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Headaches Clinical Trials

A listing of Headaches medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (209) clinical trials

Introvision for Migraine and Headaches

Randomized, single-center, waiting-list control group study: Introvision as preventative in Migraine Randomized, single center, waiting-list group control study to evaluate the effect of Introvison, a mental and emotional self regulation method to reduce headache days in patients with migraine, migraine and tension type headache and chronic migraine. The number of ...

Phase N/A

Metoclopramide for Post Traumatic Headache

Nearly 1.5 million patients present to US emergency departments annually following head trauma. Headache is a frequent symptom of victims of head trauma. The purpose of this study is to see if an intravenous medication called metoclopramide can improve the symptoms of patients with acute post-traumatic headache.


Primary Headache and Psychological Factors Mental Functioning and Attachment Modalities.

The review of the literature shows the keen interest and the need for this type of research to better understand the main psychological factors involved in primary headaches. The current vagueness, the lack of knowledge regarding the aspects associated psychological and the lack of studies on the French population can ...

Phase N/A

Long-term Prognosis of Cluster Headache: a Retrospective Cohort Study

Cluster headache is a syndrome characterized by disabling headache and accompanying autonomic symptoms. Despite cluster headache is called "suicide headache", its natural history has not been well investigated. The investigators aimed to investigate its disease course, overall prognosis, and treatment pattern in retrospective cohort.

Phase N/A

Prospective Multi-Center Evaluation of the Efficacy of Peripheral Trigger Decompression Surgery for Migraine Headaches

According to the peripheral trigger theory of migraine headaches, nociceptive inputs from irritated or compressed cranial nerve branches can lead to neurovascular changes in the brain that cause migraine headaches. Advanced treatments aimed at deactivating the peripheral trigger points can be administered to patients who have failed medical management of ...

Phase N/A

Treatment of Chronic Migraine Headaches.

A combination of dexamethasone, lidocaine and thiamine (pat.), may bring changes in the pattern of sympathetic and parasympathetic nerve signaling at the level vasa nervorum. These changes may down-regulate the hyperexcitable sympathetic signals at the level of adventitia and consequently the medial layer of vasa nervorum and providing long term ...


CGRP-induced Migraine Attacks in Patients Who Have Tried Anti-CGRP Monoclonal Antibody Treatment

Calcitonin gene-related peptide (CGRP) plays a role in migraine pathophysiology. Infusions of CGRP can trigger migraine-like attacks in migraine patients and antibodies against CGRP or the CGRP receptor significantly reduces the number of migraine days per month when administered regularly. Some patients however, do not experience migraine attack after CGRP ...

Phase N/A

Ultrasound Greater Occipital Nerve Block at C2 Level Compared to Landmark-based Greater Occipital Nerve Block

Hypothesis: A novel ultrasound-guided greater occipital nerve (GON) block at the level of C2 will result in significantly lower pain scores after 4 weeks when compared with a traditional landmark-guided approach at the superior nuchal line. The greater occipital nerve (GON) has been implicated in several conditions that prompt referral ...

Phase N/A

The Effect of Topiramate on Etonogestrel Concentrations in Contraceptive Implant Users

A prospective, non-inferiority study to evaluate the pharmacokinetic effect of topiramate on serum Etonogestrel (ENG) levels in contraceptive implant users.


Efficacy and Safety of Tx360 Transnasal Sphenopalatine Ganglion Block in the Treatment of Chronic Migraine

This is a phase III, multi-center, randomized, double-blind, placebo-controlled, prospective, clinical trial examining the outcomes of subjects with chronic migraine headache who are treated with 0.3cc of 0.5% bupivacaine bilaterally vs 0.3cc of sterile water bilaterally, each delivered to the mucosal surface of the SPG through each nare with the ...