Gliomas Clinical Trials

A listing of Gliomas medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 114 clinical trials
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Phase I Study of Subventricular Zone Tumor Stem Cell Stereotactic Radiosurgery with Standard of Care Chemoradiation Therapy in newly Diagnosed Malignant Gliomas (WHO III and WHO IV Astrocytomas)

stereotactic radiosurgery will be more effective in destroying cancer stem cells than conventional radiation therapy, and (3) treatment will improve malignant glioma survival  

  • 4 views
  • 11 Jun, 2020
  • 1 location
Investigating Safety Tolerability Efficacy and PK of Olaparib in Paediatric Patients With Solid Tumours

A study to find out whether olaparib is safe and well tolerated when administered to children and adolescents with solid tumours.

  • 16 views
  • 02 Jun, 2021
  • 20 locations
Phase 1 Trial of D2C7-IT in Combination With 2141-V11 for Recurrent Malignant Glioma

This is a phase 1 study of an anti-CD40 monoclonal antibody (2141-V11) in combination with D2C7-IT for patients with recurrent World Health Organization (WHO) grade III or IV malignant glioma at

brain tumor
malignant glioma
recurrent malignant glioma
  • 0 views
  • 23 May, 2021
  • 1 location
Study of Acetazolamide With Temozolomide in Adults With Newly Diagnosed or Recurrent Malignant Glioma

This is a Phase I study that examines the rate of dose limiting side effects in patients with malignant astrocytoma treated with combination acetazolamide (ACZ) and temazolomide (TMZ). Eligible patients must have histologically proven newly diagnosed, O6-methylguanine-DNA methyltransferase (MGMT) methylated WHO grade III or IV astrocytoma and be planning to …

  • 1 views
  • 16 Jun, 2021
  • 1 location
TAK-580 In Gliomas and Other Tumors

This research study is studying a drug TAK-580 (MLN2480) as a possible treatment a low-grade glioma that has not responded to other treatments. The name of the study drug involved in this

ejection fraction
tak-580
measurable disease
  • 3 views
  • 05 Apr, 2021
  • 13 locations
[18F]Fluciclovine in Post-treatment Glioblastoma ( Axumin )

Subjects with histologically proven glioblastoma (GBM) who are suspected to have progression and are candidates for a surgical resection according to standard of care may be eligible for this study. Subjects may participate in this study if they are at least 18 years of age. Positron emission tomography (PET/CT) imaging …

chemoradiotherapy
karnofsky performance status
  • 1 views
  • 25 Jan, 2021
  • 1 location
A Study of HMPL-306 in Advanced Solid Tumors With IDH Mutations

An open label single-arm clinical trial to evaluate the safety, tolerability, PK, PD, and preliminary efficacy of HMPL-306 in advanced or metastatic solid tumors with IDH mutation.

  • 0 views
  • 03 Jun, 2021
  • 2 locations
Immunotherapy (Nivolumab and Ipilimumab) Before and After Surgery for the Treatment of Recurrent or Progressive High Grade Glioma in Children and Young Adults

This phase I trial studies the side effects of nivolumab and ipilimumab before and after surgery in treating children and young adults with high grade glioma that has come back (recurrent) or is

tumor progression
tumor cells
gilbert's syndrome
antineoplastic
platelet count
  • 0 views
  • 13 Jun, 2021
  • 7 locations
Study of LY3410738 Administered to Patients With Advanced Solid Tumors With IDH1 Mutations

, including but not limited to cholangiocarcinoma, chondrosarcoma, and glioma.

metastasis
cancer chemotherapy
measurable disease
gemcitabine
drainage
  • 0 views
  • 18 Jun, 2021
  • 48 locations
Phase 1b Study PVSRIPO for Recurrent Malignant Glioma in Children

grade III or IV malignant glioma, but evidence for efficacy will also be sought. The primary objective is to confirm the safety of the selected dose of PVSRIPO when delivered intracerebrally by

medulloblastoma
gliosarcoma
recurrent malignant glioma
rhabdoid tumor
platelet count
  • 64 views
  • 04 Apr, 2021
  • 1 location