Gliomas Clinical Trials

A listing of Gliomas medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 112 clinical trials
D2C7-IT With Atezolizumab for Recurrent Gliomas

with recurrent World Health Organization (WHO) grade IV malignant glioma at the Preston Robert Tisch Brain Tumor Center (PRTBTC) at Duke.

atezolizumab
brain tumor
estrogen
prothrombin
brain mri
  • 0 views
  • 16 May, 2021
  • 1 location
A Pilot Study of Glioma Associated Antigen Vaccines in Conjunction With Poly-ICLC in Pediatric Gliomas

The overall objective of this pilot study is to collect immunological and safety data following administration of vaccinations with HLA-A2. This data will be used to decide whether a larger study of clinical efficacy is warranted.

  • 11 views
  • 24 Jan, 2021
  • 1 location
Oncolytic Adenovirus DNX-2401 in Treating Patients With Recurrent High-Grade Glioma

This phase I trial studies best dose and side effects of oncolytic adenovirus DNX-2401 in treating patients with high-grade glioma that has come back (recurrent). Oncolytic adenovirus DNX-2401

thromboplastin
anaplastic astrocytoma
astrocytoma
recurrent malignant glioma
MRI
  • 2 views
  • 07 May, 2021
  • 1 location
Genetically Engineered HSV-1 Phase 1 Study for the Treatment of Recurrent Malignant Glioma

To determine the safety and tolerability of the maximum dose for laboratory engineered Herpes Simplex Virus-1 in patients who would not be eligible for surgical resection of recurrent glioma To

  • 139 views
  • 09 Jul, 2021
  • 1 location
GD2 CAR T Cells in Diffuse Intrinsic Pontine Gliomas(DIPG) & Spinal Diffuse Midline Glioma(DMG)

pontine glioma (DIPG) or spinal H3K27M-mutant diffuse midline glioma (DMG). H3K27Mmutant testing will occur as part of standard of care prior to enrollment.

  • 0 views
  • 14 May, 2021
  • 1 location
A Phase I Dose Escalation Study for Patients With Recurrent Malignant Gliomas

This is a clinical trial (a type of research study). Clinical trials include only patients who choose to take part. You are being asked to take part in this study because you have a brain tumor that continued to grow despite prior therapy. Currently, there is no known effective treatment …

  • 7 views
  • 07 Nov, 2020
  • 1 location
A Study of BXQ-350 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) or Diffuse Midline Glioma (DMG)

This study will evaluate the safety of BXQ-350 and determine the maximum tolerated dose (MTD) in children with newly diagnosed DIPG or DMG. All patients will receive BXQ-350 by intravenous (IV) infusion and radiation therapy. The study is divided into two parts: Part 1 will enroll patients at increasing dose …

  • 0 views
  • 28 Jul, 2021
  • 3 locations
Adoptive Cellular Therapy in Pediatric Patients With High-grade Gliomas

vaccine which we hope will stimulate T-cells to kill tumor cells and leave normal cells alone. High grade gliomas (HGGs) are very aggressive and difficult for the body's immune system to attack

cellular therapy
malignant glioma
corticosteroids
neutrophil count
tumor cells
  • 13 views
  • 18 Jul, 2021
  • 2 locations
AMPLIFYing NEOepitope-specific VACcine Responses in Progressive Diffuse Glioma

blockade in post-treatment tumor tissue. The study will enroll 48 evaluable patients (presumably, 60 in total) with IDH1R132H-mutated gliomas with an unfavorable molecular profile (no 1p/19q co-deletion

  • 0 views
  • 15 Mar, 2021
  • 10 locations
HUMC 1612: Optune NovoTTF-200A System

The purpose of this study is to determine if the Optune NovoTTF-200A device can be safely used in combination with chemotherapy in pediatric patients with recurrent high-grade glioma and

renal function
tumor progression
anaplastic astrocytoma
astrocytoma
recurrent malignant glioma
  • 3 views
  • 24 Jan, 2021
  • 2 locations