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Metastatic Cancer Clinical Trials

A listing of Metastatic Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (4) clinical trials

Genetic Testing for Men With Metastatic Prostate Cancer

PRIMARY OBJECTIVES: I. To assess the frequency of pathogenic germline homologous recombination (HR) variants in men with metastatic prostate cancer (mPC). II. To collect patient reported outcome measures associated with genetic testing in men with mPC. III. To assess the utility of family history to enrich screening of population of ...

Phase N/A

Phase I/II Study of Immunotherapy Combination BN-Brachyury Vaccine M7824 ALT-803 and Epacadostat (QuEST1).

Background PD-1/PD-L1 signaling appears to be a major inhibitor of activated T cell anti-tumor immune responses. The rapid, deep and durable responses seen in various malignancies with PD-1/PD-L1 targeted agents demonstrate that blockade of this axis is key to facilitating immune responses within the tumor microenvironment (TME). Prostate cancer is ...

Phase

Safety Tolerability Pharmacokinetics and Anti-tumour Activity of ASK120067 in Locally Advanced and Metastatic Non Small Cell Lung Cancer

ASK120067 Tablets is a Epidermal Growth Factor Receptor (EGFR) mutation selective Tyrosine Kinase Inhibitor which can efficient suppress the EGFR T790M drug-resistant mutation tumor cell in Xenograft mouse model. This study aims at local advanced or metastatic non-small cell lung cancer patients with T790M drug-resistant mutation.

Phase

Establishing Organoids From Metastatic Pancreatic Cancer Patients the OPT-I Study.

Rationale: Pancreatic adenocarcinoma is a malignancy with a poor prognosis. Resection is the only curative option and still 5-year survival rate is less than 10 percent. However, most patients present with advanced disease and are provided with palliative care. The nature of the tumour and the intense stromal reaction around ...

Phase