Gliomas Clinical Trials

A listing of Gliomas medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 112 clinical trials
Personalized Vaccine for Patients With Recurrent Malignant Glioma

malignant glioma.

recurrent malignant glioma
measurable disease
malignant glioma
  • 0 views
  • 05 Jul, 2021
  • 1 location
D2C7 for Adult Patients With Recurrent Malignant Glioma

(CED) to recurrent World Health Organization (WHO) grade III and IV malignant glioma patients, and/or to determine what dose will be considered in a Phase II trial. Patients with recurrent WHO grade

immunotoxin
brain mri
prothrombin
aptt
karnofsky performance status
  • 132 views
  • 08 Apr, 2021
  • 1 location
A Phase 1b Study of PTC596 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma and High Grade Glioma

any, these drugs have on children and young adults with brain tumors. The investigators are asking people to be in this research study who have been diagnosed with a high grade glioma (HGG

astrocytoma
diffuse intrinsic pontine glioma
renal function
total resection
anticonvulsants
  • 1 views
  • 27 Mar, 2021
  • 9 locations
Neo-adjuvant Evaluation of Glioma Lysate Vaccines in WHO Grade II Glioma

This is a pilot neoadjuvant vaccine study in adults with WHO grade II glioma, for which surgical resection of the tumor is clinically indicated. Co-primary objectives are to determine: 1) the

astrocytoma
poly iclc
karnofsky performance status
initial diagnosis
oligoastrocytoma
  • 111 views
  • 12 Jun, 2021
  • 1 location
Convection-enhanced Delivery of OS2966 for Patients With High-grade Glioma Undergoing a Surgical Resection

The primary goal of this Phase 1 study is to determine if a new investigational drug, OS2966, when delivered directly to the brain of adult participants with recurrent/progressive high-grade

cancer
brain tumor
aptt
MRI
bevacizumab
  • 0 views
  • 20 Apr, 2021
  • 1 location
A Study of the Treatment of Recurrent Malignant Glioma With rQNestin34.5v.2

This research study is evaluating an investigational drug, an oncolytic virus called rQNestin34.5v.2. This research study is a Phase I clinical trial, which tests the safety of an investigational drug and also tries to define the appropriate dose of the investigational drug as a possible treatment for this diagnosis of …

low grade glioma
astrocytoma
cyclophosphamide
therapeutic agent
astrocytoma, anaplastic
  • 58 views
  • 28 Jan, 2021
  • 2 locations
Genetically Modified T-cells in Treating Patients With Recurrent or Refractory Malignant Glioma

This phase I trial studies the side effects and best dose of genetically modified T-cell immunotherapy in treating patients with malignant glioma that has come back (recurrent) or has not

x-rays
international normalized ratio
karnofsky performance status
MRI
bevacizumab
  • 60 views
  • 19 Feb, 2021
  • 2 locations
Personalized Chimeric Antigen Receptor T Cell Immunotherapy for Patients With Recurrent Malignant Gliomas

without anti-PDL1 antibody) personalized immunotherapy for patients with recurrent malignant gliomas based on the expression of tumor specific/associated antigens (EGFRVIII, IL13R2, Her-2, EphA2, CD133

erbb2
immunohistochemistry
prothrombin
karnofsky performance status
growth factor
  • 13 views
  • 20 Jun, 2021
  • 1 location
ONC201 in Pediatric H3 K27M Gliomas

/refractory H3 K27M gliomas. Arm A will define the RP2D for single agent ONC201 in pediatric patients with glioma who are positive for the H3 K27M mutation (positive testing in CLIA laboratory) and have

re-irradiation
initial diagnosis
diffuse intrinsic pontine glioma
nitrosoureas
renal function
  • 85 views
  • 16 May, 2021
  • 8 locations
Hyperpolarized Imaging in Diagnosing Participants With Glioma

This pilot trial studies the side effects of hyperpolarized carbon C 13 pyruvate magnetic resonance imaging (MRI) in diagnosing participants with glioma. Diagnostic procedures, such as

renal function
MRI
temozolomide
karnofsky performance status
cancer
  • 3 views
  • 25 Jan, 2021
  • 1 location