Gliomas Clinical Trials

A listing of Gliomas medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 547 clinical trials
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Phase I Study of Subventricular Zone Tumor Stem Cell Stereotactic Radiosurgery with Standard of Care Chemoradiation Therapy in newly Diagnosed Malignant Gliomas (WHO III and WHO IV Astrocytomas)

stereotactic radiosurgery will be more effective in destroying cancer stem cells than conventional radiation therapy, and (3) treatment will improve malignant glioma survival  

  • 4 views
  • 11 Jun, 2020
  • 1 location
featured
A Phase 3, Randomized, Open-Label Study To Evaluate the Efficacy and Safety of Eflornithine with Lomustine Compared to Lomustine Alone in Patients with Anaplastic Astrocytoma That Progress/Recur after Irradiation and Adjuvant Temozolomide Chemotherapy

The purpose of this study is to compare the efficacy and safety of eflornithine in combination with lomustine, compared to lomustine taken alone, in treating patients whose anaplastic astrocytoma has recurred/progressed after radiation and temozolomide chemotherapy.  

  • 5 views
  • 11 Jun, 2020
  • 1 location
featured
N0577 (CODEL) Phase III Intergroup Study of Radiotherapy with Concomitant and Adjuvant Temozolomide versus Radiotherapy with Adjuvant PCV Chemotherapy in Patients with 1p/19q co-deleted Anaplastic Glioma or Low Grade Glioma

People who are diagnosed with an oligodendroglioma and who haven't yet undergone treatment may be eligible.  This study is comparing two standard regimens, radiation followed by PCV (Procarbazine, CCNU, and Vincristine) or radiation with temozolomide during and after radiation, to see which is better.  

temozolomide
vincristine
brain tumor
brain tumors
oligodendroglioma
  • 10 views
  • 22 Dec, 2020
  • 1 location
featured
Intraoperative Radiotherapy in Newly Diagnosed Glioblastoma Multiforme (INTRAGO-II)

INTRAGO II resembles a multicentric, prospective, randomized, 2-arm, open-label clinical phase III trial which tests if the median progression-free survival (PFS) of patients with newly diagnosed glioblastoma multiforme (GBM) can be improved by the addition of intraoperative radiotherapy (IORT) to standard radiochemotherapy.  

MRI
cancer
bevacizumab
  • 40 views
  • 11 Jun, 2020
  • 1 location
featured
CG01-GBM Standard Chemotherapy versus Chemotherapy Chosen by Cancer Stem Cell Chemosensitivity Testing in the Management of Patients with Recurrent Glioblastoma Multiforme (GBM)

People who were previously diagnosed with glioblastoma (Grade IV) or Grade III glioma, and now have evidence that their tumor has come back or has started to grow again, and who would otherwise be

brain tumor
glioblastoma
  • 117 views
  • 22 Dec, 2020
  • 1 location
featured
RTOG-0834: Phase III Trial on Concurrent and Adjuvant Temozolomide Chemotherapy in Non-1p/19q Deleted Anaplastic Glioma. The CATNON Intergroup Trial

RTOG-0834: Phase III Trial on Concurrent and Adjuvant Temozolomide Chemotherapy in Non-1p/19q Deleted Anaplastic Glioma. The CATNON Intergroup Trial

  • 112 views
  • 08 Nov, 2020
  • 1 location
  • 167 views
  • 18 Jun, 2021
  • 126 locations
Vinblastine +/- Bevacizumab in Children With Unresectable or Progressive Low Grade Glioma (LGG)

Grade Glioma aged 6 months to less than18 years of age at the time of initiation of therapy. Participants will be randomized to Arm A or Arm B. Arm A includes 68 weeks of single agent Vinblastine

corticosteroids
glomerular filtration rate
progressive disease
vinblastine
BRAF
  • 0 views
  • 24 Jan, 2021
  • 24 locations