Gliomas Clinical Trials

A listing of Gliomas medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 77 clinical trials
MRE Scan for the Assessment of Differences in Tissue Stiffness Between Radiation Necrosis and Recurrent Glioma in Patients With Previously Treated Gliomas

tumor tissue that has come back (recurrent) after treatment in patients with gliomas. Diagnostic procedures, such as MRE, may estimate the differences in tissue stiffness between radiation necrosis and

flair
recurrent glioma
intracranial glioma
MRI
  • 0 views
  • 22 Sep, 2021
  • 1 location
A Phase II Study of Pulse Reduced Dose Rate Radiation Therapy With Bevacizumab

progression in patients with recurrent high grade gliomas (grade III and grade IV). Patients will be placed in 1 of 4 groups based on their histologic diagnosis and prior exposure to bevacizumab.

temozolomide
bevacizumab
  • 18 views
  • 23 Sep, 2021
  • 1 location
Cereset for Caregivers

mirroring) intervention for a stressed population confronting an acute burden on their lives - caregivers of newly diagnosed high-grade glioma patients. The Cereset intervention is a closed-loop acoustic

who grade iii glioma
glioblastoma multiforme
  • 0 views
  • 24 Sep, 2021
  • 1 location
Study of the Effect NT-I7 on CD4 Counts in Patients With High Grade Gliomas

The purpose of this study is to determine the maximum tolerated dose (MTD) and select optimal biological doses (OBD) of the study drug NT-I7 in High Grade Glioma patients with severe lymphopenia

karnofsky performance status
corticosteroids
gliadel wafer
gliadel
dexamethasone
  • 0 views
  • 17 Sep, 2021
  • 12 locations
INCMGA00012 and Epacadostat in Combination With Radiation and Bevacizumab in Patients With Recurrent Gliomas

In this study, the investigators propose to combine INCMGA00012 with radiation therapy (RT) and bevacizumab with or without epacadostat in the treatment of recurrent glioblastoma (GBM). The investigators hypothesize that this combination provides a powerful synergy between RT and immune modulators to produce more robust anti-tumor immune response, induce tumor …

karnofsky performance status
gliosarcoma
aptt
neutrophil count
immunotherapeutic agent
  • 0 views
  • 22 Sep, 2021
  • 4 locations
Determining Dose of Regadenoson Most Likely to Transiently Alter the Integrity of the Blood-Brain Barrier in Patients With High Grade Gliomas

enroll patients with histologically confirmed high-grade gliomas to evaluate the ability of regadenoson to transiently disrupt a relatively intact blood-brain barrier (BBB). determine the best

hydroxychloroquine
astrocytoma, anaplastic
astrocytoma
regadenoson
nitrosoureas
  • 3 views
  • 18 Sep, 2021
  • 9 locations
BGB-290 and Temozolomide in Treating Isocitrate Dehydrogenase (IDH)1/2-Mutant Grade I-IV Gliomas

This phase I trial studies the side effects and best dose of BGB-290 and temozolomide in treating adolescents and young adults with IDH1/2-mutant grade I-IV glioma that is newly diagnosed or has

alkylating agents
corticosteroids
formalin-fixed paraffin-embedded
seizure
monoclonal antibodies
  • 24 views
  • 18 Sep, 2021
  • 20 locations
Phase I Study of Mebendazole Therapy for Recurrent/Progressive Pediatric Brain Tumors

This is a safety (Phase 1) trial using mebendazole for recurrent pediatric brain cancers that include medulloblastoma and high grade glioma, that are no longing responding to standard therapies

neutrophil count
treatment regimen
mebendazole
malignant brain tumor
brain tumor
  • 204 views
  • 22 Sep, 2021
  • 2 locations
Study of Binimetinib With Encorafenib in Adults With Recurrent BRAF V600-Mutated HGG

The goal of this study is to estimate the efficacy of encorafenib and binimetinib as measured by radiographic response in recurrent high-grade primary brain tumors.

hydroxychloroquine
tumor resection
carcinoma of the skin
BRAF
nitrosoureas
  • 24 views
  • 19 Sep, 2021
  • 9 locations
Testing the Use of the Immunotherapy Drugs Ipilimumab and Nivolumab Plus Radiation Therapy Compared to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Unmethylated Glioblastoma

This phase II/III trial compares the usual treatment with radiation therapy and temozolomide to radiation therapy in combination with immunotherapy with ipilimumab and nivolumab in treating patients with newly diagnosed MGMT unmethylated glioblastoma. Radiation therapy uses high energy photons to kill tumor and shrink tumors. Chemotherapy drugs, such as temozolomide, …

karnofsky performance status
gliosarcoma
tumor resection
MRI
nivolumab
  • 1 views
  • 23 Sep, 2021
  • 150 locations