Gliomas Clinical Trials

A listing of Gliomas medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 114 clinical trials
Terameprocol in Treating Patients With Recurrent High Grade Glioma

This phase I trial studies the side effects and best dose of terameprocol in treating patients with high-grade glioma that has come back. Drugs used in chemotherapy, such as terameprocol, work

  • 18 views
  • 25 Apr, 2021
  • 10 locations
D2C7 for Adult Patients With Recurrent Malignant Glioma

(CED) to recurrent World Health Organization (WHO) grade III and IV malignant glioma patients, and/or to determine what dose will be considered in a Phase II trial. Patients with recurrent WHO grade

recurrent tumor
karnofsky performance status
neutrophil count
platelet count
aptt
  • 132 views
  • 08 Apr, 2021
  • 1 location
A Phase 1b Study of PTC596 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma and High Grade Glioma

any, these drugs have on children and young adults with brain tumors. The investigators are asking people to be in this research study who have been diagnosed with a high grade glioma (HGG

recurrent tumor
brain tumor
anticonvulsants
cancer
platelet count
  • 1 views
  • 27 Mar, 2021
  • 9 locations
Convection-enhanced Delivery of OS2966 for Patients With High-grade Glioma Undergoing a Surgical Resection

The primary goal of this Phase 1 study is to determine if a new investigational drug, OS2966, when delivered directly to the brain of adult participants with recurrent/progressive high-grade

brain tumor
cancer
platelet count
neutrophil count
renal function
  • 0 views
  • 20 Apr, 2021
  • 1 location
Neo-adjuvant Evaluation of Glioma Lysate Vaccines in WHO Grade II Glioma

This is a pilot neoadjuvant vaccine study in adults with WHO grade II glioma, for which surgical resection of the tumor is clinically indicated. Co-primary objectives are to determine: 1) the

corticosteroids
karnofsky performance status
poly iclc
initial diagnosis
oligodendroglioma
  • 111 views
  • 12 Jun, 2021
  • 1 location
A Study of the Treatment of Recurrent Malignant Glioma With rQNestin34.5v.2

This research study is evaluating an investigational drug, an oncolytic virus called rQNestin34.5v.2. This research study is a Phase I clinical trial, which tests the safety of an investigational drug and also tries to define the appropriate dose of the investigational drug as a possible treatment for this diagnosis of …

brain tumor
anaplastic oligodendroglioma
experimental drug
cyclophosphamide
oligodendroglioma
  • 58 views
  • 28 Jan, 2021
  • 2 locations
Genetically Modified T-cells in Treating Patients With Recurrent or Refractory Malignant Glioma

This phase I trial studies the side effects and best dose of genetically modified T-cell immunotherapy in treating patients with malignant glioma that has come back (recurrent) or has not

nitrosoureas
x-rays
karnofsky performance status
immunohistochemistry
platelet count
  • 60 views
  • 19 Feb, 2021
  • 2 locations
ONC201 in Pediatric H3 K27M Gliomas

/refractory H3 K27M gliomas. Arm A will define the RP2D for single agent ONC201 in pediatric patients with glioma who are positive for the H3 K27M mutation (positive testing in CLIA laboratory) and have

re-irradiation
nitrosoureas
corticosteroids
cancer
platelet count
  • 85 views
  • 16 May, 2021
  • 8 locations
Hyperpolarized Imaging in Diagnosing Participants With Glioma

This pilot trial studies the side effects of hyperpolarized carbon C 13 pyruvate magnetic resonance imaging (MRI) in diagnosing participants with glioma. Diagnostic procedures, such as

temozolomide
cancer
karnofsky performance status
MRI
renal function
  • 3 views
  • 25 Jan, 2021
  • 1 location
D2C7-IT With Atezolizumab for Recurrent Gliomas

with recurrent World Health Organization (WHO) grade IV malignant glioma at the Preston Robert Tisch Brain Tumor Center (PRTBTC) at Duke.

recurrent tumor
brain tumor
atezolizumab
neutrophil count
platelet count
  • 0 views
  • 16 May, 2021
  • 1 location