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Headaches Clinical Trials

A listing of Headaches medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (26) clinical trials

French Database of Occipital Nerves Stimulation in the Treatment of Refractory Chronic Headache Disorders

The purpose of this non interventional research is to set up a French database, initially for 3 years, of patients suffering from refractory chronic headache disorders (chronic migraine, cluster headache, chronic paroxysmal hemicranias, SUNCT syndrome, hemicrania continua, cervicogenic headache disorders), and treated by occipital nerves stimulation. Every team using this ...

Phase N/A

Investigation of Serotonin Receptor Binding in the Migraine Brain Using Positron Emission Tomography

Migraine affects 16% of the world population and is one of the most disabling of all disorders. It is a complex brain disorder characterized primarily by recurrent headache attacks. The signaling molecule serotonin (5-hydroxytryptamine, 5-HT) has for decades been thought to play a central role in migraine pathophysiology. The most ...

Phase N/A

Acute Mental Stress During Lumbar Puncture

The consequences of being in a state of Acute Mental Stress are reduced working memory, decreased psychomotor performance, and impaired performance. Although some levels of increased stress response might be beneficial, there seems to be an upper-limit when performance is reduced. According to the Cognitive Activation Theory of Stress (CATS), ...

Phase N/A

eNeura SpringTMS Post-Market Observational US Study of Migraine

A prospective, non-randomized, single arm, multi-center observational study designed to evaluate the use of the SpringTMS system in reducing the frequency of headache days. Note: This is a NON-SIGNIFICANT RISK (NSR) study of a NON-SIGNIFICANT RISK (NSR) Device. It is a post market study of a NSR device cleared by ...

Phase N/A

Multi Cervical Unit Measures of Cervical Isometric Strength and Range of Motion: A Pilot Study

This study is designed to collect normative data on cervical isometric strength and range of motion to supplement an existing normative data base.

Phase N/A

The Role of CGRPand Nociceptin in Migraine

The release of the neuropeptide calcitonin gene-related peptide (CGRP) is thought to play a causative role in migraine. Nociceptin immunoreactivity and ORL-1 mRNA have been detected in human trigeminal ganglia where it was co-localized with CGRP. It may play a role in migraine pathogenesis. We are collecting the blood samples ...

Phase N/A

The Will Erwin Headache Research Center - Cluster Headache Study

The Will Erwin Headache Research Center will assemble a national registry of Cluster Headache patients and will sub-categorize and organize this cohort based on individuating characteristics including but not limited to type and severity of condition, associated symptoms, and medical/psychological issues (e.g., depression, disability, sleep). Detailed evaluations and classification will ...

Phase N/A

Influence of Main Psychological and Social Factors on Primary Headaches

The aim of our study is to describe the psychological patterns in a population of patients suffering of episodic migraine or chronic migraine with and without medication overuse and the level of disability. Data about migraine characteristics will be obtained using a standardized questionnaire. Socio-demographic data will be obtained for ...

Phase N/A

Neuroinflammatory Response and Headache Control in Patients After Subarachnoid Hemorrhage

Persistent headache is a significant medical issue that affects 20% of patients who survive an aneurysmal subarachnoid hemorrhage (SAH). This headache may last years, severely affecting quality of life. Laboratory evidence suggests that the persistent headache may be a result of a maladaptive neuroinflammatory response to the hemorrhage injury that ...

Phase N/A

Assessing the Diagnostic Accuracy of an On-line Questionnaire for Diagnosis of Primary Headache Disorders

The worldwide current gold standard for diagnosing headaches is the International Classification of Headache Disorders (ICHD 3 beta). Adhering strictly to ICHD criteria has been problematic for accurately diagnosing patients in the clinic and as for clinical trials. To address these issues, an online instrument was developed that successfully diagnosis ...

Phase N/A