spectroscopic Imaging for the Characterization of Lower Grade Glioma

This trial studies how well serial magnetic resonance (MR) imaging and MR spectroscopic imaging work in characterizing lower grade glioma. Diagnostic procedures, such as MR imaging and MR

  • 0 views
  • 25 Jan, 2021
  • 1 location
A Study of PRT811 in Participants With Advanced Solid Tumors CNS Lymphoma and Gliomas

This is a Phase 1 dose-escalation study of PRT811, a protein arginine N-methyltransferase (PRMT) 5 inhibitor, in subjects with advanced cancers and high-grade gliomas who have exhausted

cancer
solid tumour
  • 7 views
  • 01 Aug, 2021
  • 8 locations
A Longitudinal Assessment of Tumor Evolution in Patients With Brain Cancer

before standard therapy with radiation and temozolomide in patients with newly diagnosed high grade glioma. Additional aims of the study are to: Find out side effects (good and bad

  • 2 views
  • 26 Apr, 2021
  • 1 location